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  1. Water solubility is perhaps the single most important physical–chemical property determining the environmental fate and effects of organic compounds. Its determination is particularly challenging for compounds...

    Authors: Daniel J. Letinski, Aaron D. Redman, Heidi Birch and Philipp Mayer

    Citation: BMC Chemistry 2021 15:52

    Content type: Methodology article

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  2. Local sequence context is known to have an impact on the mutational pattern seen in cancer. The RAS genes and a smoking carcinogen, Benzo[a]pyrene diol epoxide (BPDE), have been utilised to explore these context ...

    Authors: Georgina E. Menzies, Ian A. Prior, Andrea Brancale, Simon H. Reed and Paul D. Lewis

    Citation: BMC Chemistry 2021 15:51

    Content type: Research article

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  5. Iron phosphate, Fe2 (HPO4)3*4H2O, is synthesized at ambient temperature, using the inorganic sol–gel method coupled to the microwave route. The experimental conditions for the gelling of Fe (III)-H3PO4 system are...

    Authors: Fz. Maarouf, S. Saoiabi, K. Azzaoui, C. Chrika, H. Khalil, S. Elkaouni, S. Lhimr, O. Boubker, B. Hammouti and S. Jodeh

    Citation: BMC Chemistry 2021 15:48

    Content type: Research article

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  6. Thiamine (vitamin B1) is an essential micronutrient in the human diet, found both naturally and as a fortification ingredient in many foods and supplements. However, it is susceptible to degradation due to heat, ...

    Authors: Adrienne L. Voelker, Lynne S. Taylor and Lisa J. Mauer

    Citation: BMC Chemistry 2021 15:47

    Content type: Research article

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  7. Edible insects constitute a potential source of alternative proteins as a food supplement. The present study aimed to investigate the chemical composition, energy and nutritional values, the digestibility and ...

    Authors: Aminata Séré, Adjima Bougma, Bazoin Sylvain Raoul Bazié, Esther Traoré, Charles Parkouda, Olivier Gnankiné and Imael Henri Nestor Bassolé

    Citation: BMC Chemistry 2021 15:46

    Content type: Research article

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  8. Presently available chemical based synthetic preservative have emerged with various side effects, so the aspiration of natural and side effect free novel preservative has been greatly increased. As the natural...

    Authors: Amit Lather, Sunil Sharma and Anurag Khatkar

    Citation: BMC Chemistry 2021 15:45

    Content type: Research article

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  9. Zanthoxylum nitidium (Roxb.) DC (Rutaceae) is well known for inhibiting the proliferation of human gastric, liver, kidney and lung cancer cells, though research on its potential use in treating leukaemia is relat...

    Authors: Ying Deng, Tongtong Ding, Lulu Deng, Xiaojiang Hao and Shuzhen Mu

    Citation: BMC Chemistry 2021 15:44

    Content type: Research article

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  10. The present study evaluated the compost quality from municipal solid waste (MSW) and organic additives of coffee by-products and leaf of Millettia ferruginea. Compost sample (n = 30) was taken from fresh compost ...

    Authors: Masresha Mamo, Henok Kassa, Lalit Ingale and Stefaan Dondeyne

    Citation: BMC Chemistry 2021 15:43

    Content type: Research article

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  11. Silver orthophosphate (Ag3PO4) has received enormous attention over the past few years for its higher visible light photocatalytic performance as well as for various organic pollutants degradation in aqueous medi...

    Authors: Karim Dânoun, Rida Tabit, Abdelaziz Laghzizil and Mohamed Zahouily

    Citation: BMC Chemistry 2021 15:42

    Content type: Research article

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  12. Discovering and screening for potential anti-obesity, anti-diabetic, anticancer, and antioxidant treatments from natural products still in recent times the main goal for many pharmaceutical scientists. The pre...

    Authors: Nidal Jaradat, Hanaa Dacca, Mohammed Hawash and Murad N. Abualhasan

    Citation: BMC Chemistry 2021 15:41

    Content type: Research Article

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  13. Currently, available therapies for diabetes could not achieve normal sugar values in a high percentage of treated patients. In this research project, a series of 17 benzodioxole derivatives were evaluated as a...

    Authors: Mohammed Hawash, Nidal Jaradat, Suhaib Shekfeh, Murad Abualhasan, Ahmad M. Eid and Linda Issa

    Citation: BMC Chemistry 2021 15:40

    Content type: Research article

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  14. Loop diuretics are commonly used in clinical practice to manage high fluid loads and to control fluid balance. In this paper, a novel quantitative analysis method for multiple components with a single marker (...

    Authors: Fuchao Chen, Baoxia Fang, Peng Li and Sicen Wang

    Citation: BMC Chemistry 2021 15:39

    Content type: Research article

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  15. Pyrazoles have attracted particular attention due to the diverse biological activities associated with this heterocyclic system, and some have been shown to be cytotoxic to several human cell lines. Several dr...

