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  1. Content type: Research Article

    Paracetamol (PAR), Pseudoephedrine hydrochloride (PSE) and cetirizine dihydrochloride (CET) is a ternary mixture that composes tablets which are popular for the relief of flu in Egypt. The spectra of the drugs...

    Authors: Souha H. Youssef, Maha Abdel-Monem Hegazy, Dalia Mohamed and Amr Mohamed Badawey

    Citation: Chemistry Central Journal 2018 12:67

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  2. Content type: Research article

    The study describes the synthesis, characterization, in vitro antimicrobial and anticancer evaluation of a series of 2-(1-benzoyl-1H-benzo[d]imidazol-2-ylthio)-N-substituted acetamide derivatives. The synthesized...

    Authors: Snehlata Yadav, Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah, Abhishek Mathur and Balasubramanian Narasimhan

    Citation: Chemistry Central Journal 2018 12:66

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  3. Content type: Research Article

    Doxorubicin hydrochloride (DOX·HCl), an anthracycline glycoside antibiotic, exhibits low oral bioavailability due to active efflux from intestinal P-glycoprotein receptors. The oral administration of DOX remai...

    Authors: Niyaz Ahmad, Rizwan Ahmad, Md Aftab Alam and Farhan Jalees Ahmad

    Citation: Chemistry Central Journal 2018 12:65

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  4. Content type: Research article

    Described a series of main target compounds pyrimido[5,4-e][1,2,4]triazines is obtained via condensation of 6-hydrazinyluracil with different aromatic aldehydes to give the hydrazones followed by nitrosation with...

    Authors: Samar A. El-Kalyoubi

    Citation: Chemistry Central Journal 2018 12:64

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  5. Content type: Research Article

    An efficient one pot method for the synthesis of α-alkoxymethylphosphonium iodides is developed by using PPh3/I2 combination at room temperature. Reaction conditions are found general to synthesize wide range of ...

    Authors: Humaira Yasmeen Gondal, Zain Maqsood Cheema, Javid Hussain Zaidi, Sammer Yousuf and M. Iqbal Choudhary

    Citation: Chemistry Central Journal 2018 12:62

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  6. Content type: Research article

    Masitinib (MST) is an orally administered drug that targets mast cells and macrophages, important cells for immunity, by inhibiting a limited number of tyrosine kinases. It is currently registered in Europe an...

    Authors: Adnan A. Kadi, Sawsan M. Amer, Hany W. Darwish and Mohamed W. Attwa

    Citation: Chemistry Central Journal 2018 12:61

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  7. Content type: Research article

    There is no fluorescence spectroscopic method for the determination of trigonelline and theobromine in green coffee beans. Therefore, the objective of this study was to develop a new fluorescence spectroscopic...

    Authors: Hagos Yisak, Mesfin Redi-Abshiro and Bhagwan Singh Chandravanshi

    Citation: Chemistry Central Journal 2018 12:59

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  8. Content type: Research article

    Radix Glycyrrhizae is the rhizome of Glycyrrhiza inflata Bat., Glycyrrhiza uralensis Fisch. or Glycyrrhiza glabra L. The present paper describes the isolation and the structural elucidation of three new dihydrois...

    Authors: Songsong Zhao, Xinjia Yan, Ying Zhao, Jing Wen, Zhenzhen Zhao and Hongwei Liu

    Citation: Chemistry Central Journal 2018 12:58

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  9. Content type: Review

    Dioscorea nipponica Makino is a perennial twining herbs belonging to the family Dioscoreaceae, which is mainly distributed in the northeastern, northern, eastern and central regions of China. Traditionally, the r...

    Authors: Si-hong Ou-yang, Tao Jiang, Lin Zhu and Tao Yi

    Citation: Chemistry Central Journal 2018 12:57

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  10. Content type: Research Article

    The synthesis of new thiazole derivatives is very important because of their diverse biological activities. Also , many drugs containing thiazole ring in their skeletons are available in the market such as Aba...

