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  1. In this work, 11 novel compounds based on vaniline and benzylidenehydrazine structure were synthesized with various substituents on phenyl aromatic ring of the molecule and evaluated as tyrosinase inhibitors. ...

    Authors: Aida Iraji, Tina Adelpour, Najmeh Edraki, Mahsima Khoshneviszadeh, Ramin Miri and Mehdi Khoshneviszadeh

    Citation: BMC Chemistry 2020 14:28

    Content type: Research article

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  2. Congo red (CR) is an anionic azo dye widely used in many industries including pharmaceutical, textile, food and paint industries. The disposal of huge amount of CR into the various streams of water has posed a...

    Authors: Syed Rizwan Shafqat, Showkat Ahmad Bhawani, Salma Bakhtiar and Mohamad Nasir Mohamad Ibrahim

    Citation: BMC Chemistry 2020 14:27

    Content type: Research article

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  3. MiR-21, a non-coding miRNA with 22 nucleotides, plays an important part in the proliferation, invasion, and metastasis of tumor cells. The present study demonstrates that isomers of chiral ruthenium(II) comple...

    Authors: Yin Feng, Jing Shu, Liangzhong Yao, Yutao Lan, Lianbao Ye, Wenjie Mei and Ying Ding

    Citation: BMC Chemistry 2020 14:26

    Content type: Research article

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  4. Looking at the extensive biological potential of thiazolidine-2,4-dione (TZD) moiety, a new series of thiazolidine-2,4-dione analogues was synthesized. Different spectral techniques (1H-NMR, IR, MS etc.) were use...

    Authors: Harsh Kumar, Aakash Deep and Rakesh Kumar Marwaha

    Citation: BMC Chemistry 2020 14:25

    Content type: Research article

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  5. Three series of 2-(4-methylsulfonylphenyl) indole derivatives have been designed and synthesized. The synthesized compounds were assessed for their antimicrobial, COX inhibitory and anti-inflammatory activitie...

    Authors: Ahmed M. M. Shaker, Eman K. A. Abdelall, Khaled R. A. Abdellatif and Hamdy M. Abdel-Rahman

    Citation: BMC Chemistry 2020 14:23

    Content type: Research article

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  6. Near-infrared (NIR) fluorescence imaging is a noninvasive technique that provides numerous advantages for the real-time in vivo monitoring of biological information in living subjects without the use of ionizi...

    Authors: Chunlong Sun, Wen Du, Baoqin Wang, Bin Dong and Baogui Wang

    Citation: BMC Chemistry 2020 14:21

    Content type: Review

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  7. The properties of potato flour will be different due to different processing parameters, which will affect their processing adaptability. In this paper, different potato flour were investigated to determine vi...

    Authors: Ke Zhang, Yang Tian, Chenglong Liu and Wentong Xue

    Citation: BMC Chemistry 2020 14:20

    Content type: Research article

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  8. In this paper, we describe synthesis and application of an iron porphyrinc metal–organic framework PCN-222(Fe) for solid phase extraction of aspartame, an artificial non-saccharine sweetener, from gum, juice a...

    Authors: Zahra Safaei Moghaddam, Massoud Kaykhaii, Mostafa Khajeh and Ali Reza Oveisi

    Citation: BMC Chemistry 2020 14:19

    Content type: Research article

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  9. Chemical investigation of the essential oil obtained from the heartwood of Erythroxylum monogynum Roxb. yielded three beyerene type diterpenoids ent-beyer-15-ene (1), ent-beyer-15-en-19-ol (erythroxylol A) (2) an...

    Authors: T. M. Samantha Gome Tennakoon, G. M. Kamal Bandara Gunaherath, K. Tuley Dayananda De Silva, Chayanika Padumadasa, D. Siril Abeywickrama Wijesundara and Ajita Mahendra Abeysekera

    Citation: BMC Chemistry 2020 14:18

    Content type: Research article

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  10. Following publication of the original article [1], the author reported an error in the reference citation. In Results and Discussion section, Zhang et al. [2] should be cited after the first and third sentence...

