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  2. We have synthesized new series of bisindole analogs (1–27), characterized by 1HNMR and HR-EI-MS and evaluated for their anti-leishmanial potential. All compounds showed outstanding inhibitory potential with IC50 ...

    Authors: Muhammad Taha, Imad Uddin, Mohammed Gollapalli, Noor Barak Almandil, Fazal Rahim, Rai Khalid Farooq, Muhammad Nawaz, Mohamed Ibrahim, Mohammed A. Alqahtani, Yasser A. Bamarouf and Manikandan Selvaraj

    Citation: BMC Chemistry 2019 13:102

    Content type: Research article

    Published on:

  4. Thirty-four imidazole-based compounds synthesized by one-pot catalytic method were evaluated for their antifungal and antibacterial activities against several fungal and bacterial strains. None of the compound...

    Authors: Btissam Bouchal, Farid Abrigach, Abdelilah Takfaoui, Manal Elidrissi Errahhali, Mounia Elidrissi Errahhali, Pierre H. Dixneuf, Henri Doucet, Rachid Touzani and Mohammed Bellaoui

    Citation: BMC Chemistry 2019 13:100

    Content type: Research article

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  5. Paracetamol is an analgesic-antipyretic drug and Ibuprofen is a non-steroidal anti-inflammatory drug. They are co-formulated as tablets to improve analgesia, to simplify prescribing and to improve patient comp...

    Authors: Christine M. El-Maraghy and Nesrine T. Lamie

    Citation: BMC Chemistry 2019 13:99

    Content type: Research article

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  6. Sevelamer (polyallyamine resin)-supported sulfonic acid (S-SO3H) has been prepared from the reaction of sevelamer with chlorosulfonic acid and characterized using FT-IR spectroscopy, scanning electronmicroscopy (...

    Authors: Xian-Liang Zhao, Makombe Shelton and Ke-Fang Yang

    Citation: BMC Chemistry 2019 13:98

    Content type: Research article

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  7. Cu2O supported on peanut shell (Cu2O@PS) was prepared by the reaction of copper acetate and peanut shell powder as a naturally available biopolymer support. The prepared catalyst was used as an efficient and reus...

    Authors: Zahra Dolatkhah, Abolfazl Mohammadkhani, Shahrzad Javanshir and Ayoob Bazgir

    Citation: BMC Chemistry 2019 13:97

    Content type: Research article

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  8. Heterocyclic 1,3-diazine nucleus is a valuable pharmacophore in the field of medicinal chemistry and exhibit a wide spectrum of biological activities. PharmMapper, a robust online tool used for establishing th...

    Authors: Sanjiv Kumar, Deepika Sharma, Balasubramanian Narasimhan, Kalavathy Ramasamy, Syed Adnan Ali Shah, Siong Meng Lim and Vasudevan Mani

    Citation: BMC Chemistry 2019 13:96

    Content type: Research article

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  9. Sodium benzoate (SB) is widely used as a preservative in food industry, and bovine serum albumin (BSA) is a major carrier protein similar to human serum albumin (HSA), the study of the binding between the two ...

    Authors: Jing Yu, Jian-Yi Liu, Wei-Ming Xiong, Xiao-Yue Zhang and Yue Zheng

    Citation: BMC Chemistry 2019 13:95

    Content type: Research article

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  10. Flickingeria fimbriata is commonly applied in China as a traditional Chinese medicine (TCM), however the quality control of it is incomplete. In this work, we aim to identify and quantify the structures of C-glyc...

    Authors: Yawen Wang, Zhiyun Liang, Xian Liao, Chujuan Zhou, Zhenshan Xie, Sha Zhu, Gang Wei and Yuechun Huang

    Citation: BMC Chemistry 2019 13:94

    Content type: Research article

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  11. Bidi, an indigenous form of cigarette in South Asian countries, is popular because of its low cost and multi-flavored variants. Although recent studies have shown that bidi smokers suffer from various adverse ...

    Authors: Omobola Ajoke Oladipupo, Dibyendu Dutta and Ngee Sing Chong

    Citation: BMC Chemistry 2019 13:93

    Content type: Research article

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  12. Atractylodis rhizoma, is the dried rhizomes of Atractylodes lancea (Thunb.) DC. or A. chinensis (DC.) Koidz. Both of two are pharmacologically and economically important, while with differences in efficacy. There...

    Authors: Dan Zhuang, Jing Qin, Hui-yang Wang, Yi Zhang, Chun-yao Liu, Qing-qing Ding and Guang-ping Lv

    Citation: BMC Chemistry 2019 13:92

    Content type: Research article

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  13. Sulfonamide derivatives are of great attention due to their wide spectrum of biological activities. Sulfonamides conjugated with acetamide fragments exhibit antimicrobial and anticancer activities. The inhibit...

