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  1. Content type: Research article

    In order to overcome the challenges of microbial resistance as well as to improve the effectiveness and selectivity of chemotherapeutic agents against cancer, a novel series of 4-(4-bromophenyl)-thiazol-2-amin...

    Authors: Deepika Sharma, Sanjiv Kumar, Balasubramanian Narasimhan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah and Vasudevan Mani

    Citation: BMC Chemistry 2019 13:60

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  2. Content type: Research article

    This paper describes the application of response surface methodology (RSM) to develop a miniaturized metal organic framework based pipette-tip solid phase extraction for the extraction of malachite green (MG),...

    Authors: Sayyed Hossein Hashemi, Massoud Kaykhaii, Ahmad Jamali Keikha, Elahe Mirmoradzehi and Ghasem Sargazi

    Citation: BMC Chemistry 2019 13:59

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  3. Content type: Research article

    Escalating energy security, burgeoning population and rising costs of fossil fuels have focussed our attention on tapping renewable energy sources. As the utilization of food crops for biofuel production culmi...

    Authors: Rintu Banerjee, Anjani Devi Chintagunta and Subhabrata Ray

    Citation: BMC Chemistry 2019 13:58

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  4. Content type: Research article

    Thanks to its specific chemical and physical properties, graphene has aroused growing interest in many fields of Science and Technology. The present study focuses on the properties of microcrystalline chitosan...

    Authors: Marta E. Lichawska, Aleksander Kufelnicki and Magdalena Woźniczka

    Citation: BMC Chemistry 2019 13:57

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  5. Content type: Research article

    Identification and screening of cultivars rich in bioactive phytoconstituents can be potentially useful to make nutrient-dense dishes and in medicinal formulations. In this study, we have identified, character...

    Authors: Awraris Derbie Assefa, Susanna Choi, Jae-Eun Lee, Jung-Sook Sung, On-Sook Hur, Na-Young Ro, Ho-Sun Lee, Suk-Woo Jang and Ju-Hee Rhee

    Citation: BMC Chemistry 2019 13:56

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  6. Content type: Research article

    Many reports have also shown that the silver nanoparticles can effectively increase the anticancer drug activity and intensely enhance the drug curative effect. The adsorption of 6MP on nanomaterials has recei...

    Authors: Hongjiang Ren, Fan Chen, Xiaojun Li and Yaping He

    Citation: BMC Chemistry 2019 13:55

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  7. Content type: Research article

    Diabetes is an emerging metabolic disorder. α-Glucosidase inhibitors, such as acarbose, delay the hydrolysis of carbohydrates by interfering with the digestive enzymes. This action decreases the glucose absorp...

    Authors: Hatem A. Abuelizz, Nor Azman N. I. Iwana, Rohaya Ahmad, El-Hassane Anouar, Mohamed Marzouk and Rashad Al-Salahi

    Citation: BMC Chemistry 2019 13:52

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  8. Content type: Research article

    The general approach to the synthesis of metal complexes begins with ligand synthesis, followed by ligand reaction with metal salts to afford organometallic complexes. Our research group first reported a one-p...

    Authors: Mei Luo, Jing Cheng Zhang, Hao Yin, Cheng Ming Wang, Susan Morris-Natschke and Kuo-Hsiung Lee

    Citation: BMC Chemistry 2019 13:51

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  9. Content type: Research article

    Nitrogen containing heterocycles are widely used and investigated by pharmaceutical industry, as they are important in discovery and designing of new drug molecules. Drugs with a benzimidazole nucleus possess ...

    Authors: Sumit Tahlan, Sanjiv Kumar, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Vasudevan Mani, Ranjana Pathania and Balasubramanian Narasimhan

    Citation: BMC Chemistry 2019 13:50

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  10. Content type: Research article

    In search of new antimicrobial and cytotoxic agents, a series of new naphthol diazenyl scaffold based Schiff bases (NS1NS23) was efficiently synthesized by condensation of 2-hydroxy naphthaldehyde azo dyes with ...

    Authors: Harmeet Kaur, Jasbir Singh and Balasubramanian Narasimhan

    Citation: BMC Chemistry 2019 13:49

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  11. Content type: Research article

    Pyrazolines show different biological activities. In recent years, interest in the chemistry of hydrazonoyl halides has been renewed. 1,3,4-Thiadiazoles are one of the most common heterocyclic pharmacophores w...

