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  1. Nitrogen containing heterocycles are widely used and investigated by pharmaceutical industry, as they are important in discovery and designing of new drug molecules. Drugs with a benzimidazole nucleus possess ...

    Authors: Sumit Tahlan, Sanjiv Kumar, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Vasudevan Mani, Ranjana Pathania and Balasubramanian Narasimhan

    Citation: BMC Chemistry 2019 13:50

    Content type: Research article

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  2. In search of new antimicrobial and cytotoxic agents, a series of new naphthol diazenyl scaffold based Schiff bases (NS1NS23) was efficiently synthesized by condensation of 2-hydroxy naphthaldehyde azo dyes with ...

    Authors: Harmeet Kaur, Jasbir Singh and Balasubramanian Narasimhan

    Citation: BMC Chemistry 2019 13:49

    Content type: Research article

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  3. Pyrazolines show different biological activities. In recent years, interest in the chemistry of hydrazonoyl halides has been renewed. 1,3,4-Thiadiazoles are one of the most common heterocyclic pharmacophores w...

    Authors: Abdou O. Abdelhamid, Ibrahim E. El Sayed, Yasser H. Zaki, Ahmed M. Hussein, Mangoud M. Mangoud and Mona A. Hosny

    Citation: BMC Chemistry 2019 13:48

    Content type: Research article

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  4. The medicinal plant Tirpitzia sinensis has been used by the Zhuang ethnic people in mountainous areas of Southwest China to stop bleeding, invigorate blood circulation, and treat inflammation and wounds. In order...

    Authors: Ronghui Gu, Yuehu Wang, Shibiao Wu, Yeling Wang, Ping Li, Li Xu, Yue Zhou, Ze’e Chen, Edward J. Kennelly and Chunlin Long

    Citation: BMC Chemistry 2019 13:47

    Content type: Research article

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  5. To combat the antimicrobial and anticancer drug resistance by pathogens and cancerous cells, efforts has been made to study the pharmacological activities of newly synthesized N-(4-(4-bromophenyl)thiazol-2-yl)-2-...

    Authors: Deepika Sharma, Sanjiv Kumar, Balasubramanian Narasimhan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah and Vasudevan Mani

    Citation: BMC Chemistry 2019 13:46

    Content type: Research article

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  6. Urease are responsible for several pathogenic states in human as well as in animals and its inhibition is utmost urgent. Clinically used drugs are associated with many side effects; recently several researches...

    Authors: Ritu Kataria and Anurag Khatkar

    Citation: BMC Chemistry 2019 13:45

    Content type: Research article

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  7. The existence of heavy metals and coliform bacteria contaminants in aquatic system of Akaki river basin, a sub city of Addis Ababa, Ethiopia has become a public concern as human population increases and land d...

    Authors: Feleke Terefe Fanta, Amare Aregahegn Dubale, Dawit Firemichael Bebizuh and Minaleshewa Atlabachew

    Citation: BMC Chemistry 2019 13:44

    Content type: Research article

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  8. The increased multidrug resistance among antimalarial drugs produces the urgency of potent anti malarial to combat resistant malaria and the malaria burden worldwide. The protein which may prevent the growth o...

    Authors: Jagbir Singh, Rani Mansuri, Sonam Vijay, Ganesh Chandra Sahoo, Arun Sharma and Mahesh Kumar

    Citation: BMC Chemistry 2019 13:43

    Content type: Research article

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  9. The present study reveals the robust and facile methodology for the synthesis of massively selective dispiro-3-phenylpyrrolothiazole hybrids via one-pot 1,3-dipolar cycloaddition reaction by environmentally su...

    Authors: Govindasami Periyasami, Karuppiah Ponmurugan, Natarajan Arumugam, Raju Sureshkumar, Mostafizur Rahaman, Durairaju Periyan, Naif Abdullah Al-Dhabi, Shaykha Alzahly and Ali Aldalbahi

    Citation: BMC Chemistry 2019 13:42

    Content type: Research article

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  10. Plants have always played important role in treating human and animal diseases as a therapeutic agent for traditional medicine. Through extensive research throughout the world, potential of natural products ha...

    Authors: Ritu Kataria and Anurag Khatkar

    Citation: BMC Chemistry 2019 13:41

    Content type: Research article

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  11. A facile and convenient method for the synthesis of acridines and its derivatives was developed through one-pot, three-component condensation reaction of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione, ...