    Authors: Essam M. Hussein, Munirah M. Al-Rooqi, Shimaa M. Abd El-Galil and Saleh A. Ahmed

    Citation: BMC Chemistry 2019 13:91

    Content type: Research article

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  14. Benzimidazole is a valuable pharmacophore in the field of medicinal chemistry and exhibit wide spectrum of biological activity. Molecular docking technique is routinely used in modern drug discovery for unders...

    Authors: Sumit Tahlan, Sanjiv Kumar, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Vasudevan Mani and Balasubramanian Narasimhan

    Citation: BMC Chemistry 2019 13:90

    Content type: Research article

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  15. Organic compounds that contain nitrogen are very important intermediates in pharmaceutical and chemical industry. Hydroamination is the reaction that can form C–N bond with high atom economy. The research progres...

    Authors: Jingpei Huo, Guozhang He, Weilan Chen, Xiaohong Hu, Qianjun Deng and Dongchu Chen

    Citation: BMC Chemistry 2019 13:89

    Content type: Review

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  17. In continuation of our work, new diazenyl chalcones scaffolds (C-18 to C-27) were efficiently synthesized from substituted acetophenone azo dyes (A–E) by base catalyzed Claisen–Schmidt condensation with different...

    Authors: Harmeet Kaur, Jasbir Singh and Balasubramanian Narasimhan

    Citation: BMC Chemistry 2019 13:87

    Content type: Research article

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  18. Pesticides and herbicides have been used extensively in agricultural practices to control pests and increase crop yields. Paraquat (PQT2+, 1,1-dimethyl-4,4-dipyridinium chloride) is one of the herbicide that belo...

    Authors: Shehdeh Jodeh, Ghadir Hanbali, Said Tighadouini, Smaail Radi, Othman Hamed and Diana Jodeh

    Citation: BMC Chemistry 2019 13:86

    Content type: Research article

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  19. Pyrimidine nucleus is a significant pharmacophore that exhibited excellent pharmacological activities. A series of pyrimidine scaffolds was synthesized and its chemical structures were confirmed by physicochem...

    Authors: Sanjiv Kumar, Archana Kaushik, Balasubramanian Narasimhan, Syed Adnan Ali Shah, Siong Meng Lim, Kalavathy Ramasamy and Vasudevan Mani

    Citation: BMC Chemistry 2019 13:85

    Content type: Research article

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  20. Lipophilicity is a physicochemical property of an essential importance in medicinal chemistry; therefore, fast and reliable measurement of lipophilicity will affect greatly the drug discovery process.

    Authors: Heba Elmansi, Jenny Jeehan Nasr, Azza H. Rageh, Mohamed I. El-Awady, Ghada S. Hassan, Hatem A. Abdel-Aziz and Fathalla Belal

    Citation: BMC Chemistry 2019 13:84

    Content type: Research article

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  21. A simple, rapid and sensitive ultrahigh performance liquid chromatographic method was developed for the determination of the anti-diabetic drug: empagliflozin (EMPA) and three related substances in spiked huma...

    Authors: Mokhtar M. Mabrouk, Suzan M. Soliman, Heba M. El-Agizy and Fotouh R. Mansour

    Citation: BMC Chemistry 2019 13:83

    Content type: Research article

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  22. Highly sensitive and selective liquid chromatography/tandem mass spectrometry (LC–MS/MS) method was developed and validated for the simultaneous estimation of the recently approved oral hypoglycemic mixture; m...

    Authors: Dalia Mohamed, Mona S. Elshahed, Tamer Nasr, Nageh Aboutaleb and Ola Zakaria

    Citation: BMC Chemistry 2019 13:82

    Content type: Research article

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  23. The dynamic changes of secondary metabolites and tyrosinase activity of Malus pumila flowers were investigated during blooming for full use of M. pumila flowers. Phlorizin, astragalin and afzelin were selected as...

    Authors: Lili Cui, Xingzi Hou, Wenjing Li, Yuchun Leng, Yang Zhang, Xinjuan Li, Yangyang Hou, Zhenhua Liu and Wenyi Kang

    Citation: BMC Chemistry 2019 13:81

    Content type: Research article

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  25. The use of natural cellulosic fibers as materials in the reinforcements of polymer composites and sorption of oil from water, has directed more focus on acetylation than other known chemical modification metho...