    Authors: Yahia N. Mabkhot, Mohammed M. Alharbi, Salim S. Al-Showiman, Hazem A. Ghabbour, Nabila A. Kheder, Saied M. Soliman and Wolfgang Frey

    Citation: Chemistry Central Journal 2018 12:56

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  11. Content type: Research Article

    A series of azinesulfonamide derivatives of long-chain arylpiperazines with variable-length alkylene spacers between sulfonamide and 4-arylpiperazine moiety is designed, synthesized, and biologically evaluated...

    Authors: Krzysztof Marciniec, Rafał Kurczab, Maria Książek, Ewa Bębenek, Elwira Chrobak, Grzegorz Satała, Andrzej J. Bojarski, Joachim Kusz and Paweł Zajdel

    Citation: Chemistry Central Journal 2018 12:55

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  12. Content type: Research article

    A fast method for the identification and stability evaluation of the aggregation pheromone rhynchophorol, which is the main substance used for chemical communication by the beetle Rhynchophorus palmarum L., was v...

    Authors: Arão Cardoso Viana, Ingrid Graça Ramos, Edeilza Lopes dos Santos, Artur José Santos Mascarenhas, Marcos dos Santos Lima, Antônio Euzébio Goulart Sant’Ana and Janice Izabel Druzian

    Citation: Chemistry Central Journal 2018 12:54

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  13. Content type: Research article

    In order to develop new larvicidal agents derived from phytochemicals, the larvicidal activity of fifty molecules that are constituent of essential oils was evaluated against Culex quinquefasciatus Say. Terpenes,...

    Authors: S. Andrade-Ochoa, J. Correa-Basurto, L. M. Rodríguez-Valdez, L. E. Sánchez-Torres, B. Nogueda-Torres and G. V. Nevárez-Moorillón

    Citation: Chemistry Central Journal 2018 12:53

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  14. Content type: Research article

    Psidium guineense, known as Araçá, is a Brazilian botanical resource with commercial application perspectives, based on the functional elements of its fruits and due to the use of its leaves as an anti-inflammato...

    Authors: Pablo Luis B. Figueiredo, Renan C. Silva, Joyce Kelly R. da Silva, Chieno Suemitsu, Rosa Helena V. Mourão and José Guilherme S. Maia

    Citation: Chemistry Central Journal 2018 12:52

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  15. Content type: Research article

    A novel series of substituted 2-thiohydantoin incorporated with benzoimidazole, pyrazole, triazole and/or benzoxazole moieties has been synthesized using (E)-3-[1-(4-bromophenyl)ethylideneamino]-2-thioxoimidazoli...

    Authors: Heba A. Elhady, Refat El-Sayed and Hamedah S. Al-nathali

    Citation: Chemistry Central Journal 2018 12:51

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  16. Content type: Research article

    A series of thiazolopyrimidine derivatives have been synthesized via multicomponent reaction and tested for biological activities. This research aims to develop a new synthetic method of poly fused pyrimidines...

    Authors: Ayman M. S. Youssef, Ahmed M. Fouda and Rasha M. Faty

    Citation: Chemistry Central Journal 2018 12:50

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  17. Content type: Research Article

    Thiophene derivatives have shown versatile pharmacological activities. The Suzuki reaction proved a convenient method for C–C bond formations in organic molecules. In the present research work novel derivative...

    Authors: Komal Rizwan, Muhammad Zubair, Nasir Rasool, Tariq Mahmood, Khurshid Ayub, Noorjahan Banu Alitheen, Muhammad Nazirul Mubin Aziz, Muhammad Nadeem Akhtar, Faiz-ul-Hassan Nasim, Snober Mona Bukhary, Viqar Uddin Ahmad and Mubeen Rani

    Citation: Chemistry Central Journal 2018 12:49

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  18. Content type: Research Article

    To develop and validate a bio-analytical HPLC–MS/MS method for the determination of conivaptan (CVA) an arginine-vasopressin receptor blocker in human plasma and in rat liver microsomes (RLMs).

