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  1. Ten novel spectrophotometric approaches were developed for the initial examination of the Hydroxychloroquine and Paracetamol medications. These procedures are straightforward, specific, easy to use, and provid...

    Authors: Samar S. Elbaramawi, Sobhy M. El-Adl, Alaa Nafea, Amr A. Mattar and Mahmoud M. Sebaiy
    Citation: BMC Chemistry 2024 18:104
  2. Carbazole-based molecules containing thiosemicarbazide functional groups are recognized for their diverse biological activities, particularly in enhancing therapeutic anticancer effects through inhibiting cruc...

    Authors: İrfan Çapan, Mohammed Hawash, Mohammed T. Qaoud, Levent Gülüm, Ezgi Nurdan Yenilmez Tunoglu, Kezban Uçar Çifci, Bekir Sıtkı Çevrimli, Yusuf Sert, Süleyman Servi, İrfan Koca and Yusuf Tutar
    Citation: BMC Chemistry 2024 18:102
  3. Indium phosphide (InP) is a binary semiconductor composed of indium and phosphorus. It has a zinc blende crystal structure, which is a type of cubic lattice structure. This lattice is composed of indium and ph...

    Authors: Muhammad Salman, Asad Ullah, Shahid Zaman, Emad E. Mahmoud and Melaku Berhe Belay
    Citation: BMC Chemistry 2024 18:101
  4. Brucellosis poses a significant challenge in the medical field as a systemic infection with a propensity for relapse. This study presented a novel approach to brucellosis treatment, enhancing the efficacy of d...

    Authors: Saeideh Gohari, Seyed Mostafa Hosseini, Fatemeh Nouri, Rasoul Yousefimashouf, Mohammad Reza Arabestani and Mohammad Taheri
    Citation: BMC Chemistry 2024 18:100
  5. The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has led to over six million deaths worldwide. In human immune system, the type 1 interferon (IFN) pathway plays a crucial role in fighting viral infection...

    Authors: Muhammad Suleman, Abduh Murshed, Kashif Imran, Abbas Khan, Zafar Ali, Norah A. Albekairi, Dong-Qing Wei, Hadi M. Yassine and Sergio Crovella
    Citation: BMC Chemistry 2024 18:99
  6. The pursuit of advanced multifunctional compounds has gained significant momentum in recent scientific endeavours. This study is dedicated to elucidating the synthesis, rigorous characterization, and multiface...

    Authors: F. M. Mashood Ahamed, M. Syed Ali Padusha, A. Mushira Banu, Swastika Maitra, Hanan M. Alharbi, Vinoth Kumarasamy, Daniel E. Uti, Popat Mohite, Athanasios Alexiou and Iftikhar Ali
    Citation: BMC Chemistry 2024 18:98
  7. Alfuzosin hydrochloride and tadalafil fixed-dose combination tablets were recently formulated for the treatment of individuals with lower urinary tract symptoms caused by benign prostatic hyperplasia. Herein, ...

    Authors: Ali Alqahtani, Taha Alqahtani and Sherif Ramzy
    Citation: BMC Chemistry 2024 18:96
  8. To improve the thermal and combustion properties of nanothermites, a design theory of changing the state of matter and structural state of the reactants during reaction was proposed. The Al/MoO3/KClO4 (Kp) nanoth...

    Authors: Jialin Chen, Shutao Li, Mengnan Dai, Ming An, Rui Song, Yeqing Chen, Jiaxing Song, Quanwei Tian, Xiting Zhong and Qiushi Yan
    Citation: BMC Chemistry 2024 18:91
  9. An electroanalytical methodology was developed by direct differential pulse voltammetric (DPV) measurement of Levodopa (LD), Carbidopa (CD) and Entacapone (ENT) mixture using bare glassy carbon electrode (GCE)...

    Authors: Finan T. Hindam, Basma M. Eltanany, Amal M. Abou Al Alamein, Rasha M. El Nashar and Reham M. Arafa
    Citation: BMC Chemistry 2024 18:90
  10. This study aimed to measure both the solubility and thermodynamics of salicylic acid in binary solvent mixtures of (2-propanol + ethylene glycol) and (2-propanol + propylene glycol) at different temperatures i...

    Authors: Fatemeh Dabagh, Fatemeh Khalili, Aynaz Zarghampour, Salar Hemmati, Jalal Hanaee, Elaheh Rahimpour and Abolghasem Jouyban
    Citation: BMC Chemistry 2024 18:84
  11. Pentachlorophenol is a pesticide widely known for its harmful effects on sewage, causing harm to the environment. In previous studies, our group identified adsorption as a crucial factor in catalytic ozonation...