    Authors: Jude Chinedu Onwuka, Edith Bolanle Agbaji, Victor Olatunji Ajibola and Friday Godwin Okibe

    Citation: BMC Chemistry 2019 13:79

    Content type: Research article

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  26. Comtrex® tablets composed of paracetamol, pseudoephedrine and brompheniramine are widely used for relieving symptoms related to common cold. This study has overcome the challenging dosage form ratio (250:15:1) an...

    Authors: Souha Hosam Youssef, Dalia Mohamed, Maha Abdel Monem Hegazy and Amr Badawey

    Citation: BMC Chemistry 2019 13:78

    Content type: Research article

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  27. The various extracts of Trifolium resupinatum (Persian clover) sprout was obtained by using different solvents and microwave assisted extraction in the present study. Then, the bifunctionalized nanoliposomes were...

    Authors: S. Zahra Sayyed-Alangi and Meysam Nematzadeh

    Citation: BMC Chemistry 2019 13:77

    Content type: Research article

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  28. 5-Hydroxytryptamine (also known as 5-HT, serotonin) is one of the monoamine neurotransmitters which is distributed widely in plasma and brain of mammals and plays important roles in physiological manipulations...

    Authors: Qiangqiang He, Maoru Li, Xuechun Wang, Zhenjiang Xia, Yuzhi Du, Yan Li, Lixin Wei and Jing Shang

    Citation: BMC Chemistry 2019 13:76

    Content type: Methodology article

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  29. One of the major causes of mortality all over the world is chronic obstructive pulmonary disease (COPD). Recently approved combined inhaler of formoterol fumarate (FF) and glycopyrronium bromide (GLY) has been...

    Authors: Yomna A. Salem, Mohammed E. A. Hammouda, Mohamed A. Abu El-Enin and Saadia M. El-Ashry

    Citation: BMC Chemistry 2019 13:75

    Content type: Research article

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  30. Gracilaria lemaneiformis is a common red alga used as a raw material source for the agar industry. Its extract is rich in natural volatile constituents (VCs) having antioxidant activities. Herein, a sustainable m...

    Authors: Shengliang Yuan, Kefeng Wu, Zhihong Duan, Yanxia Huang, Yingnian Lu and Xiaoli Ma

    Citation: BMC Chemistry 2019 13:74

    Content type: Research article

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  32. Paeonia suffruticosa is an important traditional Chinese herb used to treat osteoarthritis (OA) and oligostilbenes are the main active ingredient of the seeds of P. suffruticosa. The monomer trans-resveratrol of ...

    Authors: Yu-Kun He, Xiao-tong Cen, Shuang-shuang Liu, Hua-ding Lu and Chun-nian He

    Citation: BMC Chemistry 2019 13:72

    Content type: Research article

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  34. Parabens and sorbic acid are commonly used as food preservatives due to their antimicrobial effect. However, their use in foods for infants and young children is not permitted in the European Union. Previous s...

    Authors: Theodoros Potouridis, Alena Knauz, Elisabeth Berger and Wilhelm Püttmann

    Citation: BMC Chemistry 2019 13:70

    Content type: Research article

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  35. The title compounds, 2-azaspiro[4.5]deca-1-one, C9H15NO, (1a), cis-8-methyl-2-azaspiro[4.5]deca-1-one, C10H17NO, (1b), and trans-8-methyl-2-azaspiro[4.5]deca-1-one, C10H17NO, (1c), were synthesized from benzoic a...

    Authors: Tobias Krueger, Alexandra Kelling, Torsten Linker and Uwe Schilde

    Citation: BMC Chemistry 2019 13:69

    Content type: Research article

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  36. Ru(bpy)2dppz2+ has been widely used as a probe for exploring the structure of double-stranded DNA (dsDNA). The flexibility change of DNA helix is important in many of its biological functions but not well underst...

    Authors: Fuchao Jia, Pascal Hébraud, Kezhen Han, Jing Wang, Xingguo Liang and Bo Liu

    Citation: BMC Chemistry 2019 13:68

    Content type: Research article

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  37. The Zika virus (ZIKV) has gained attention for the last few years due to the congenital microcephaly and Guillain–Barre Syndrome that resulted in humans. The non-structural protein-3 (NS3) helicase of ZIKV pla...

    Authors: Syed Lal Badshah, Nasir Ahmad, Ashfaq Ur Rehman, Khalid Khan, Asad Ullah, Abdulrhman Alsayari, Abdullatif Bin Muhsinah and Yahia N. Mabkhot

    Citation: BMC Chemistry 2019 13:67

    Content type: Research article

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  39. In search of effective antimicrobial and cytotoxic agents, a series of indole hybridized diazenyl derivatives (DS-1 to DS-21) was efficiently prepared by condensation of diazotized p-aminoacetophenone with indole...