    Authors: M. Mujahid Alam, Ahmed T. Mubarak, Mohammed A. Assiri, S. Merajuddin Ahmed and Ahmed M. Fouda

    Citation: BMC Chemistry 2019 13:40

    Content type: Research article

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  12. A convenient approach for (1E,3E)-1,4-diarylbuta-1,3-dienes via intermolecular Heck reaction of olefins and β-bromostyrenes promoted by μ-OMs palladium–dimer complex has been successfully developed. The products ...

    Authors: Xueliang Zhou, Yuan Zhou, Qiang Zhu, Huimin Chen, Nan Wu, Xiangru Wen and Zhou Xu

    Citation: BMC Chemistry 2019 13:39

    Content type: Research article

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  13. Natural based inhibitors of monoamine oxidase are promising drug candidates for the treatment of several neurodegenerative and neuropsychological disorders including depression, anxiety, Parkinson’s disease an...

    Authors: Priyanka Dhiman, Neelam Malik and Anurag Khatkar

    Citation: BMC Chemistry 2019 13:38

    Content type: Research article

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  14. Thiazole is a core structural motif presents in a wide range of natural products. Thiazole derivatives also have a wide range of medicinal and biological properties.

    Authors: Mona A. Hosny, Yasser H. Zaki, Wafaa A. Mokbel and Abdou O. Abdelhamid

    Citation: BMC Chemistry 2019 13:37

    Content type: Research article

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  15. Herein, 2-(2-methoxyphenoxy)-1-phenylethanol (β-O-4), 2-methoxyphenyl anisole (α-O-4) and 4-phenoxyphenol (4-O-5) were selected as typical lignin model compounds. Given the effectiveness of traditional acid–base ...

    Authors: J. Guo, Yu L. Ma, Jia Y. Yu, Yu J. Gao, Ning X. Ma and Xiao Y. Wu

    Citation: BMC Chemistry 2019 13:36

    Content type: Research article

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  16. 4-Thiazolidinone ring is reported to have almost all types of biological activities. Also, it present in many marketed drugs.

    Authors: Yahia N. Mabkhot, Mohammed M. Alharbi, Salim. S. Al-Showiman, Saied M. Soliman, Nabila A. Kheder, Wolfgang Frey, Abdulrhman Asayari, Abdullatif Bin Muhsinah and H. Algarni

    Citation: BMC Chemistry 2019 13:35

    Content type: Research article

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  17. penta-1,4-diene-3-one oxime ether and quinazolin-4(3H)-one derivatives possess favorable agricultural activities. Aiming to discover novel molecules with highly-efficient agricultural activities, a series of pent...

    Authors: Lijuan Chen, Xiaobin Wang, Xu Tang, Rongjiao Xia, Tao Guo, Cheng Zhang, Xiangyang Li and Wei Xue

    Citation: BMC Chemistry 2019 13:34

    Content type: Research article

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  18. Functionalized copolymers were synthesized and are proposed as hosts of RNA. The copolymers are based on carboxymethyl cellulose and poly-(ethylene glycol)-OH. These copolymers were functionalized with two ami...

    Authors: Magali Hernández, Gerardo Leyva, Jonathan J. Magaña, Ariel Guzmán-Vargas, Carlos Felipe, Víctor Lara and Enrique Lima

    Citation: BMC Chemistry 2019 13:33

    Content type: Research article

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  19. Plants either in raw form or their isolated bioactive constituents are utilized as complementary and alternative medicine in various disorders. The present study was designed to evaluate chief phytochemical co...

    Authors: Riffat Batool, Muhammad Rashid Khan, Moniba Sajid, Saima Ali and Zartash Zahra

    Citation: BMC Chemistry 2019 13:32

    Content type: Research article

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  20. AlN films were deposited on Si substrates using a reactive RF magnetron sputtering process and then the films were annealed by using different laser powers and wavelengths (355 nm, 532 nm and 1064 nm). For all...

    Authors: H. K. Lin, Y. J. Huang, W. C. Shih, Y. C. Chen and W. T. Chang

    Citation: BMC Chemistry 2019 13:30

    Content type: Research article

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  21. Priming is a valuable, facile and well-established technique used to enhance seed quality to achieve rapid germination, establishment of stress resistance and improvement of crop yields. Different natural and ...