    Authors: Abdou O. Abdelhamid, Ibrahim E. El Sayed, Yasser H. Zaki, Ahmed M. Hussein, Mangoud M. Mangoud and Mona A. Hosny

    Citation: BMC Chemistry 2019 13:48

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  12. Content type: Research article

    The medicinal plant Tirpitzia sinensis has been used by the Zhuang ethnic people in mountainous areas of Southwest China to stop bleeding, invigorate blood circulation, and treat inflammation and wounds. In order...

    Authors: Ronghui Gu, Yuehu Wang, Shibiao Wu, Yeling Wang, Ping Li, Li Xu, Yue Zhou, Ze’e Chen, Edward J. Kennelly and Chunlin Long

    Citation: BMC Chemistry 2019 13:47

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  13. Content type: Research article

    To combat the antimicrobial and anticancer drug resistance by pathogens and cancerous cells, efforts has been made to study the pharmacological activities of newly synthesized N-(4-(4-bromophenyl)thiazol-2-yl)-2-...

    Authors: Deepika Sharma, Sanjiv Kumar, Balasubramanian Narasimhan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah and Vasudevan Mani

    Citation: BMC Chemistry 2019 13:46

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  14. Content type: Research article

    Urease are responsible for several pathogenic states in human as well as in animals and its inhibition is utmost urgent. Clinically used drugs are associated with many side effects; recently several researches...

    Authors: Ritu Kataria and Anurag Khatkar

    Citation: BMC Chemistry 2019 13:45

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  15. Content type: Research article

    The existence of heavy metals and coliform bacteria contaminants in aquatic system of Akaki river basin, a sub city of Addis Ababa, Ethiopia has become a public concern as human population increases and land d...

    Authors: Feleke Terefe Fanta, Amare Aregahegn Dubale, Dawit Firemichael Bebizuh and Minaleshewa Atlabachew

    Citation: BMC Chemistry 2019 13:44

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  16. Content type: Research article

    The increased multidrug resistance among antimalarial drugs produces the urgency of potent anti malarial to combat resistant malaria and the malaria burden worldwide. The protein which may prevent the growth o...

    Authors: Jagbir Singh, Rani Mansuri, Sonam Vijay, Ganesh Chandra Sahoo, Arun Sharma and Mahesh Kumar

    Citation: BMC Chemistry 2019 13:43

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  17. Content type: Research article

    The present study reveals the robust and facile methodology for the synthesis of massively selective dispiro-3-phenylpyrrolothiazole hybrids via one-pot 1,3-dipolar cycloaddition reaction by environmentally su...

    Authors: Govindasami Periyasami, Karuppiah Ponmurugan, Natarajan Arumugam, Raju Sureshkumar, Mostafizur Rahaman, Durairaju Periyan, Naif Abdullah Al-Dhabi, Shaykha Alzahly and Ali Aldalbahi

    Citation: BMC Chemistry 2019 13:42

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  18. Content type: Research article

    Plants have always played important role in treating human and animal diseases as a therapeutic agent for traditional medicine. Through extensive research throughout the world, potential of natural products ha...

    Authors: Ritu Kataria and Anurag Khatkar

    Citation: BMC Chemistry 2019 13:41

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  19. Content type: Research article

    A facile and convenient method for the synthesis of acridines and its derivatives was developed through one-pot, three-component condensation reaction of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione, ...

    Authors: M. Mujahid Alam, Ahmed T. Mubarak, Mohammed A. Assiri, S. Merajuddin Ahmed and Ahmed M. Fouda

    Citation: BMC Chemistry 2019 13:40

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  20. Content type: Research article

    A convenient approach for (1E,3E)-1,4-diarylbuta-1,3-dienes via intermolecular Heck reaction of olefins and β-bromostyrenes promoted by μ-OMs palladium–dimer complex has been successfully developed. The products ...

    Authors: Xueliang Zhou, Yuan Zhou, Qiang Zhu, Huimin Chen, Nan Wu, Xiangru Wen and Zhou Xu

    Citation: BMC Chemistry 2019 13:39

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  21. Content type: Research article

    Natural based inhibitors of monoamine oxidase are promising drug candidates for the treatment of several neurodegenerative and neuropsychological disorders including depression, anxiety, Parkinson’s disease an...