    Authors: Haitham Alrabiah, Adnan A. Kadi, Mohamed W. Attwa and Gamal A. E. Mostafa

    Citation: Chemistry Central Journal 2018 12:47

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  19. Content type: Research Article

    Electrically conductive polyorthochloroaniline/chromium nanocomposites (POC/Cr NCs) were prepared by in situ chemical oxidative polymerization of orthochloroaniline in the presence of Cr nanoparticles (Cr NPs)...

    Authors: Mirza Nadeem Ahmad, Fakher Rafique, Faisal Nawaz, Tahir Farooq, Muhammad Naveed Anjum, Tajamal Hussain, Sajjad Hassan, Madeeha Batool, Hamad Khalid and Khurram Shehzad

    Citation: Chemistry Central Journal 2018 12:46

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  20. Content type: Research Article

    In this work, a novel aptamer-based electrochemical biosensor was developed for the determination of Ochratoxin A (OTA) by using carbon aerogels (CAs) and methylene blue (MB) as signal amplification strategy. ...

    Authors: Min Wei and Wenyang Zhang

    Citation: Chemistry Central Journal 2018 12:45

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  21. Content type: Research article

    In this paper, a series of poly ammonium shale inhibitors were prepared from diethylamine, epichlorohydrin, and melamine (DEM) and their inhibition to shale were evaluated by bentonite linear expansion test, a...

    Authors: Li Zhang, Tiehu Li, Lei Huang, Zhengqin Ye, Zhongbin Ye, Xin Yan, Lili Li, Qiang Deng, Gang Chen, Jie Zhang and Zhifang Zhang

    Citation: Chemistry Central Journal 2018 12:44

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  22. Content type: Research Article

    Food flavor appreciation is one of the first signals along with food appearance and texture encountered by consumers during eating of food. Also, it is well known that flavor can strongly influence consumer’s ...

    Authors: Ola Lasekan, Megala Muniady, Mee Lin and Fatma Dabaj

    Citation: Chemistry Central Journal 2018 12:43

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  23. Content type: Research Article

    In our present investigation, synthesis of nontoxic, eco friendly and cost effective silver nanoparticles, Phyllanthus acidus (P. acidus) was used as starting material. The influence of phyto-constituents present...

    Authors: Cherukuri Sowmya, Vuppalapati Lavakumar, Narayanan Venkateshan, Velayutham Ravichandiran and D. V. R. Saigopal

    Citation: Chemistry Central Journal 2018 12:42

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  24. Content type: Research article

    Lung cancer is the notable cause of cancer associated deaths worldwide. Recent studies revealed that the expression of matrix metalloproteinases (MMPs) is extremely high in lung tumors compared with non-malign...

    Authors: Dharmender Rathee, Viney Lather, Ajmer Singh Grewal and Harish Dureja

    Citation: Chemistry Central Journal 2018 12:41

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  25. Content type: Research Article

    The quality of material medicine resources has had a considerable impact on the development of the health industry, which has created a bottleneck for traditional Chinese medicine (TCM). Dendrobium officinale, wh...

    Authors: Chunhua Zhou, Zhenshan Xie, Zhouxi Lei, Yuechun Huang and Gang Wei

    Citation: Chemistry Central Journal 2018 12:40

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  26. Content type: Research Article

    Nowadays the industrial chemistry reactions rely on green technologies. Enzymes as lipases are increasing its use in diverse chemical processes. Epoxidized fatty acid methyl esters obtained from transesterific...

    Authors: Alejandro Sustaita-Rodríguez, Víctor H. Ramos-Sánchez, Alejandro A. Camacho-Dávila, Gerardo Zaragoza-Galán, José C. Espinoza-Hicks and David Chávez-Flores

    Citation: Chemistry Central Journal 2018 12:39

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  27. Content type: Review

    Heterocyclic compounds offer a high degree of structural diversity and have proven to be broadly and economically useful as therapeutic agents. Comprehensive research on diverse therapeutic potentials of heter...

    Authors: Sanjiv Kumar and Balasubramanian Narasimhan

    Citation: Chemistry Central Journal 2018 12:38

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  28. Content type: Research Article

    The oxidation of cyclohexane under mild conditions occupies an important position in the chemical industry. A few soluble transition metals were widely used as homogeneous catalysts in the industrial oxidation...