    Authors: Arruje Hameed, Amjad Hameed, Tahir Farooq, Razia Noreen, Sadia Javed, Shaheera Batool, Ashfaq Ahmad, Tahsin Gulzar and Matloob Ahmad

    Citation: BMC Chemistry 2019 13:29

    Content type: Research article

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  22. The occurrence of emerging pollutants like pharmaceuticals and related compounds in the aquatic and terrestrial environments is of increasing concern. Ciprofloxacin is one of the pharmaceuticals which is activ...

    Authors: Teshome Gezahegn, Bisratewongel Tegegne, Feleke Zewge and Bhagwan Singh Chandravanshi

    Citation: BMC Chemistry 2019 13:28

    Content type: Research article

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  23. Lychee pericarp is rich in phenolic and has good antioxidant activity. The effects of simulated gastric (SGF) and intestinal fluid (SIF) digestion on the contents, composition, and antioxidant activities of th...

    Authors: Qingzhu Zeng, Zhuohui Xu, Mingrui Dai, Xuejiao Cao, Xiong Xiong, Shan He, Yang Yuan, Mingwei Zhang, Lihong Dong, Ruifen Zhang and Dongxiao Su

    Citation: BMC Chemistry 2019 13:27

    Content type: Research article

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  24. The molecular structure of the 2-(4-oxo-3-phenylthiazolidin-2-ylidene) malononitrile (3) is calculated using DFT B3LYP/6-311G(d, p) method. The calculated geometric parameters are in good agreement with the exper...

    Authors: Yahia N. Mabkhot, Salim S. Al-Showiman, A. Barakat, S. M. Soliman, Nabila A. Kheder, Mohammed M. Alharbi, Abdulrahman Asayari, Abdullatif Bin Muhsinah, Asad Ullah and Syed Lal Badshah

    Citation: BMC Chemistry 2019 13:25

    Content type: Research article

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  25. Mangroves plants and their endophytes represent a natural source of novel and bioactive compounds. In our ongoing research on mangrove endophytes from the Panamanian Pacific Coast, we have identified several b...

    Authors: Dioxelis Lopéz, Lilia Cherigo, Luis C. Mejia, Marco A. Loza-Mejía and Sergio Martínez-Luis

    Citation: BMC Chemistry 2019 13:22

    Content type: Research article

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  26. Proanthocyanidin (PAC) is a promising compound that has displayed its potent antineoplastic properties with a specific intrinsic pathway. This precise us to explore the phyto-preventive effect of PAC against c...

    Authors: Mani Suganya, Balasubramanian Mythili Gnanamangai, Balasubramani Ravindran, Soon Woong Chang, Arokiyaraj Selvaraj, Chandramohan Govindasamy, Mohamed Farouk Elsadek and Ponnusamy Ponmurugan

    Citation: BMC Chemistry 2019 13:21

    Content type: Research article

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  27. Measuring concentrations of metabolites of estradiol and progesterone in urine, instead of measuring serum concentrations, is common in research and also is used in patient care. The primary aim of this study ...

    Authors: Mark Newman, Suzanne M. Pratt, Desmond A. Curran and Frank Z. Stanczyk

    Citation: BMC Chemistry 2019 13:20

    Content type: Methodology article

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  28. For the first time, the design and preparation of magnetic polyvinyl alcohol (Fe3O4@PVA) nanocomposite film as a novel nanocatalyst was accomplished by in situ precipitation method. To enhance the catalysis activ...

    Authors: Ali Maleki, Maryam Niksefat, Jamal Rahimi and Zoleikha Hajizadeh

    Citation: BMC Chemistry 2019 13:19

    Content type: Research article

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  29. Titanium dioxide (TiO2) is added in sunscreens due to its ability to absorb ultraviolet (UV) light. However, upon irradiation of UV light, reactive oxygen species particularly hydroxyl radical which can damage hu...

    Authors: Mohamad Nasir Mohamad Ibrahim, Anwar Iqbal, Chai Chuan Shen, Showkat Ahmad Bhawani and Farook Adam

    Citation: BMC Chemistry 2019 13:17

    Content type: Research article

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  30. Indole based thiadiazole derivatives (122) have synthesized, characterized by NMR and HREI-MS and evaluated for β-Glucuronidase inhibition. All compounds showed outstanding β-glucuronidase activity with IC50 val...

    Authors: Noor Barak Almandil, Muhammad Taha, Mohammed Gollapalli, Fazal Rahim, Mohamed Ibrahim, Ashik Mosaddik and El Hassane Anouar

    Citation: BMC Chemistry 2019 13:14

    Content type: Research article

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  31. Dihydrofolate reductase (DHFR) is an important target for antimetabolite class of antimicrobials because it participates in purine synthesis. 2-mercaptobenzimidazole (2MBI) has similar structural features as p...

