Althagafi I, Farghaly TA, Abbas EMH, Harras MF. Benzosuberone as precursor for synthesis of antimicrobial agents: synthesis, antimicrobial activity, and molecular docking. Polycycl Aromat Compd. 2021;41(8):1646–66.
Article
CAS
Google Scholar
Kumar H, Kumar P, Narasimhan B, Ramasamy K, Mani V, Mishra RK, et al. Synthesis, in vitro antimicrobial, antiproliferative, and QSAR studies of N-(substituted phenyl)-2/4-(1H-indol-3-ylazo)-benzamides. Med Chem Res. 2013;22:1957–71.
Article
CAS
Google Scholar
Zamperini C, Maccari G, Deodato D, Pasero C, D’Agostino I, Orofino F, et al. Identification, synthesis and biological activity of alkyl-guanidine oligomers as potent antibacterial agents. Sci Rep. 2017;7:8251.
Article
CAS
Google Scholar
Keche AP, Hatnapure GD, Tale RH, Rodge AH, Birajdar SS, Kamble VM. Novel pyrimidine derivatives with aryl urea, thiourea and sulfonamide moieties: synthesis, anti-infammatory and antimicrobial evaluation. Bioorg Med Chem Lett. 2012;22(10):3445–8.
Article
CAS
Google Scholar
Sharma D, Kumar S, Narasimhan B, Ramasamy K, Lim SM, Shah SAA, et al. 4-(4-Bromophenyl)-thiazol-2-amine derivatives: synthesis, biological activity and molecular docking study with ADME profile. BMC Chem. 2019;13:60.
Article
Google Scholar
Sharma D, Kumar S, Narasimhan B, Ramasamy K, Lim SM, Shah SAA, et al. Synthesis, molecular modelling and biological significance of N-(4-(4-bromophenyl)thiazol-2-yl)-2-chloroacetamide derivatives as prospective antimicrobial and antiproliferative agents. BMC Chem. 2019;13:46.
Article
Google Scholar
Tahlan S, Kumar S, Ramasamy K, Lim SM, Ali Shah SA, Vasudevan M, et al. In-silico molecular design of heterocyclic benzimidazole scaffolds as prospective anticancer agents. BMC Chem. 2019;13:90.
Article
Google Scholar
Trotsko N, Kosikowska U, Paneth A, Plech T, Malm A, Wujec M. Synthesis and antibacterial activity of new thiazolidine-2,4-dione-based chlorophenylthiosemicarbazone hybrids. Molecules. 2018;23(5):1023.
Article
Google Scholar
Parekh NM, Juddhawala KV, Rawal BM. Antimicrobial activity of thiazolyl benzene sulfonamide-condensed 2,4-thiazolidinediones derivatives. Med Chem Res. 2012;22:2737–45.
Article
Google Scholar
Jiang B, Luo J, Guo S, Wang L. Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties. Bioorg Chem. 2021;108: 104648.
Article
CAS
Google Scholar
Fettach S, Thari FZ, Hafidi Z, Karrouchi K, Bouathmany K, Cherrah Y, et al. Biological, toxicological and molecular docking evaluations of isoxazoline-thiazolidine-2,4-dione analogues as new class of anti-hyperglycemic agents. J Biomol Struct Dyn. 2021. https://doi.org/10.1080/07391102.2021.2017348.
Article
PubMed
Google Scholar
Mohd Siddique MU, Thakur A, Shilkar D, Yasmin S, Halakova D, Kovacikova L, et al. Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives. Eur J Med Chem. 2021;223: 113630.
Article
CAS
Google Scholar
Abdellatif KRA, Fadaly WAA, Kamel GM, Elshaier YAMM, El-Magd MA. Design, synthesis, modeling studies and biological evaluation of thiazolidine derivatives containing pyrazole core as potential anti-diabetic PPAR-γ agonists and anti-inflammatory COX-2 selective inhibitors. Bioorg Chem. 2019;82:86–99.
