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  1. Content type: Research article

    The combination between cetirizine (CET), phenylpropanolamine (PPA) and nimesulide (NMS) under trade name Nemeriv Cp tablet is prescribed for nasal congestion, cold, sneezing, and allergy. Among all published ...

    Authors: Fatma Ahmed Aly, Nahed EL-Enany, Heba Elmansi and Amany Nabil

    Citation: Chemistry Central Journal 2017 11:99

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  2. Content type: Research Article

    In this study, Ligustrum lucidum flowers as raw material, the extraction, isolation and coagulatory activity of polysaccharides were carried out for the first time. The crude polysaccharide was obtained by hot wa...

    Authors: Zhenhua Yin, Wei Zhang, Juanjuan Zhang and Wenyi Kang

    Citation: Chemistry Central Journal 2017 11:98

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  3. Content type: Research Article

    The plant biomass and agro-industrial wastes show great potential for their use as attractive low cost substrates in biotechnological processes. Wheat straw and corn cob as hemicellulosic substrates were acid ...

    Authors: Abdul Ghaffar, Muhammad Yameen, Nosheen Aslam, Fatima Jalal, Razia Noreen, Bushra Munir, Zahed Mahmood, Sadaf Saleem, Naila Rafiq, Sadia Falak, Imtiaz Mahmood Tahir, Muhammad Noman, Muhammad Umar Farooq, Samina Qasim and Farooq Latif

    Citation: Chemistry Central Journal 2017 11:97

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  4. Content type: Research article

    This study focused on maximizing the extraction yield of total phenolics and flavonoids from Curcuma Zedoaria leaves as a function of time (80–120 min), temperature (60–80 °C) and ethanol concentration (70–90 v/v...

    Authors: Nur Fauwizah Azahar, Siti Salwa Abd Gani and Nor Fadzillah Mohd Mokhtar

    Citation: Chemistry Central Journal 2017 11:96

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  5. Content type: Review

    The sunflower (Helianthus annuus L.) seed and sprout is a ubiquitous crop with abundant nutrients and biological activities. This review summarizes the nutritional and medical importance currently recognized but ...

    Authors: Shuangshuang Guo, Yan Ge and Kriskamol Na Jom

    Citation: Chemistry Central Journal 2017 11:95

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  6. Content type: Research article

    12N-benzyl matrinic acid analogues had been identified to be a novel scaffold of anti-HCV agents with a specific mechanism, and the representative compound 1 demonstrated a moderate anti-HCV activity. The intensi...

    Authors: Sheng Tang, Zong-Gen Peng, Ying-Hong Li, Xin Zhang, Tian-Yun Fan, Jian-Dong Jiang, Yan-Xiang Wang and Dan-Qing Song

    Citation: Chemistry Central Journal 2017 11:94

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  7. Content type: Research article

    Bioactive activities of adzuki bean have been widely reported, however, the phytochemical information of adzuki bean is incomplete. The aim of this study was to characterize and quantify flavonoids and saponin...

    Authors: Rui Liu, Zongwei Cai and Baojun Xu

    Citation: Chemistry Central Journal 2017 11:93

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  8. Content type: Research article

    The use of agricultural and food by-products is an economical solution to industrial biotechnology. The apricot press residues are abounding by-products from juice industry which can be used as substrates in s...

    Authors: Francisc Vasile Dulf, Dan Cristian Vodnar, Eva-Henrietta Dulf and Adela Pintea

    Citation: Chemistry Central Journal 2017 11:92

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  9. Content type: Research article

    The paper examines Co(II)–amino acid–imidazole systems (where amino acid = l-α-amino acid: alanine, asparagine, histidine) which, when in aqueous solutions, activate and reversibly take up dioxygen, while maintai...

    Authors: Marek Pająk, Magdalena Woźniczka, Andrzej Vogt and Aleksander Kufelnicki

    Citation: Chemistry Central Journal 2017 11:90

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  10. Content type: Research Article

    Heterocyclic pyrimidine nucleus, which is an essential base component of the genetic material of deoxyribonucleic acid, demonstrated various biological activities. A series of bis-pyrimidine Schiff bases were ...