    Authors: Cristian Valdés, Cristina Quispe, Rubén A. Fritz, Rodrigo Andler, Jorge Villaseñor, Gina Pecchi, Edgardo Avendaño, Alvaro Delgadillo, William N. Setzer and Javad Sharifi-Rad
    Citation: BMC Chemistry 2024 18:83
  12. Modification of marketed drugs is an important way to develop drugs because its safety and clinical applicability. Oxygen-nitrogen heterocycles are a class of important active substances discovered in the proc...

    Authors: Xixi Hou, Longfei Mao, Yajie Guo, Lan Wang, Lizeng Peng, Huili Wang, Jianxue Yang, Sanqiang Li and Yue-Ming Li
    Citation: BMC Chemistry 2024 18:97
  13. Cholesteryl ester transfer protein (CETP) is a promising therapeutic target for cardiovascular diseases. It effectively lowers the low-density lipoprotein cholesterol levels and increases the high-density lipo...

    Authors: Yanfeng Liu, Liangying Deng, Feng Ding, Qiang Wang, Shuran Zhang, Nana Mi, Wenhui Zhang, Bailin Zeng, Huangjin Tong and Lixing Wu
    Citation: BMC Chemistry 2024 18:95
  14. In the investigation of active ingredients from natural products, current technologies relying on drug–target affinity recognition analysis face significant challenges. This is primarily due to their limited s...

    Authors: Xiaomin Huang, Ting Wang, Ludan Wang, Yantao Sun, Ziru Zhang and Yajun Zhang
    Citation: BMC Chemistry 2024 18:94
  15. Two rapid, precise, and sensitive stability-indicating high performance chromatographic methods for the measurement of Teriflunomide in its degradation products’ existence were developed. These were RP-HPLC an...

    Authors: Shereen A. Boltia, Mai M. Mora, Nahla S. Ismail and Hala E. Zaazaa
    Citation: BMC Chemistry 2024 18:93
  16. The simultaneous assay of duloxetine hydrochloride (DLX) and avanafil (AVN) in their pure forms, synthetic mixtures, and spiked human plasma was achieved using a novel, eco-friendly, sensitive, and specific HP...

    Authors: Sayed M. Derayea, Hadeer A. Elhamdy, Mohamed Oraby and Khalid M. Badr El-Din
    Citation: BMC Chemistry 2024 18:92
  17. In this study, we firstly established and verified a method by ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) for the analysis of vilazodone and its metabolite M10 in rat plasma,...

    Authors: Mengming Xia, Xinhao Xu, Chaojie Chen, Hualu Wu, Ren-ai Xu and Changlv Wang
    Citation: BMC Chemistry 2024 18:89
  18. Two sensitive, straightforward and repeatable chromatographic techniques were developed for the determination of Cytarabine HCl and Dexamethazone in their pure form and spiked human plasma without prior separa...

    Authors: Maimana A. Magdy, Ahmed M. Elgebaly, Ahmed A. Taha, Nourddin W. Ali and Nehal F. Farid
    Citation: BMC Chemistry 2024 18:88
  19. 2,6-Di-tert-butyl-4-methylphenol (BHT) is an excellent antioxidant that is easily oxidized to 2,6-di-tert-butyl-4-hydroperoxyl-4-methyl-2,5-cyclohexadienone (BHTOOH). For the safety of BHT production and usage...

    Authors: Suyi Dai, Min Liang, Haijun Cheng, Chang Yu, Weiguang Li, Fang Lai, Li Ma and Xiongmin Liu
    Citation: BMC Chemistry 2024 18:87
  20. In this study, efficiency of functionalized carbon nanotube as a potential delivery system for imatinib anti-cancer drug was investigated. Accordingly, carboxyl and hydroxyl functionalized carbon nanotube were...

    Authors: Masume Rezazade, Sepideh Ketabi and Mahnaz Qomi
    Citation: BMC Chemistry 2024 18:85
  21. Simple, quick, cost-effective, and environmentally friendly analytical methods for quality assurance and control roles for different medicines, including Tetrcyclines, are most significantly needed. Also, diff...

    Authors: Misganaw Gashaw, Thomas Layloff, Ariaya Hymete and Ayenew Ashenef
    Citation: BMC Chemistry 2024 18:82
  22. 6-mercaptopurine (6-MP) is a chemotherapy drug mainly used to treat leukemia. It is a persistent organic pollutant and can remain in the environment for a long period of time. The presence of 6-MP in the envir...

    Authors: Leila Raisi, Sayyed Hossein Hashemi, Ahmad Jamali Keikha and Massoud Kaykhaii
    Citation: BMC Chemistry 2024 18:81
  23. In the current work, a rapid, simple, low-cost, and sensitive smartphone-based colorimetric sensor array coupled with pattern-recognition methods was proposed for the determination and differentiation of some ...