    Authors: Wei Zhang, Yafeng Zuo, Fengqing Xu, Tongsheng Wang, Jinsong Liu and Deling Wu

    Citation: BMC Chemistry 2020 14:16

    Content type: Correction

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    The original article was published in BMC Chemistry 2019 13:128

  11. In this study, a functionalized multiwalled carbon nanotube (MWCNT)-coated solid-phase microextraction (SPME) fiber was developed for concentrating analytes in aqueous samples. Sodium deoxycholate (NaDC) was u...

    Authors: Xueqing Zhou, Yanli Xie, Zhendong Zhao and Wenyan Fu

    Citation: BMC Chemistry 2020 14:15

    Content type: Research article

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  12. With the improvement and advance in cancer diagnosis and treatment, the cancer is still a major cause of morbidity and mortality throughout the world. Obviously, new breakthroughs in therapies remain be urgent...

    Authors: Zhen-Hui Xin, Ya-Li Meng, Wen-Jing Jiang, Ya-Peng Li, Li-Ping Ge, Cun-Hui Zhang, Lian-Na Liu and Yan-Fei Kang

    Citation: BMC Chemistry 2020 14:13

    Content type: Research article

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  13. Neurodegenerative disorders follow numerous pathological ways concerning overexpression of monoamine oxidase and formation of reactive oxygen species. The computational design of the piperine derivatives has g...

    Authors: Priyanka Dhiman, Neelam Malik and Anurag Khatkar

    Citation: BMC Chemistry 2020 14:12

    Content type: Research article

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  14. To formulate a nanoformulation (PLGA-NPs) and to improve brain bioavailability for thymoquinone (THQ) through intranasal (i.n.) drug delivery, using a newly UHPLC-PDA developed the method and validated. Five d...

    Authors: Niyaz Ahmad, Rizwan Ahmad, Sadiq Al Qatifi, Mahdi Alessa, Hassan Al Hajji and Md Sarafroz

    Citation: BMC Chemistry 2020 14:10

    Content type: Research article

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  15. Corydalis yanhusuo W.T. Wang alkaloids are mainly divided into three categories: protoberberine, prototropine and aporphine alkaloids. Therefore, we have taken into account these three alkaloid contents when extr...

    Authors: Yongping Zhang, Zuhua Wang, Jian Xu, Fangfang Yang, Chuanyang Dai, Weijie Xie, Zhu Liang and Songbo Su

    Citation: BMC Chemistry 2020 14:9

    Content type: Research article

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  16. Isolated bioactive components of plants or their raw extract are utilized as complementary or alternate remedy in copious illnesses. The current research was aimed at assessing the activity of aloin A isolated...

    Authors: Addai-Mensah Donkor, Martin Ntiamoah Donkor and Ngmenpone Kuubabongnaa

    Citation: BMC Chemistry 2020 14:8

    Content type: Research article

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  17. This study was conducted to evaluate the potential of pineapple peel (PP) and pineapple crown leaves (PCL) as the substrate for vanillic acid and vanillin production. About 202 ± 18 mg L−1 and 120 ± 11 mg L−1 of ...

    Authors: Pei Ling Tang and Osman Hassan

    Citation: BMC Chemistry 2020 14:7

    Content type: Research article

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  18. In the present study, we report the synthesis of various quinoxaline derivatives from direct condensation of substituted aromatic 1,2-diamine with 1,2-dicarbonyl catalyzed by nanostructured pyrophosphate Na2PdP2O

    Authors: Karim Dânoun, Younes Essamlali, Othmane Amadine, Hassan Mahi and Mohamed Zahouily

    Citation: BMC Chemistry 2020 14:6

    Content type: Research article

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  19. Extensive bioactivities of alkaloids from the genus Macleaya (Macleaya cordata (Willd.) R. Br. and Macleaya microcarpa (Maxim.) Fedde) have been widely reported, as well as more and more concerned from the scient...