    Authors: Sanjiv Kumar, Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah, Manikandan Selvaraj and Balasubramanian Narasimhan

    Citation: Chemistry Central Journal 2017 11:89

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  11. Content type: Research article

    Suzuki C–C cross-coupling of aryl halides with aryl boronic acids using new phosphene-free palladium complexes as precatalysts was investigated. A pyridine-based Pd(II)-complex was used in open air under therm...

    Authors: Ismail I. Althagafi, Mohamed R. Shaaban, Aisha Y. Al-dawood and Ahmad M. Farag

    Citation: Chemistry Central Journal 2017 11:88

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  12. Content type: Research Article

    A general procedure for the synthesis of amides via the direct condensation of carboxylic acids and amines in the presence of TiCl4 is reported. The amidation reaction was performed in pyridine at 85 °C with a wi...

    Authors: Antonella Leggio, Jessica Bagalà, Emilia Lucia Belsito, Alessandra Comandè, Marianna Greco and Angelo Liguori

    Citation: Chemistry Central Journal 2017 11:87

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  13. Content type: Research article

    Lesinurad is a novel selective uric acid salt transport protein 1 (URAT1) inhibitor which is approved in the USA for the treatment of gout. However, there are some shortcomings among the reported synthetic rou...

    Authors: Qing Meng, Tong Zhao, Dongwei Kang, Boshi Huang, Peng Zhan and Xinyong Liu

    Citation: Chemistry Central Journal 2017 11:86

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  14. Content type: Research article

    A series of six novel benzimidazole-pyrazole hybrid molecules was synthesized and characterized using elemental analysis (CHN) and spectroscopic methods (1HNMR, FT-IR). All the synthesized compounds were evaluate...

    Authors: Abida Noor, Neelum Gul Qazi, Humaira Nadeem, Arif-ullah Khan, Rehan Zafar Paracha, Fawad Ali and Adil Saeed

    Citation: Chemistry Central Journal 2017 11:85

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  15. Content type: Research article

    Suoyang originates from a psammophyte named Cynomorium songaricum Rupr and has been known as a phenolic-antioxidant-enriched traditional Chinese herbal medicine. The present study atte...

    Authors: Yulu Xie, Xican Li, Jieying Xu, Qian Jiang, Hong Xie, Jianfeng He and Dongfeng Chen

    Citation: Chemistry Central Journal 2017 11:84

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  16. Content type: Research article

    Radezolid (RAD, 12), biaryl oxazolidinone, was synthesised with small modifications according to the methods described in the literature. The pharmacological activity is observed only for (S)-enantiomer, therefor...

    Authors: Katarzyna Michalska, Elżbieta Bednarek, Ewa Gruba, Kornelia Lewandowska, Mikołaj Mizera and Judyta Cielecka-Piontek

    Citation: Chemistry Central Journal 2017 11:82

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  17. Content type: Research article

    Typically, oxazolinyl metal complexes are synthesized in two steps, where the free ligand is prepared by the condensation reaction between a functionalized nitrile and an amino alcohol in the presence of a Lew...

    Authors: Mei Luo, Jing Cheng Zhang, Wen Min Pang and King Kuok Hii

    Citation: Chemistry Central Journal 2017 11:81

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    The Erratum to this article has been published in Chemistry Central Journal 2017 11:91

  18. Content type: Research article

    In the past few years, increased resistance of microorganisms towards antimicrobial agents become a serious health problem, so there is a need for the discovery of new antimicrobial agents. On the other hand, ...

    Authors: Sanjiv Kumar, Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah and Balasubramanian Narasimhan

    Citation: Chemistry Central Journal 2017 11:80

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  19. Content type: Research article

    Tobacco smoke is a toxic gas-phase cocktail consisting of a broad range of organics, and free radical intermediates. The formation of smoke from a burning cigarette depends on a series of mechanisms, including...

    Authors: Audriy Jebet, Joshua Kibet, Lucy Ombaka and Thomas Kinyanjui

    Citation: Chemistry Central Journal 2017 11:79

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  20. Content type: Research article

    Chamomile, a well-known medicinal plant, is a rich source of bioactive compounds, among which two coumarin derivatives, umbelliferone and herniarin, are often found in its extracts. Chamomile extracts have fou...