    Authors: José Eduardo Cadena-Cruz, Luis M. Guamán-Ortiz, Juan Carlos Romero-Benavides, Natalia Bailon-Moscoso, Kevin E. Murillo-Sotomayor, Nadia V. Ortiz-Guamán and Jorge Heredia-Moya

    Citation: BMC Chemistry 2021 15:38

    Content type: Research article

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  16. This mini-review assesses supercritical carbon dioxide (scCO2) extraction and high-pressure carbon dioxide pre-treatment technologies for valorisation of corn stover agricultural residues with particular focus on...

    Authors: Pakin Noppawan, Adrienne Gallant Lanctôt, Maria Magro, Pablo Gil Navarro, Nontipa Supanchaiyamat, Thomas M. Attard and Andrew J. Hunt

    Citation: BMC Chemistry 2021 15:37

    Content type: Review

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  17. Phospholipid (PL)–hyaluronic acid (HA) interactions are relevant to aging-associated vitreous humor liquefaction, therapies for dry eye disease, skin-care products and synovial joint lubrication. Phosphatidyl ...

    Authors: Anthony Ewurum, Abhishek Ashok Alur, Margaret Glenn, Abigail Schnepf and Douglas Borchman

    Citation: BMC Chemistry 2021 15:36

    Content type: Research article

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  18. The alkylation of benzene with methanol is an important synthetic method that is widely used in various chemical production processes. However, obtaining a high selectivity for xylene and annihilating the MTO ...

    Authors: Dongliang Wang, Yanwei Li, Yu Zhao, Dong Ji, Peng Dong and Guixian Li

    Citation: BMC Chemistry 2021 15:35

    Content type: Research article

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  19. The nano-sized particles enhance the exposed surface area of the active part of the catalyst, thereby increasing the contact between precursors and catalyst considerably. In this study, nano-SiO2/1,5-diazabicyclo...

    Authors: Maryam Mehravar, Bi Bi Fatemeh Mirjalili, Elaheh Babaei and Abdolhamid Bamoniri

    Citation: BMC Chemistry 2021 15:34

    Content type: Research article

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  20. Artemisia splendens from the Asteraceae family is a new source of biologically active compounds. The current study investigated to evaluate antimicrobial and cytotoxicity activity of methanolic extracts and th...

    Authors: Fariba Heshmati Afshar, Masumeh Zadehkamand, Zahra Rezaei, Abbas Delazar, Vahideh Tarhriz and Parina Asgharian

    Citation: BMC Chemistry 2021 15:33

    Content type: Research article

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  21. Cucumis prophetarum is traditionally used to treat liver and lung disorders, heart failure, diarrhea, gonorrhea, skin infections, intestinal problems and cancer. In the present work, the isolation of two novel co...

    Authors: Wario Galma, Milkyas Endale, Emebet Getaneh, Rajalakshmanan Eswaramoorthy, Temesgen Assefa and Yadessa Melaku

    Citation: BMC Chemistry 2021 15:32

    Content type: Research article

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  22. In this study, different drying methodologies (convective air, oven and microwave) of Myrtus communis L. (M. communis L.) leaves were conducted to investigate their effects on the levels of phenolic compounds, an...

    Authors: Ahmed Snoussi, Ismahen Essaidi, Hayet Ben Haj Koubaier, Houda Zrelli, Ibrahim Alsafari, Tesic Živoslav, Jelena Mihailovic, Muhummadh Khan, Abdelfatteh El Omri, Tanja Ćirković Veličković and Nabiha Bouzouita

    Citation: BMC Chemistry 2021 15:31

    Content type: Research article

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  23. 1,2,4-oxadiazole derivatives exhibited significant anti-cancer activity when they were evaluated, against human cancer cell lines. They also showed anti-inflammatory, analgesic, diabetic, immunosuppressive, α,β3-...

    Authors: Ravi Kumar Bommera, Shashikala Kethireddy, Rajeshwar Reddy Govindapur and Laxminarayana Eppakayala

    Citation: BMC Chemistry 2021 15:30

    Content type: Research Article

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  25. In diabetes, increased accumulation of sorbitol has been associated with diabetic complications through polyol pathway. Aldose reductase (AR) is one of the key factors involved in reduction of glucose to sorbi...

    Authors: Mohsinul Mulk Bacha, Humaira Nadeem, Sumera Zaib, Sadia Sarwar, Aqeel Imran, Shafiq Ur Rahman, Hafiz Saqib Ali, Muazzam Arif and Jamshed Iqbal

    Citation: BMC Chemistry 2021 15:28

    Content type: Research article

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  26. Environment-friendly fast and accurate mid-infrared spectroscopic methods have been developed for the quantitative analysis of doxorubicin hydrochloride (DOX) and arterolane maleate (ALM) in bulk and marketed ...