    Authors: Chunmei Sai, Jian’an Wang, Binjie Li, Lin Ding, Huiyun Wang, Qibao Wang, Huiming Hua, Fangpeng Zhang and Qiang Ren

    Citation: BMC Chemistry 2020 14:5

    Content type: Research article

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  20. Zizania latifolia is easily lignified after harvesting, leading to the degradation of food quality and commercial value. Thus, this study evaluated the effect of radio frequency (RF) treatments on lignification i...

    Authors: Changwen Ye, Chen He, Bowen Zhang, Lixuan Wang and Lufeng Wang

    Citation: BMC Chemistry 2020 14:4

    Content type: Research article

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  21. A novel polystyrene sulfonate sodium (PSS) magnetic material was prepared by surface-initiated atom transfer radical polymerization (SI-ATRP). The starting materials were brominated magnetic material as the ca...

    Authors: Huachun Liu, Bolin Gong, Yanqiang Zhou, Zhian Sun, Xiaoxiao Wang and Shanwen Zhao

    Citation: BMC Chemistry 2020 14:3

    Content type: Research article

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  22. A new donor-π-acceptor derived from phenothiazine, namely 2-(2-((10-hexyl-10H-phenothiazin-3-yl)methylene)-3-oxo-2,3-dihydroinden-1-ylidene) malononitrile (PTZON) was synthesized and fully characterized, and i...

    Authors: Fatimah A. M. Al-Zahrani, Reda M. El-Shishtawy, Abdullah M. Asiri, Amerah M. Al-Soliemy, Khloud Abu Mellah, Nahed S. E. Ahmed and Abdesslem Jedidi

    Citation: BMC Chemistry 2020 14:2

    Content type: Research article

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  23. A hybrid magnetic material γFe2O3@Sh@cu2O was easily prepared from Shilajit (Sh) decorated Fe3O4 and copper acetate. The prepared magnetic hybrid material was fully characterized using different analysis, includi...

    Authors: Fereshteh Norouzi and Shahrzad Javanshir

    Citation: BMC Chemistry 2020 14:1

    Content type: Research article

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  24. Mainstream tobacco smoke is a complex and dynamic aerosol, consisting of particulate and vapour phases. Most approaches to determine mainstream smoke toxicant yields are based on offline techniques that limit ...

    Authors: Jenni Hawke, Graham Errington and Matthias Bente von Frowein

    Citation: BMC Chemistry 2019 13:135

    Content type: Research article

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  25. Safety, environmental and economic setbacks are driving industries to find greener approaches to extract bioactive compounds from natural resources. Pressurized hot water extraction (PHWE) is among the solvent...

    Authors: Noor Hidayah Mohd Jusoh, Atiqah Subki, Swee Keong Yeap, Ken Choy Yap and Indu Bala Jaganath

    Citation: BMC Chemistry 2019 13:134

    Content type: Research article

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  26. Eleven new tetrahydrobenzo[b]pyran derivatives were synthesized via a three component reaction of different aromatic aldehydes, methyl cyanoacetate and 1,3-cyclohexadione, with water as solvent under catalyst-...

    Authors: Mandlenkosi Robert Khumalo, Surya Narayana Maddila, Suresh Maddila and Sreekantha B. Jonnalagadda

    Citation: BMC Chemistry 2019 13:132

    Content type: Research article

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  27. The current work deals with fabrication and validation of a new highly Fe3+ selective sensor based on benzo-18-crown-6 (b-18C6) using the potentiometric method. The proposed sensor revealed satisfactory performan...

    Authors: Somayeh Badakhshan, Saeid Ahmadzadeh, Anoushiravan Mohseni-Bandpei, Majid Aghasi and Amir Basiri

    Citation: BMC Chemistry 2019 13:131

    Content type: Research article

    Published on:

  28. The side reactions of dehalogenation or C–N coupling tend to occur when halogenated aromatic amines are prepared by catalytic hydrogenation reduction of halogenated aromatic nitro compounds. In this paper, we ...