    Authors: Maja Molnar, Nikolina Mendešević, Drago Šubarić, Ines Banjari and Stela Jokić

    Citation: Chemistry Central Journal 2017 11:78

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  21. Content type: Meeting Report

    To showcase the Networks’ success during phase two (2012–2016), and to set out the strategy for phase three (2017–2019), the Directed Assembly Network held a meeting at the Royal Society in London, United King...

    Authors: J. A. R. Rose, P. R. Raithby and C. Makatsoris

    Citation: Chemistry Central Journal 2017 11:77

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  22. Content type: Research article

    Two new symmetrical bis-thiourea, 2,2′-[{(terephthaloylbis(azanediyl)bis(carbonothioyl) bis(azanediyl)}dipropanoic acid] (1A) and 3,3′-[{(terephthaloylbis(azanediyl)bis (carbonothioyl)bis(azanediyl)} dipropano...

    Authors: Imran Fakhar, Bohari M. Yamin and Siti Aishah Hasbullah

    Citation: Chemistry Central Journal 2017 11:76

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  23. Content type: Research article

    The thiophene nucleus has been recognized as an important entity in the synthesis of heterocyclic compounds with promising pharmacological characteristics.

    Authors: Yahia Nasser Mabkhot, Nahed Ahmed Kaal, Seham Alterary, Salem S. Al-Showiman, Thoraya A. Farghaly and Mohammad S. Mubarak

    Citation: Chemistry Central Journal 2017 11:75

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  24. Content type: Research article

    Synthesis of 6-isomer of 5,8-O-dimethyl ether of shikonin (13), a promising anticancer scaffold, always remains a huge challenge. Herein a key intermediate for 13, 2-(1-hydroxyl-4-methyl-3-pentenyl)-1,4,5,8-tetra...

    Authors: Li Zhou, Xu Zhang and Wen Zhou

    Citation: Chemistry Central Journal 2017 11:74

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  25. Content type: Research article

    The crystal structure of a commercially available form of human recombinant (HR) insulin, Insugen (I), used in the treatment of diabetes has been determined to 0.92 Å resolution using low temperature, 100 K, s...

    Authors: David R. Lisgarten, Rex A. Palmer, Carina M. C. Lobley, Claire E. Naylor, Babur Z. Chowdhry, Zakieh I. Al-Kurdi, Adnan A. Badwan, Brendan J. Howlin, Nicholas C. J. Gibbons, José W. Saldanha, John N. Lisgarten and Ajit K. Basak

    Citation: Chemistry Central Journal 2017 11:73

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  26. Content type: Research article

    Tumor angiogenesis, essential for tumor growth and metastasis, is tightly regulated by VEGF/VEGFR and PDGF/PDGFR pathways, and therefore blocking those pathways is a promising therapeutic target. Compared to s...

    Authors: Ting-Hsuan Yang, Chun-I Lee, Wen-Hsin Huang and An-Rong Lee

    Citation: Chemistry Central Journal 2017 11:72

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  27. Content type: Research article

    Kinetics and a mechanistic investigation of the reaction between dimethyl acetylenedicarboxcylate (DMAD) and saccharin (NH heterocyclic compound) has been spectrally studied in methanol environment in the presen...

    Authors: Sayyed Mostafa Habibi-Khorassani, Mehdi Shahraki and Mahdieh Darijani

    Citation: Chemistry Central Journal 2017 11:71

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  28. Content type: Research article

    Multi drug-resistant and mycobacterial infections are a major public health challenge, leading to high mortality and socioeconomic burdens through worldwide. Novel therapeutics are necessary to treat the drug ...

    Authors: Mohana Rao Anguru, Ashok Kumar Taduri, Rama Devi Bhoomireddy, Malathi Jojula and Shravan Kumar Gunda

    Citation: Chemistry Central Journal 2017 11:68

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  29. Content type: Research article

    Uracil derivatives have a great attraction because they play an important role in pharmacological activities. Pyrimidodiazepines, lumazines, triazolopyrimidines and xanthines have significant wide spectrum act...