    Authors: Mina Adampourezare, Behzad Nikzad, Sanaz Sajedi-Amin and Elaheh Rahimpour
    Citation: BMC Chemistry 2024 18:80
  24. We report the synthesis of sulfonated copolyaniline/polysafranin/L-ascorbic acid/Ag@SiO2 fine powdered nanocomposites and investigate the influence of incorporating the dye on their conductivity. The composite wa...

    Authors: Hammed H. A. M. Hassan, Marwa Abdel Fattah and Fatma Abdel Maged
    Citation: BMC Chemistry 2024 18:79
  25. In this study, novel nanomagnetic catalysts, namely Fe2O3-MgO@choline formate (Ch. F.) and Fe2O3-MgO@choline cyanide (Ch. CN), were synthesized through immobilizing choline-based ion liquids to magnetic support v...

    Authors: Ehsan Kamali, Fahim Dreekvandy, Abolfazl Mohammadkhani and Akbar Heydari
    Citation: BMC Chemistry 2024 18:78
  26. Multidrug-resistant tuberculosis (particularly resistant to pyrazinoic acid) is a life-threatening chronic pulmonary disease. Running a marketed regime specifically targets the ribosomal protein subunit-1 (Rps...

    Authors: Bader S. Alotaibi
    Citation: BMC Chemistry 2024 18:77
  27. Nod-like receptor protein 3 (NLRP-3), is an intracellular sensor that is involved in inflammasome activation, and the aberrant expression of NLRP3 is responsible for diabetes mellitus, its complications, and m...

    Authors: Chandni Hayat, Vetriselvan Subramaniyan, Mubarak A. Alamri, Ling Shing Wong, Asaad Khalid, Ashraf N. Abdalla, Sahib Gul Afridi, Vinoth Kumarasamy and Abdul Wadood
    Citation: BMC Chemistry 2024 18:76
  28. Two new Cobalt(II) complexes 12 and 13 have been synthesized from 2-[(E)-(3-acetyl-4-hydroxyphenyl)diazenyl]-4-(2-hydroxyphenyl)thiophene-3-carboxylic acid (11) as a novel ligand. These three new compounds were c...

    Authors: Emmanuel Sopbué Fondjo, Sorelle Songmi Feuze, Jean-de-Dieu Tamokou, Apollinaire Tsopmo, Giscard Doungmo, Peter Simon Friedrich Wilhelm, Donald Léonel Feugap Tsamo, Bruno Lenta Ndjakou and Jules Roger Kuiate
    Citation: BMC Chemistry 2024 18:75
  29. This study presents a stability indicating high-performance liquid chromatography HPLC method for the determination of cenobamate (CNB) in presence of its main impurity (CNB H-impurity) and degradation product...

    Authors: Samah F. EL-Malla, Fotouh R. Mansour, Almoataz Bellah B. Elbastawissy and Samar H. Elagamy
    Citation: BMC Chemistry 2024 18:74
  30. Cyclin-dependent kinase 8 (CDK8) has emerged as a promising target for inhibiting cancer cell function, intensifying efforts towards the development of CDK8 inhibitors as potential cancer therapeutics. Mutatio...

    Authors: Raziye Aghahasani, Fereshteh Shiri, Hossein Kamaladiny, Fatemeh Haddadi and Somayeh Pirhadi
    Citation: BMC Chemistry 2024 18:73
  31. Toluene, a prominent member of volatile organic compounds (VOCs), exerts a substantial adverse influence on both human life and the environment. In the context of advanced oxidation processes, the ·OH radical ...

    Authors: Yumin Mao, Lijuan Yang, Siqi Liu, Yunchang Song, Mengchao Luo and Yongxue Guo
    Citation: BMC Chemistry 2024 18:72
  32. Bio-based coating materials have received increased attention because of their low-cost, environmentally friendly, and sustainable properties. In this paper, a novel coating material was developed to coat urea...

    Authors: Yanle Guo, Fengyuan Zhuang, Qunxiang Cui, Shugang Zhang, Zhenping Hao, Yiyun Shi, Hao Lu and Xiaoqing Shi
    Citation: BMC Chemistry 2024 18:71
  33. In this article, we present the design and synthesis of amino-7,8-dihydro-4H-chromenone derivatives as possible inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) for the management of ...

    Authors: Ali Asadipour, Yaghoub Pourshojaei, Moein Mansouri, Elham Mahdavizadeh, Cambyz Irajie, Javad Mottaghipisheh, Ehsan Faghih-Mirzaei, Mohammad Mahdavi and Aida Iraji
    Citation: BMC Chemistry 2024 18:70
  34. The starting compound 3-amino-1,7-dihydro-4H-pyrazolo[4,3-c]pyridine-4,6(5H)-dione (1) is reacted with each of diketone and β-ketoester, forming pyridopyrazolo[1,5-a]pyrimidines 4a,b and 14a,b, respectively. The ...