    Authors: Yun Hong, Dalei Sun and Yanxiong Fang

    Citation: Chemistry Central Journal 2018 12:36

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  29. Content type: Review

    An organic compound known as 5-hydroxymethylfurfural (HMF) is formed from reducing sugars in honey and various processed foods in acidic environments when they are heated through the Maillard reaction. In addi...

    Authors: Ummay Mahfuza Shapla, Md. Solayman, Nadia Alam, Md. Ibrahim Khalil and Siew Hua Gan

    Citation: Chemistry Central Journal 2018 12:35

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  30. Content type: Research Article

    Eugenol is the major component of clove essential oil and has demonstrated relevant biological potential with well-known antimicrobial and antioxidant action. Therefore, this work carried out the synthesis, pu...

    Authors: Francisco Felipe Maia da Silva, Francisco José Queiroz Monte, Telma Leda Gomes de Lemos, Patrícia Georgina Garcia do Nascimento, Alana Kelly de Medeiros Costa and Luanda Misley Mota de Paiva

    Citation: Chemistry Central Journal 2018 12:34

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  31. Content type: Research Article

    Flunarizine dihydrochloride (FLN) is used in the prophylactic treatment of migraine, vertigo, occlusive peripheral vascular disease and epilepsy. Cyclodextrins (CDs) are chiral, truncated cone shaped macrocycl...

    Authors: Santosh Kumar Upadhyay and Syed Mashhood Ali

    Citation: Chemistry Central Journal 2018 12:33

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  32. Content type: Research article

    Quantitative structure–activity relationship (QSAR) was carried out to study a series of aminooxadiazoles as PIM1 inhibitors having pki ranging from 5.59 to 9.62 (k i in nM)...

    Authors: Adnane Aouidate, Adib Ghaleb, Mounir Ghamali, Samir Chtita, Abdellah Ousaa, M’barek Choukrad, Abdelouahid Sbai, Mohammed Bouachrine and Tahar Lakhlifi

    Citation: Chemistry Central Journal 2018 12:32

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  33. Content type: Research Article

    Curcumin is one of the leading compound extracted from the dry powder of Curcuma longa (Zingiberaceae family), which possess several pharmacological properties. However, in vivo administration exhibited limited a...

    Authors: Siti Noor Hajar Zamrus, Muhammad Nadeem Akhtar, Swee Keong Yeap, Ching Kheng Quah, Wan-Sin Loh, Noorjahan Banu Alitheen, Seema Zareen, Saiful Nizam Tajuddin, Yazmin Hussin and Syed Adnan Ali Shah

    Citation: Chemistry Central Journal 2018 12:31

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  34. Content type: Research article

    Preservative effect of melanin-free extract of Sepia esculenta ink (MFESI) on Sparus latus fillet has been verified in our previous work. This study aims to further approach the mechanism of MFESI for extending t...

    Authors: Zhen-Hua Duan, Hua-Zhong Liu, Ping Luo, Yi-Peng Gu and Yan-Qun Li

    Citation: Chemistry Central Journal 2018 12:30

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  35. Content type: Research Article

    Design and synthesis of pyrazole-dimedone derivatives were described by one-pot multicomponent reaction as new antimicrobial agents. These new molecular framework were synthesized in high yields with a broad s...

    Authors: Assem Barakat, Abdullah M. Al-Majid, Bander M. Al-Qahtany, M. Ali, Mohamed Teleb, Mohamed H. Al-Agamy, Sehrish Naz and Zaheer Ul-Haq

    Citation: Chemistry Central Journal 2018 12:29

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  36. Content type: Research article

    This study explores the potential application of rice bran (agro waste) to nano-encapsulate phytase, which is a thermally unstable biologically active enzyme. Rice bran was converted to nanofibers (20–50 nm in...