    Authors: Haichang Guo, Renhua Zheng, Huajiang Jiang, Zhenyuan Xu and Aibao Xia

    Citation: BMC Chemistry 2019 13:130

    Content type: Research article

    Published on:

  29. In this work, using DNA and exonuclease-I (Exo-I) as signal amplification strategy, a novel and facile electrochemical aptasensor was constructed for fumonisin B1 (FB1) detection. The G-rich complementary DNA (cD...

    Authors: Min Wei, Fei Zhao, Shuo Feng and Huali Jin

    Citation: BMC Chemistry 2019 13:129

    Content type: Research article

    Published on:

  30. A form of β-glucosidase was isolated and purified from fresh Chrysanthemum morifolium (Ramat.) Tzvel. ‘Boju’ (Boju) and its enzymatic properties explored in this study. The purified enzyme and Boju flavonoids wer...

    Authors: Wei Zhang, Yafeng Zuo, Fengqing Xu, Tongsheng Wang, Jinsong Liu and Deling Wu

    Citation: BMC Chemistry 2019 13:128

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Chemistry 2020 14:16

  31. A series of Schiff bases (3.af) bearing benzimidazole moiety was successfully synthesized in ethanol by refluxing Oct-2-ynoic acid (1,3-dihydrobenzimidazole-2-ylidene)amide with substituted amines. Fourier trans...

    Authors: Thierry Youmbi Fonkui, Monisola Itohan Ikhile, Patrick Berka Njobeh and Derek Tantoh Ndinteh

    Citation: BMC Chemistry 2019 13:127

    Content type: Research article

    Published on:

  32. Research inventories on the co-pyrolysis of major biomass components such as cellulose with amino acid materials is scarce in literature despite the fact that such studies are critical in understanding toxic p...

    Authors: Samuel K. Kirkok, Joshua K. Kibet, Francis Okanga, Thomas Kinyanjui and Vincent Nyamori

    Citation: BMC Chemistry 2019 13:126

    Content type: Research article

    Published on:

  33. In situ analysis of odor is an important approach to connect odor with chemical composition. However, it is difficult to conduct a rapid direct analysis of the odor sample because of low analyte concentration ...

    Authors: Shihao Sun, Yihan Zhang, Peng Li, Hui Xi, Lei Wu, Jianxun Zhang, Guixin Peng and Yue Su

    Citation: BMC Chemistry 2019 13:125

    Content type: Research article

    Published on:

  34. New fluorinated diaryl ethers and bisarylic ketones were designed and evaluated for their anti-inflammatory effects in primary macrophages.

    Authors: Abeer J. Ayoub, Layal Hariss, Nehme El-Hachem, Ghewa A. El-Achkar, Sandra E. Ghayad, Oula K. Dagher, Nada Borghol, René Grée, Bassam Badran, Ali Hachem, Eva Hamade and Aida Habib

    Citation: BMC Chemistry 2019 13:124

    Content type: Research article

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  35. Baricitinib, with a 2-(1-(ethylsulfonyl)azetidin-3-yl)acetonitrile moiety at N-2 position of the pyrazol skeleton, is an oral and selective reversible inhibitor of the JAK1 and JAK2 and displays potent anti-infla...

    Authors: Xin Cui, Junming Du, Zongqing Jia, Xilong Wang and Haiyong Jia

    Citation: BMC Chemistry 2019 13:123

    Content type: Research article

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  36. Current methods of removing organic pollutants from water are becoming ineffective as the world population increases. In this study, a series of biorenewable triblock copolymers with hydrophobic poly(ε-caprola...