    Authors: Priyanka Dhiman, Neelam Malik and Anurag Khatkar

    Citation: BMC Chemistry 2019 13:38

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  22. Content type: Research article

    Thiazole is a core structural motif presents in a wide range of natural products. Thiazole derivatives also have a wide range of medicinal and biological properties.

    Authors: Mona A. Hosny, Yasser H. Zaki, Wafaa A. Mokbel and Abdou O. Abdelhamid

    Citation: BMC Chemistry 2019 13:37

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  23. Content type: Research article

    Herein, 2-(2-methoxyphenoxy)-1-phenylethanol (β-O-4), 2-methoxyphenyl anisole (α-O-4) and 4-phenoxyphenol (4-O-5) were selected as typical lignin model compounds. Given the effectiveness of traditional acid–base ...

    Authors: J. Guo, Yu L. Ma, Jia Y. Yu, Yu J. Gao, Ning X. Ma and Xiao Y. Wu

    Citation: BMC Chemistry 2019 13:36

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  24. Content type: Research article

    4-Thiazolidinone ring is reported to have almost all types of biological activities. Also, it present in many marketed drugs.

    Authors: Yahia N. Mabkhot, Mohammed M. Alharbi, Salim. S. Al-Showiman, Saied M. Soliman, Nabila A. Kheder, Wolfgang Frey, Abdulrhman Asayari, Abdullatif Bin Muhsinah and H. Algarni

    Citation: BMC Chemistry 2019 13:35

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  25. Content type: Research article

    penta-1,4-diene-3-one oxime ether and quinazolin-4(3H)-one derivatives possess favorable agricultural activities. Aiming to discover novel molecules with highly-efficient agricultural activities, a series of pent...

    Authors: Lijuan Chen, Xiaobin Wang, Xu Tang, Rongjiao Xia, Tao Guo, Cheng Zhang, Xiangyang Li and Wei Xue

    Citation: BMC Chemistry 2019 13:34

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  26. Content type: Research article

    Functionalized copolymers were synthesized and are proposed as hosts of RNA. The copolymers are based on carboxymethyl cellulose and poly-(ethylene glycol)-OH. These copolymers were functionalized with two ami...

    Authors: Magali Hernández, Gerardo Leyva, Jonathan J. Magaña, Ariel Guzmán-Vargas, Carlos Felipe, Víctor Lara and Enrique Lima

    Citation: BMC Chemistry 2019 13:33

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  27. Content type: Research article

    Plants either in raw form or their isolated bioactive constituents are utilized as complementary and alternative medicine in various disorders. The present study was designed to evaluate chief phytochemical co...

    Authors: Riffat Batool, Muhammad Rashid Khan, Moniba Sajid, Saima Ali and Zartash Zahra

    Citation: BMC Chemistry 2019 13:32

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  28. Content type: Research article

    AlN films were deposited on Si substrates using a reactive RF magnetron sputtering process and then the films were annealed by using different laser powers and wavelengths (355 nm, 532 nm and 1064 nm). For all...

    Authors: H. K. Lin, Y. J. Huang, W. C. Shih, Y. C. Chen and W. T. Chang

    Citation: BMC Chemistry 2019 13:30

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  29. Content type: Research article

    Priming is a valuable, facile and well-established technique used to enhance seed quality to achieve rapid germination, establishment of stress resistance and improvement of crop yields. Different natural and ...

    Authors: Arruje Hameed, Amjad Hameed, Tahir Farooq, Razia Noreen, Sadia Javed, Shaheera Batool, Ashfaq Ahmad, Tahsin Gulzar and Matloob Ahmad

    Citation: BMC Chemistry 2019 13:29

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  30. Content type: Research article

    The occurrence of emerging pollutants like pharmaceuticals and related compounds in the aquatic and terrestrial environments is of increasing concern. Ciprofloxacin is one of the pharmaceuticals which is activ...

    Authors: Teshome Gezahegn, Bisratewongel Tegegne, Feleke Zewge and Bhagwan Singh Chandravanshi

    Citation: BMC Chemistry 2019 13:28

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  31. Content type: Research article

    Lychee pericarp is rich in phenolic and has good antioxidant activity. The effects of simulated gastric (SGF) and intestinal fluid (SIF) digestion on the contents, composition, and antioxidant activities of th...