    Authors: Sumit Tahlan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Vasudevan Mani and Balasubramanian Narasimhan

    Citation: BMC Chemistry 2019 13:12

    Content type: Research article

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  32. This work deals with the synthesis and characterization of the novel 5-((5-chloro-1H-indol-2-yl)methylene)-1,3-diethyl-2-thioxodihydro-pyrimidine-4,6(1H,5H)-dione π-bridge (D–A–D) donor–acceptor–donor compound. I...

    Authors: Mezna Saleh Altowyan, Assem Barakat, Abdullah Mohammed Al-Majid, Hazem A. Ghabbour, Abdelkader Zarrouk and Ismail Warad

    Citation: BMC Chemistry 2019 13:11

    Content type: Research article

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  33. Dyes are ranked as an important class of pollutants which affect the aesthetic property of the environment when present even in very low concentrations. This study was carried out to explore the potential use ...

    Authors: Joshua N. Edokpayi, Stanley S. Ndlovu and John O. Odiyo

    Citation: BMC Chemistry 2019 13:10

    Content type: Research article

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  34. In recent decades, incorporating polypropylene (PP) within flame retardants has proved to be an effective method of improving the thermal stabilities of PP, but too much adversely affects the mechanical proper...

    Authors: Yi-jun Liao, Xiao-li Wu, Xin Peng, Zheng Zhou, Ju-zhen Wu, Fang Wu, Tao Jiang, Jia-xuan Chen, Lin Zhu and Tao Yi

    Citation: BMC Chemistry 2019 13:9

    Content type: Research article

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  35. There are many molecules used as a drug carrier. TUD-1 is a newly synthesized mesoporous silica (SM) molecule possess two important features; consists of mesoporous so it is very suitable to be drug carrier in...

    Authors: Kamel A. Saleh, Sharah A. A. Aldulmani, Nasser S. Awwad, Hala A. Ibrahium, Tahani H. Asiri and Mohamed S. Hamdy

    Citation: BMC Chemistry 2019 13:8

    Content type: Research article

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  36. Chaenomelis Fructus is a type of traditional medicine used in China. At present, the quality standard of Chaenomelis Fructus is mainly based on the content of each component as a control index, lacking overall...

    Authors: Lili Zhu, Lexia Fang, Zongjin Li, Xiaomei Xie and Ling Zhang

    Citation: BMC Chemistry 2019 13:7

    Content type: Research article

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  37. Laser Engineered Net Shaping (LENS™) was used to produce a compositionally graded Ti-xMo (0 ≤ x ≤ 12 wt %) specimen and nine Ti-15Mo (fixed composition) specimens at different energy densities to understand th...

    Authors: Michael. Y. Mendoza, Peyman Samimi, David. A. Brice, Iman Ghamarian, Matt Rolchigo, Richard LeSar and Peter. C. Collins

    Citation: BMC Chemistry 2019 13:5

    Content type: Research article

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  38. Recent studies have suggested that aldose reductase inhibition preferentially inhibits the growth of cancer cells. However, the investigations of this issue are not many. Novel nine substituted- 4′-iminospiro[...

    Authors: Mohammed A. Khedr, Reem I. Al-Wabli, Maha S. Almutairi and Wafaa A. Zaghary

    Citation: BMC Chemistry 2019 13:3

    Content type: Research article

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  39. Glucokinase (GK) is the key enzyme expressed in β-cells of pancreas and liver hepatocytes and helps in the maintenance of blood glucose levels in normal range. Activators of GK are the novel category of drug c...

    Authors: Ajmer Singh Grewal, Rajeev Kharb, Deo Nandan Prasad, Jagdeep Singh Dua and Viney Lather

    Citation: BMC Chemistry 2019 13:2

    Content type: Research article

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  40. The resinous exudates from Escallonia illinita by products was characterized by FT-IR, NMR and HRMS. Six compounds were isolated and identified as follows: 1,5-diphenylpent-1-en-3-one (1), 4-(5-hydroxy-3,7-dimeth...

    Authors: Iván Montenegro, Elizabeth Sánchez, Enrique Werner, Patricio Godoy, Yusser Olguín, Nelson Caro, Nicole Ehrenfeld and Alejandro Madrid

    Citation: BMC Chemistry 2019 13:1

    Content type: Research article

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