Synthesis, biological evaluation and in-silico ADME studies of novel series of thiazolidin-2,4-dione derivatives as antimicrobial, antioxidant and anticancer agents

Table 3 In vitro antioxidant activity of the synthesized compounds

Comp.	% Inhibition				Antioxidant activity (IC₅₀ = µg/mL)
Comp.	25 µg/mL	50 µg/mL	75 µg/mL	100 µg/mL	Antioxidant activity (IC₅₀ = µg/mL)
H1	21.18	38.03	50.98	63.92	29.58
H2	36.86	43.92	49.80	56.47	29.99
H3	27.45	43.13	56.86	62.74	27.04
H4	15.68	36.47	45.88	56.07	33.78
H5	43.92	56.08	67.84	76.08	14.85
H6	40.78	52.94	61.57	72.16	18.32
H7	29.02	48.63	62.35	68.24	23.43
H8	21.18	40.78	55.69	63.53	28.31
H9	36.86	42.35	54.90	72.94	23.53
H10	27.84	48.24	60.39	66.27	24.46
H11	32.55	43.14	51.76	59.61	28.60
H12	23.53	47.84	57.25	67.45	25.69
H13	21.96	32.16	48.24	60.39	32.09
H14	9.41	21.96	40.00	47.45	35.31
H15	12.94	29.80	44.71	50.98	36.93
H16	32.16	41.96	48.24	64.31	28.24
H17	22.35	32.16	52.55	58.82	31.57
H18	9.41	26.27	36.86	52.55	38.37
H19	36.47	48.63	60.39	65.49	22.22
Ascorbic Acid	16.08	30.20	40.39	48.62	40

ISSN: 2661-801X