    Authors: Qingzhu Zeng, Zhuohui Xu, Mingrui Dai, Xuejiao Cao, Xiong Xiong, Shan He, Yang Yuan, Mingwei Zhang, Lihong Dong, Ruifen Zhang and Dongxiao Su

    Citation: BMC Chemistry 2019 13:27

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  32. Content type: Research article

    The molecular structure of the 2-(4-oxo-3-phenylthiazolidin-2-ylidene) malononitrile (3) is calculated using DFT B3LYP/6-311G(d, p) method. The calculated geometric parameters are in good agreement with the exper...

    Authors: Yahia N. Mabkhot, Salim S. Al-Showiman, A. Barakat, S. M. Soliman, Nabila A. Kheder, Mohammed M. Alharbi, Abdulrahman Asayari, Abdullatif Bin Muhsinah, Asad Ullah and Syed Lal Badshah

    Citation: BMC Chemistry 2019 13:25

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  33. Content type: Research article

    Mangroves plants and their endophytes represent a natural source of novel and bioactive compounds. In our ongoing research on mangrove endophytes from the Panamanian Pacific Coast, we have identified several b...

    Authors: Dioxelis Lopéz, Lilia Cherigo, Luis C. Mejia, Marco A. Loza-Mejía and Sergio Martínez-Luis

    Citation: BMC Chemistry 2019 13:22

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  34. Content type: Research article

    Proanthocyanidin (PAC) is a promising compound that has displayed its potent antineoplastic properties with a specific intrinsic pathway. This precise us to explore the phyto-preventive effect of PAC against c...

    Authors: Mani Suganya, Balasubramanian Mythili Gnanamangai, Balasubramani Ravindran, Soon Woong Chang, Arokiyaraj Selvaraj, Chandramohan Govindasamy, Mohamed Farouk Elsadek and Ponnusamy Ponmurugan

    Citation: BMC Chemistry 2019 13:21

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  35. Content type: Methodology article

    Measuring concentrations of metabolites of estradiol and progesterone in urine, instead of measuring serum concentrations, is common in research and also is used in patient care. The primary aim of this study ...

    Authors: Mark Newman, Suzanne M. Pratt, Desmond A. Curran and Frank Z. Stanczyk

    Citation: BMC Chemistry 2019 13:20

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  36. Content type: Research article

    For the first time, the design and preparation of magnetic polyvinyl alcohol (Fe3O4@PVA) nanocomposite film as a novel nanocatalyst was accomplished by in situ precipitation method. To enhance the catalysis activ...

    Authors: Ali Maleki, Maryam Niksefat, Jamal Rahimi and Zoleikha Hajizadeh

    Citation: BMC Chemistry 2019 13:19

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  37. Content type: Research article

    Titanium dioxide (TiO2) is added in sunscreens due to its ability to absorb ultraviolet (UV) light. However, upon irradiation of UV light, reactive oxygen species particularly hydroxyl radical which can damage hu...

    Authors: Mohamad Nasir Mohamad Ibrahim, Anwar Iqbal, Chai Chuan Shen, Showkat Ahmad Bhawani and Farook Adam

    Citation: BMC Chemistry 2019 13:17

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  38. Content type: Research article

    Indole based thiadiazole derivatives (122) have synthesized, characterized by NMR and HREI-MS and evaluated for β-Glucuronidase inhibition. All compounds showed outstanding β-glucuronidase activity with IC50 val...

    Authors: Noor Barak Almandil, Muhammad Taha, Mohammed Gollapalli, Fazal Rahim, Mohamed Ibrahim, Ashik Mosaddik and El Hassane Anouar

    Citation: BMC Chemistry 2019 13:14

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  39. Content type: Research article

    Dihydrofolate reductase (DHFR) is an important target for antimetabolite class of antimicrobials because it participates in purine synthesis. 2-mercaptobenzimidazole (2MBI) has similar structural features as p...

    Authors: Sumit Tahlan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Vasudevan Mani and Balasubramanian Narasimhan

    Citation: BMC Chemistry 2019 13:12

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  40. Content type: Research article

    This work deals with the synthesis and characterization of the novel 5-((5-chloro-1H-indol-2-yl)methylene)-1,3-diethyl-2-thioxodihydro-pyrimidine-4,6(1H,5H)-dione π-bridge (D–A–D) donor–acceptor–donor compound. I...

    Authors: Mezna Saleh Altowyan, Assem Barakat, Abdullah Mohammed Al-Majid, Hazem A. Ghabbour, Abdelkader Zarrouk and Ismail Warad

    Citation: BMC Chemistry 2019 13:11

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