    Authors: Upendra A. Rathnayake, Tharindu Senapathi, Chanaka Sandaruwan, Sanja Gunawardene, Veranja Karunaratne and Nilwala Kottegoda

    Citation: Chemistry Central Journal 2018 12:28

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  37. Content type: Research article

    A gas chromatography–mass spectrometry (GC–MS) method was validated for the determination of 16 polycyclic aromatic hydrocarbons (PAHs) from the FDA list of 93 harmful or potentially harmful constituents of ma...

    Authors: Jana Jeffery, Maria Carradus, Karolina Songin, Michael Pettit, Karl Pettit and Christopher Wright

    Citation: Chemistry Central Journal 2018 12:27

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  38. Content type: Research Article

    A set of different donor-π-acceptor compounds having dicyanovinyl as the acceptor and aryl moieties as donors were synthesized by Knoevenagel condensation. The UV–visible absorption and fluorescence spectra we...

    Authors: Mohie E. M. Zayed, Reda M. El-Shishtawy, Shaaban A. Elroby, Khalid O. Al-Footy and Zahra M. Al-amshany

    Citation: Chemistry Central Journal 2018 12:26

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  39. Content type: Research Article

    Apart from its numerous biological activities like antidiabetic, anti-inflammatory, antimicrobial, pyrazine moiety plays an important role in luminescent materials. Its role in luminescent materials is due to ...

    Authors: Mushtaq Ahmad, Zahida Perveen, Adailton J. Bortoluzzi, Shahid Hameed, Muhammad R. Shah, Muhammad Tariq, Ghias ud Din, Muhammad T. Jan, Muhammad Siddique and Muhammad Anwar

    Citation: Chemistry Central Journal 2018 12:25

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  40. Content type: Research

    Complexes of imidazole derivatives with transition metal ions have attracted much attention because of their biological and pharmacological activities, such as antimicrobial, antifungal, antiallergic, antitumo...

    Authors: Assila Maatar Ben Salah, Lilia Belghith Fendri, Thierry Bataille, Raquel P. Herrera and Houcine Naïli

    Citation: Chemistry Central Journal 2018 12:24

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  41. Content type: Research Article

    In this study, the contents of myricetrin, quercitrin and afzelin in Cercis chinensis leaves were determined simultaneously by 1-butyl-3-methylimidazolium tetrafluoroborate [BMIM] BF4/70% ethanol microextraction ...

    Authors: Mengjun Shi, Nan He, Wenjing Li, Changqin Li and Wenyi Kang

    Citation: Chemistry Central Journal 2018 12:23

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  42. Content type: Research Article

    In general, the greater the number of directly linked nitrogen atoms in a molecule, the better its energetic performance, while the stability will be accordingly lower. But 1,1ʹ-azobis-1,2,3-triazole (1) and 4,4ʹ...

    Authors: Chenhui Jia, Yuchuan Li, Shujuan Zhang, Teng Fei and Siping Pang

    Citation: Chemistry Central Journal 2018 12:22

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  43. Content type: Research Article

    The molecular docking method was used to calculate the binding free energies between biphenyl dioxygenase and 209 polychlorinated biphenyl (PCB) congeners. The relationships between the calculated binding free...

    Authors: Xiao-Hui Zhao, Xiao-Lei Wang and Yu Li

    Citation: Chemistry Central Journal 2018 12:20

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  44. Content type: Research Article

    The molecularly imprinted polymers for gallic acid were synthesized by precipitation polymerization. During the process of synthesis a non-covalent approach was used for the interaction of template and monomer...

    Authors: Showkat Ahmad Bhawani, Tham Soon Sen and Mohammad Nasir Mohammad Ibrahim

    Citation: Chemistry Central Journal 2018 12:19

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  45. Content type: Research Article

    Clean water, which is free from pathogens and toxic chemicals, is vital to human health. The blue planet is encountering remarkable challenges in meeting the ever-increasing demands of clean water. The intenti...

    Authors: H. D. A. Chathumal Jayaweera, Induni Siriwardane, K. M. Nalin de Silva and Rohini M. de Silva

    Citation: Chemistry Central Journal 2018 12:18

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