Article
CAS
Google Scholar
Elkamhawy A, Kim NY, Hassan AHE, Park JE, Paik S, Yang JE, et al. Thiazolidine-2,4-dione-based irreversible allosteric IKK-β kinase inhibitors: optimization into in vivo active anti-inflammatory agents. Eur J Med Chem. 2020;188:111955.
Article
CAS
Google Scholar
Asati V, Bajaj S, Mahapatra DK, Bharti SK. Molecular modeling studies of some thiazolidine-2,4-dione derivatives as 15-PGDH inhibitors. Med Chem Res. 2015;25(1):94–108.
Article
Google Scholar
Yu I, Choi D, Lee HK, Cho H. Synthesis and biological evaluation of new benzylidenethiazolidine-2,4-dione derivatives as 15-hydroxyprostaglandin dehydrogenase inhibitors to control the intracellular levels of prostaglandin E2 for wound healing. Biotechnol Bioprocess Eng. 2019;24(3):464–75.
Article
CAS
Google Scholar
Ibrahim HS, Abdelsalam M, Zeyn Y, Zessin M, Mustafa AHM, Fischer MA, et al. Synthesis, molecular docking and biological characterization of pyrazine linked 2-aminobenzamides as new class i selective histone deacetylase (hdac) inhibitors with anti-leukemic activity. Int J Mol Sci. 2022;23:369.
Article
CAS
Google Scholar
El-Kashef H, Badr G, Abo El-Maali N, Sayed D, Melnyk P, Lebegue N, et al. Synthesis of a novel series of (Z)-3,5-disubstituted thiazolidine-2,4-diones as promising anti-breast cancer agents. Bioorg Chem. 2020;96: 103569.
Article
CAS
Google Scholar
Sharma RK, Younis Y, Mugumbate G, Njoroge M, Gut J, Rosenthal PJ, et al. Synthesis and structure activity-relationship studies of thiazolidinediones as antiplasmodial inhibitors of the Plasmodium falciparum cysteine protease falcipain-2. Eur J Med Chem. 2015;90:507–18.
Article
CAS
Google Scholar
Ratnaparkhi H, Thakar S, Bansode D. An overview of chemistry and antitubercular activity of thiazolidinediones. Sch Acad J Pharm. 2020;9(1):23–31.
Article
CAS
Google Scholar
Trotsko N, Golus J, Kazimierczak P, Paneth A, Przekora A, Ginalska G, et al. Synthesis and antimycobacterial activity of thiazolidine-2,4-dione based derivatives with halogenbenzohydrazones and pyridinecarbohydrazones substituents. Eur J Med Chem. 2020;189: 112045.
Article
CAS
Google Scholar
Mohammed Iqbal AK, Khan AY, Kalashetti MB, Belavagi NS, Gong YD, Khazi IAM. Synthesis, hypoglycemic and hypolipidemic activities of novel thiazolidinedione derivatives containing thiazole/triazole/oxadiazole ring. Eur J Med Chem. 2012;53:308–15.
Article
CAS
Google Scholar
Bahare RS, Ganguly S, Choowongkomon K, Seetaha S. Synthesis, HIV-1 RT inhibitory, antibacterial, antifungal and binding mode studies of some novel N-substituted 5-benzylidine-2, 4-thiazolidinediones. DARU J Pharm Sci. 2015;23(1):6.
Article
Google Scholar
Aziz HA, El-Saghier AMM, Badr M, Abuo-Rahma GEDA, Shoman ME. Thiazolidine-2,4-dione-linked ciprofloxacin derivatives with broad-spectrum antibacterial, MRSA and topoisomerase inhibitory activities. Mol Divers. 2021. https://doi.org/10.1007/s11030-021-10302-7.
Article
PubMed
Google Scholar
Alegaon SG, Venkatasubramanian U, Alagawadi KR, Kumar D, Kavalapure RS, Ranade SD, et al. Synthesis, molecular docking and ADME studies of thiazole-thiazolidinedione hybrids as antimicrobial agents. J Biomol Struct Dyn. 2021. https://doi.org/10.1080/07391102.2021.1880479.