    Authors: Ranju Bansal, Ranjit Singh and Khushpal Kaur

    Citation: BMC Chemistry 2021 15:27

    Content type: Research Article

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  27. The floral scents of plants play a key role in plant reproduction through the communication between plants and pollinators. Aquilegia as a model species for studying evolution, however, there have been few studie...

    Authors: Hua-Ying Wang, Wei Zhang, Jian-Hua Dong, Hao Wu, Yuan-Hong Wang and Hong-Xing Xiao

    Citation: BMC Chemistry 2021 15:26

    Content type: Research article

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  28. The design of new polymers able to filter the electromagnetic spectrum and absorb distinctly in the UV and high-energy part of visible spectrum is crucial for the development of semi-transparent solar cells. H...

    Authors: Peshawa O. Amin, Kamal Aziz Ketuly, Salah Raza Saeed, Fahmi F. Muhammadsharif, Mark D. Symes, Avishek Paul and Khaulah Sulaiman

    Citation: BMC Chemistry 2021 15:25

    Content type: Research article

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  29. Phycocyanin is a blue natural food colorant with multiple health benefits. Here we propose an efficient phycocyanin extraction method from Arthrospira platensis from Mexico. Three extraction methods were applied ...

    Authors: Sanghamitra Khandual, Edgar Omar Lopez Sanchez, Hugo Espinosa Andrews and Jose Daniel Padilla de la Rosa

    Citation: BMC Chemistry 2021 15:24

    Content type: Research article

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  30. Propionic acid as a very valuable chemical is in high demand, and it is industrially produced via the oxo-synthesis of ethylene or ethyl alcohol and via the oxidation of propionaldehyde with oxygen. It is urge...

    Authors: Minxue Liu, Fengli Yu, Bing Yuan, Congxia Xie and Shitao Yu

    Citation: BMC Chemistry 2021 15:23

    Content type: Research Article

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  31. Rilpivirine (RPV) was approved by the U.S. FDA (Food and Drug Administration) in 2011 to treat individuals infected with human immunodeficiency virus 1 (HIV-1). Significantly, rilpivirine is three fold more po...

    Authors: Tao Zhang, Jiapei Yang, Zhongxia Zhou, Zhipeng Fu, Srinivasulu Cherukupalli, Dongwei Kang, Peng Zhan and Xinyong Liu

    Citation: BMC Chemistry 2021 15:22

    Content type: Research article

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  32. Mulberry leaves are used in traditional Chinese medicine and contain numerous active substances that are known to be beneficial for human health. The aim of this study was to investigate the phenolic compositi...

    Authors: Zhenjiang Wang, Cuiming Tang, Gengsheng Xiao, Fanwei Dai, Sen Lin, Zhiyi Li and Guoqing Luo

    Citation: BMC Chemistry 2021 15:21

    Content type: Research article

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  33. With the increasing demand for antimicrobial agents and the spread of antibiotic resistance in pathogens, the exploitation of plant oils to partly replace antibiotic emerges as an important source of fine chem...

    Authors: Ahmed M. Senan, Binru Yin, Yaoyao Zhang, Mustapha M. Nasiru, Yong‐Mei Lyu, Muhammad Umair, Javaid A. Bhat, Sicheng Zhang and Li Liu

    Citation: BMC Chemistry 2021 15:20

    Content type: Research article

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  34. Fungal polysaccharides belong to a very important class of biological macromolecules in nature, and have complex monosaccharide composition and structure. These studies on structure and biological activity of ...

    Authors: Lei Guo, Hongwei Dai, Jiayu Ma, Junmin Wang, Yan Hua and Lingyun Zhou

    Citation: BMC Chemistry 2021 15:19

    Content type: Research Article

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  37. To evaluate the impact of cold fermentation time on bagel rolls, the key aroma-active compounds in the volatile fractions obtained from three different bagel rolls through solvent assisted flavor evaporation (...

    Authors: Ola Lasekan, Fatma Dabaj, Megala Muniandy, Nurul Hanisah Juhari and Adeseye Lasekan

    Citation: BMC Chemistry 2021 15:16

    Content type: Research article

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  38. Chemical and pharmacological investigations were performed on the stems of Cordia batesii (Boraginaeae); chemical studies included quantum calculations applied on a newly described compound.