    Authors: Samar A. El-Kalyoubi, Eman A. Fayed and Ahmed S. Abdel-Razek

    Citation: Chemistry Central Journal 2017 11:66

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    The Erratum to this article has been published in Chemistry Central Journal 2017 11:69

  30. Content type: Methodology

    Experimental approaches for determining the metabolic properties of the drug candidates are usually expensive, time-consuming and labor intensive. There is a great deal of interest in developing computational ...

    Authors: Jiajia Meng, Shiliang Li, Xiaofeng Liu, Mingyue Zheng and Honglin Li

    Citation: Chemistry Central Journal 2017 11:65

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  31. Content type: Research article

    Pickled soybeans or vinegar beans have long been used as a folk remedy and also a supplemental nutritional source in Korea. In general the pickling process in vinegar improves the digestibility of soybeans as ...

    Authors: Ill-Min Chung, Jin-Young Oh and Seung-Hyun Kim

    Citation: Chemistry Central Journal 2017 11:64

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  32. Content type: Research article

    This study has demonstrated the use of crystallography, topology and graph set analysis in the description and classification of the complex hydrogen bonded network of triamterene. The aim is to give a brief o...

    Authors: David S. Hughes, Amit Delori, Abida Rehman and William Jones

    Citation: Chemistry Central Journal 2017 11:63

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  33. Content type: Research article

    A simple, rapid and accurate stability-indicating reverse phase high performance liquid chromatography (RP-HPLC) was developed and validated for the determination of brimonidine tartrate in brimonidine tartrat...

    Authors: Jianguo Sun, Xiuwen Zhang and Taomin Huang

    Citation: Chemistry Central Journal 2017 11:62

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  34. Content type: Review

    In these recent years, magnetite (Fe3O4) has witnessed a growing interest in the scientific community as a potential material in various fields of application namely in catalysis, biosensing, hyperthermia treatme...

    Authors: Essy Kouadio Fodjo, Koffi Mouroufié Gabriel, Brou Yapi Serge, Dan Li, Cong Kong and Albert Trokourey

    Citation: Chemistry Central Journal 2017 11:58

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  35. Content type: Research article

    The black turtle bean (BTB) is most widely consumed legume all over the world having anticancer activity. The aim of the study was to analyse the apoptotic effects of BTB extracts on human breast cancer cell l...

    Authors: Suresh Kumar, Vinay Kumar Sharma, Savita Yadav and Sharmistha Dey

    Citation: Chemistry Central Journal 2017 11:56

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  36. Content type: Research article

    Clinacanthus nutans Lindau is a well-known plant, native to tropical Asian countries. Reports on this plant that is rich in phenolic compounds have focused on its therapeutic anti-infl...

    Authors: Intan Soraya Che Sulaiman, Mahiran Basri, Hamid Reza Fard Masoumi, Wei Jian Chee, Siti Efliza Ashari and Maznah Ismail

    Citation: Chemistry Central Journal 2017 11:54

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  37. Content type: Research article

    Pyrazolo[1,5-a]pyrimidines are purine analogues. They have beneficial properties as antimetabolites in purine biochemical reactions. This division compounds have attracted wide pharmaceutical interest because of ...

    Authors: Nadia A. Abdelriheem, Yasser H. Zaki and Abdou O. Abdelhamid

    Citation: Chemistry Central Journal 2017 11:53

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  38. Content type: Research article

    Due to their interesting and versatile biological activity, thiophene-containing compounds have attracted the attention of both chemists and medicinal chemists. Some of these compounds have anticancer, antibac...

    Authors: Yahia N. Mabkhot, Salim S. Al-Showiman, Saied M. Soliman, Hazem A. Ghabbour, Murad A. AlDamen and Mohammad S. Mubarak

    Citation: Chemistry Central Journal 2017 11:51

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  39. Content type: Research article

    The diacylhydrazine derivatives have attracted considerable attention in recently years due to their simple structure, low toxicity, and high insecticidal selectivity. As well as 3-bromo-1-(3-chloropyridin-2-y...

    Authors: Yanyan Wang, Fangzhou Xu, Gang Yu, Jun Shi, Chuanhui Li, A’li Dai, Zhiqian Liu, Jiahong Xu, Fenghua Wang and Jian Wu

    Citation: Chemistry Central Journal 2017 11:50

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