    Authors: Harmeet Kaur, Jasbir Singh and Balasubramanian Narasimhan

    Citation: BMC Chemistry 2019 13:65

    Content type: Research article

    Published on:

  40. Nowadays, there is a growing interest in innovative and more efficient therapeutics—biopharmaceuticals, based on peptides or proteins. There are increased demands on quality control of such therapeutics. One o...

    Authors: Juraj Piestansky, Jaroslav Galba, Dominika Olesova, Branislav Kovacech and Andrej Kovac

    Citation: BMC Chemistry 2019 13:64

    Content type: Research article

    Published on:

  41. Following publication of the original article [1], the authors reported an error in Schemes 1 and 2 and repeated line in subsection “Bis(ligand) nickel(II) chelate (NiL12)”.

    Authors: Mei Luo, Jing Cheng Zhang, Hao Yin, Cheng Ming Wang, Susan Morris-Natschke and Kuo-Hsiung Lee

    Citation: BMC Chemistry 2019 13:63

    Content type: Correction

    Published on:

    The original article was published in BMC Chemistry 2019 13:51

  42. Bombyx mori silk fibroin-based materials have good biocompatibility and biodegradability. In order to maximize their utility while maintain appropriate features, silk fibroin (SF) films were modified with reduced...

    Authors: Xiaoning Zhang, Hong Bao, Carrie Donley, Jianwei Liang, Sha Yang and Shui Xu

    Citation: BMC Chemistry 2019 13:62

    Content type: Research article

    Published on:

  43. In this study, a simple one-step ionic liquid-based ultrasound-assisted dispersive liquid–liquid microextraction technique was coupled with high-performance liquid chromatography for the analysis of four pyret...

    Authors: Yiyi Liao, Yuge Hou, Yan Zhong, Hong Chen, Chang Xu, Makoto Tsunoda, Yingxia Zhang, Shiming Deng and Yanting Song

    Citation: BMC Chemistry 2019 13:61

    Content type: Research article

    Published on:

  44. In order to overcome the challenges of microbial resistance as well as to improve the effectiveness and selectivity of chemotherapeutic agents against cancer, a novel series of 4-(4-bromophenyl)-thiazol-2-amin...

    Authors: Deepika Sharma, Sanjiv Kumar, Balasubramanian Narasimhan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah and Vasudevan Mani

    Citation: BMC Chemistry 2019 13:60

    Content type: Research article

    Published on:

  45. This paper describes the application of response surface methodology (RSM) to develop a miniaturized metal organic framework based pipette-tip solid phase extraction for the extraction of malachite green (MG),...

    Authors: Sayyed Hossein Hashemi, Massoud Kaykhaii, Ahmad Jamali Keikha, Elahe Mirmoradzehi and Ghasem Sargazi

    Citation: BMC Chemistry 2019 13:59

    Content type: Research article

    Published on:

  46. Escalating energy security, burgeoning population and rising costs of fossil fuels have focussed our attention on tapping renewable energy sources. As the utilization of food crops for biofuel production culmi...

    Authors: Rintu Banerjee, Anjani Devi Chintagunta and Subhabrata Ray

    Citation: BMC Chemistry 2019 13:58

    Content type: Research article

    Published on:

  47. Thanks to its specific chemical and physical properties, graphene has aroused growing interest in many fields of Science and Technology. The present study focuses on the properties of microcrystalline chitosan...

    Authors: Marta E. Lichawska, Aleksander Kufelnicki and Magdalena Woźniczka

    Citation: BMC Chemistry 2019 13:57

    Content type: Research article

    Published on:

  48. Identification and screening of cultivars rich in bioactive phytoconstituents can be potentially useful to make nutrient-dense dishes and in medicinal formulations. In this study, we have identified, character...

    Authors: Awraris Derbie Assefa, Susanna Choi, Jae-Eun Lee, Jung-Sook Sung, On-Sook Hur, Na-Young Ro, Ho-Sun Lee, Suk-Woo Jang and Ju-Hee Rhee

    Citation: BMC Chemistry 2019 13:56

    Content type: Research article

    Published on:

  49. Many reports have also shown that the silver nanoparticles can effectively increase the anticancer drug activity and intensely enhance the drug curative effect. The adsorption of 6MP on nanomaterials has recei...

    Authors: Hongjiang Ren, Fan Chen, Xiaojun Li and Yaping He

    Citation: BMC Chemistry 2019 13:55

    Content type: Research article

    Published on:

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