    Authors: Nadia Hanafy Metwally, Emad Abdullah Deeb and Ibrahim Walid Hasani
    Citation: BMC Chemistry 2024 18:68
  35. A novel series of 4-nitrophenylpiperazine derivatives (4am) was designed and synthesized as potential tyrosinase inhibitors. Comprehensive characterization using 1H-NMR, 13C-NMR, CNH, and IR techniques was perfo...

    Authors: Mehdi Asadi, Fahime Fayazi, Aida Iraji, Reyhaneh Sabourian, Homa Azizian, Mannan Hajimahmoodi, Bagher Larijani, Mohammad Mahdavi and Massoud Amanlou
    Citation: BMC Chemistry 2024 18:67
  36. Therapeutic drug monitoring is an important clinical testing of the drugs to monitor their concentrations in plasma in order to guarantee their optimal impact, and to avoid any side effects resulting from drug...

    Authors: Nada Hesham, Maha A. Hegazy and Hebatallah A. Wagdy
    Citation: BMC Chemistry 2024 18:66
  37. As pharmaceutical analysis progresses towards environmental sustainability, there is a growing need to enhance the safety and health conditions for analysts. Consequently, the incorporation of chemometrics int...

    Authors: Eman A. Madbouly, Abdalla A. El-Shanawani, Sobhy M. El-adl and Ahmed S. Abdelkhalek
    Citation: BMC Chemistry 2024 18:65
  38. In pursuit of developing novel cholinesterase (ChE) inhibitors through molecular hybridization theory, a novel series of isoindolin-1,3-dione-based acetohydrazides (compounds 8ah) was designed, synthesized, and ...

    Authors: Ahmad Nazarian, Fahime Abedinifar, Haleh Hamedifar, Mohammad Hashem Hashempur, Mohammad Mahdavi, Nima Sepehri and Aida Iraji
    Citation: BMC Chemistry 2024 18:64
  39. In this research, a novel magnetic zirconium-based metal-organic framework (Fe3O4@SiO2@MIP-202, MMOF), was fabricated, fully characterized, and applied for the batch-mode solid phase extraction of trace amounts o...

    Authors: Amin Piri, Massoud Kaykhaii, Mostafa Khajeh and Ali Reza Oveisi
    Citation: BMC Chemistry 2024 18:63
  40. A rapid and efficient analytical method was established to quantify indoxyl sulfate (IS) in plasma through extraction technique with a deep eutectic solvent (DES) and spectrofluorimetric method. DES (choline c...

    Authors: Samira Shafiee, Siavoush Dastmalchi, Afshin Gharekhani and Ali Shayanfar
    Citation: BMC Chemistry 2024 18:61
  41. Phytochemical investigation of Key lime (Citrus aurantifolia L., F. Rutaceae) peels afforded six metabolites, known as methyl isolimonate acetate (1), limonin (2), luteolin (3), 3ˋ-hydroxygenkwanin (4), myricetin...

    Authors: Abeer H. Elmaidomy, Usama Ramadan Abdelmohsen, Ahmed M. Sayed, Faisal H. Altemani, Naseh A. Algehainy, Denisa Soost, Thomas Paululat, Gerhard Bringmann and Esraa M. Mohamed
    Citation: BMC Chemistry 2024 18:60
  42. Lung cancer is a disease with a high mortality rate and it is the number one cause of cancer death globally. Approximately 12–14% of non-small cell lung cancers are caused by mutations in KRASG12C. The KRASG12C i...

    Authors: Amar Ajmal, Hind A Alkhatabi, Roaa M. Alreemi, Mubarak A. Alamri, Asaad Khalid, Ashraf N. Abdalla, Bader S. Alotaibi and Abdul Wadood
    Citation: BMC Chemistry 2024 18:57
  43. Gold and silver nanoparticles have witnessed increased scientific interest due to their colourful colloidal solutions and exceptional applications. Comparing the localized surface plasmon resonance (LSPR) of g...

    Authors: Khadiga M. Kelani, Maha M. Ibrahim, Nesreen K. Ramadan, Eman S. Elzanfaly and Sherif M. Eid
    Citation: BMC Chemistry 2024 18:56
  44. Montelukast sodium (MLK) and Levocetirizine dihydrochloride (LCZ) are widely prescribed medications with promising therapeutic potential against COVID-19. However, existing analytical methods for their quantif...

    Authors: Noha S. Katamesh, Ahmed Emad F. Abbas and Shimaa A. Mahmoud
    Citation: BMC Chemistry 2024 18:54

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