    Authors: Eric Robert Tiam, Dominique Serge Ngono Bikobo, Ibrahim Mbouombouo Ndassa, Norbert Mbabi Nyemeck II, Auguste Abouem A Zintchem, Lawrence Ayong, Patrick Hervé Betote Diboué, Bruno Lenta Ndjakou, Joséphine Ngo Mbing and Dieudonné Emmanuel Pegnyemb

    Citation: BMC Chemistry 2021 15:15

    Content type: Research article

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  39. The polyphenol distribution in fresh waxy corns of different color varieties and their functional activities, which may be useful for treating various chronic diseases, were investigated. The in vitro antioxid...

    Authors: Lirong Chen, Yuqiu Guo, Xiaoyue Li, Kuijie Gong and Kaichang Liu

    Citation: BMC Chemistry 2021 15:14

    Content type: Research article

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  40. Nuclear magnetic resonance (NMR)-based relaxometry is widely used in various fields of research because of its advantages such as simple sample preparation, easy handling, and relatively low cost compared with...

    Authors: Yasuhiro Date, Feifei Wei, Yuuri Tsuboi, Kengo Ito, Kenji Sakata and Jun Kikuchi

    Citation: BMC Chemistry 2021 15:13

    Content type: Research article

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  42. The distribution of drugs could not be controlled in the conventional delivery systems. This has led to the developing of a specific nanoparticle-based delivery system, called smart drug delivery systems. In c...

    Authors: Ehsan Alimohammadi, Reza Maleki, Hossein Akbarialiabad and Mohammad Dahri

    Citation: BMC Chemistry 2021 15:11

    Content type: Research article

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  43. Amoxicillin (AMX), which is one of the β-lactam antibiotics used in the treatment of bacterial infections, is known to have a serious mechanism of resistance necessitating continuous monitoring of its level in...

    Authors: Adane Kassa and Meareg Amare

    Citation: BMC Chemistry 2021 15:10

    Content type: Research Article

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  44. This work presents an investigation on the composition and structure of polysaccharides from the roots of Tetrastigma hemsleyanum (THP) and its associated antioxidant activity. It further explores the protective ...

    Authors: Qi Huang, Wen He, Ilkhomjon Khudoyberdiev and Chun-Lin Ye

    Citation: BMC Chemistry 2021 15:9

    Content type: Research article

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  45. The global pandemic of coronavirus disease (COVID-19) caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) created a rush to discover drug candidates. Despite the efforts, so far no vaccine o...

    Authors: Marcos V. S. Santana and Floriano P. Silva-Jr

    Citation: BMC Chemistry 2021 15:8

    Content type: Research article

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  46. Many natural compounds have been identified and synthesized by the advancement of bryophytes phytochemistry studies. This work aimed to report the composition of Neckeropsis undulata (Hedw.) Reichardt moss volati...

    Authors: Thyago G. Miranda, Raynon Joel M. Alves, Ronilson F. de Souza, José Guilherme S. Maia, Pablo Luis B. Figueiredo and Ana Cláudia C. Tavares-Martins

    Citation: BMC Chemistry 2021 15:7

    Content type: Research article

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  47. Nano-eggshell/Ti(IV) as a novel naturally based catalyst was prepared, characterized and applied for the synthesis of dihydropyrano[2,3-c]pyrazole derivatives. The characterization of nano-eggshell/Ti(IV) was per...

    Authors: Arefeh Dehghani Tafti, Bi Bi Fatemeh Mirjalili, Abdolhamid Bamoniri and Naeimeh Salehi

    Citation: BMC Chemistry 2021 15:6

    Content type: Research article

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  48. Triazole is an important heterocyclic moiety that occupies a unique position in heterocyclic chemistry, due to its large number of biological activities. It exists in two isomeric forms i.e. 1,2,4-triazole and...

    Authors: Mukesh Kumari, Sumit Tahlan, Balasubramanian Narasimhan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Vasudevan Mani and Saloni Kakkar

    Citation: BMC Chemistry 2021 15:5

    Content type: Research article

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  49. Salvia macrosiphon Boiss. is an aromatic perennial herb belonging to the family Lamiaceae. Phytochemical studies and biological activities of this plant have been rarely documented in the literature. The current...

    Authors: Majid Balaei-Kahnamoei, Mahdieh Eftekhari, Mohammad Reza Shams Ardekani, Tahmineh Akbarzadeh, Mina Saeedi, Hossein Jamalifar, Maliheh Safavi, Sohrab Sam, Naghmeh Zhalehjoo and Mahnaz Khanavi

    Citation: BMC Chemistry 2021 15:4

    Content type: Research article

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  50. Salting-out induced liquid–liquid microextraction method has been developed for plasma sample treatment before determination of alogliptin by high performance liquid chromatography with UV detection. Several p...

    Authors: Sherin F. Hammad, Inas A. Abdallah, Alaa Bedair and Fotouh R. Mansour

    Citation: BMC Chemistry 2021 15:2

    Content type: Research article

    Published on:

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