Article
PubMed
Google Scholar
Moorthy P, Ekambaram SP, Perumal SS. Synthesis, characterization and antimicrobial evaluation of imidazolyl thiazolidinedione derivatives. Arab J Chem. 2019;12(3):413–9.
Article
CAS
Google Scholar
Kumar H, Deep A, Marwaha RK. Design, synthesis, in silico studies and biological evaluation of 5-((E)-4-((E)-(substituted aryl/alkyl)methyl)benzylidene)thiazolidine-2,4-dione derivatives. BMC Chem. 2020;14:25.
Article
Google Scholar
Sameeh MY, Khowdiary MM, Nassar HS, Abdelall MM, Alderhami SA, Elhenawy AA. Discovery potent of thiazolidinedione derivatives as antioxidant, α-amylase inhibitor and antidiabetic agent. Biomedicines. 2022;10:24.
Article
CAS
Google Scholar
Wang J, Urban L, Bojanic D. Maximising use of in vitro ADMET tools to predict in vivo bioavailability and safety. Expert Opin Drug Metab Toxicol. 2007;3(5):641–65.
Article
CAS
Google Scholar
Gleeson MP, Hersey A, Hannongbua S. In-Silico ADME Models: a general assessment of their utility in drug discovery applications. Curr Top Med Chem. 2011;11(4):358–81.
Article
CAS
Google Scholar
Li AP. Screening for human ADME/Tox drug properties in drug discovery. Res Focus. 2001;6(7):357–66.
CAS
Google Scholar
Cappuccino JC, Sherman N. Microbiology—a laboratory manual. California: Addison Wesley; 1999. p. 263.
Google Scholar
Nyaki HY, Mahmoodi NO. Synthesis and characterization of derivatives including thiazolidine-2,4-dione/1-H- imidazole and evaluation of antimicrobial, antioxidant, and cytotoxic properties of new synthetic heterocyclic compounds. Res Chem Intermed. 2021;47:4129–55.
Article
CAS
Google Scholar
Mardani-Ghahfarokhi A, Farhoosh R. Antioxidant activity and mechanism of inhibitory action of gentisic and α-resorcylic acids. Sci Rep. 2020;10:19487.
Article
CAS
Google Scholar
Redon J, Oliva MR, Tormos C, Giner V, Chaves J, Iradi A, et al. Antioxidant activities and oxidative stress by products in human hypertension. J Hypertens. 2003;1(1):1096–109.
Article
Google Scholar
QikProp, Schrödinger, LLC, New York, NY, 2020.
Kumar S, Lim SM, Ramasamy K, Vasudevan M, Ali Shah SA, Selvaraj M, et al. Synthesis, molecular docking and biological evaluation of bis-pyrimidine Schiff base derivatives. Chem Cent J. 2017;11:89.
Article
Google Scholar
Deep A, Jain S, Sharma PC, Mittal SK, Phogat P, Malhotra M. Synthesis, characterization and antimicrobial evaluation of 2,5-disubstituted-4-thiazolidinone derivatives. Arab J Chem. 2014;7:287–91.
Article
CAS
Google Scholar
Pharmacopoeia of India, vol.-Ӏ. New Delhi: Controller of publication, ministry of health department, Govt. of India; 2007. p. 37.
Koppireddi S, Komsani JR, Avula S, Pombala S, Vasamsetti S, Kotamraju S, et al. Novel 2-(2,4-dioxo-1,3-thiazolidin-5-yl)acetamides as antioxidant and/or anti-inflammatory compounds. Eur J Med Chem. 2013;66:305–13.
Article
CAS
Google Scholar
Joseph A, Shah CKS, Kumar SS, Alex AT, Maliyakkal N, Moorkoth S, et al. Synthesis, in vitro anticancer and antioxidant activity of thiadiazole substituted thiazolidin-4-ones. Acta Pharm. 2013;63:397–408.
Article
CAS
Google Scholar