    Authors: Katrina T. Bernhardt, Haley G. Collins and Amy M. Balija

    Citation: BMC Chemistry 2019 13:122

    Content type: Research article

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  37. The study aims to develop simple, sensitive, and selective methods for detecting methylphenidate in its bulk, dosage form and human urine. Sensing materials include β-cyclodextrin (β-CD), γ-cyclodextrin (γ-CD)...

    Authors: Haitham AlRabiah, Mohammed Abounassif, Haya I. Aljohar and Gamal Abdel-Hafiz Mostafa

    Citation: BMC Chemistry 2019 13:121

    Content type: Research article

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  38. Crosslinked sulfonated polyacrylamide (Cross-PAA-SO3H) attached to nano-Fe3O4 as a superior catalyst has been used for the synthesis of 3-alkyl-4-phenyl-1,3-thiazole-2(3H)-thione derivatives through a three-compo...

    Authors: Hossein Shahbazi-Alavi, Sheida Khojasteh-Khosro, Javad Safaei-Ghomi and Maryam Tavazo

    Citation: BMC Chemistry 2019 13:120

    Content type: Research article

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  39. The synthesized Fe3O4@l-arginine showed strong catalytic performance in the one-pot synthesis of spiropyranopyrazoles via the reactions of hydrazines, β-keto esters, isatins, and malononitrile or ethyl cyanoaceta...

    Authors: Mohammad Ali Ghasemzadeh, Boshra Mirhosseini-Eshkevari and Mohammad Hossein Abdollahi-Basir

    Citation: BMC Chemistry 2019 13:119

    Content type: Research article

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  40. In the present study two different RSLC columns, Acclaim RSLC 120 C18, 5.0 µm, 4.6 × 150 mm (column A) and Acclaim RSLC 120 C18, 2.2 µm, 2.1 × 100 mm (Column B) were utilized for the analysis of velpatasvir (V...

    Authors: Moustapha Eid Moustapha, Rania Mohamed El-Gamal and Fathalla Fathalla Belal

    Citation: BMC Chemistry 2019 13:118

    Content type: Research article

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  41. The transcription factor Nuclear factor erythroid-2-related factor 2 (NRF2) and its principal repressive regulator, Kelch-like ECH-associated protein 1 (KEAP1), are perilous in the regulation of inflammation, ...

    Authors: Murugesh Kandasamy, Kit-Kay Mak, Thangaraj Devadoss, Punniyakoti Veeraveedu Thanikachalam, Raghavendra Sakirolla, Hira Choudhury and Mallikarjuna Rao Pichika

    Citation: BMC Chemistry 2019 13:117

    Content type: Research article

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  42. Pyrazoles, thiazoles and fused thiazoles have been reported to possess many biological activities. 3-Methyl-5-oxo-4-(2-arylhydrazono)-4,5-dihydro-1H-pyrazole-1-carbothioamides 3a,b (obtained from the reaction of ...

    Authors: Abdelwahed R. Sayed, Sobhi M. Gomha, Fathy M. Abdelrazek, Mohamed S. Farghaly, Shaimaa A. Hassan and Peter Metz

    Citation: BMC Chemistry 2019 13:116

    Content type: Research article

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  43. 2-Aminothiazoles are significant class of organic medicinal compounds utilized as starting material for the synthesis of diverse range of heterocyclic analogues with promising therapeutic roles as antibacteria...

    Authors: Saima Ejaz, Humaira Nadeem, Rehan Zafar Paracha, Sadia Sarwar and Sadaf Ejaz

    Citation: BMC Chemistry 2019 13:115

    Content type: Research article

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  44. Natural Bombyx mori silk fibroin (SF) fibers were modified with 2-methacryloyloxyethyl isocyanate (MOI) first for the introduction of vinyl groups. Then, 1H,1H,2H,2H-perfluorodecanethiol was grafted onto the SF f...

    Authors: Xiaoning Zhang, Jianwei Liang, Zhenyu Chen, Carrie Donley, Yuling Liu and Guotao Cheng

    Citation: BMC Chemistry 2019 13:114

    Content type: Research article

    Published on: