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  1. Dihydrofolate reductase (DHFR) is an important target for antimetabolite class of antimicrobials because it participates in purine synthesis. 2-mercaptobenzimidazole (2MBI) has similar structural features as p...

    Authors: Sumit Tahlan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Vasudevan Mani and Balasubramanian Narasimhan

    Citation: BMC Chemistry 2019 13:12

    Content type: Research article

    Published on:

  2. This work deals with the synthesis and characterization of the novel 5-((5-chloro-1H-indol-2-yl)methylene)-1,3-diethyl-2-thioxodihydro-pyrimidine-4,6(1H,5H)-dione π-bridge (D–A–D) donor–acceptor–donor compound. I...

    Authors: Mezna Saleh Altowyan, Assem Barakat, Abdullah Mohammed Al-Majid, Hazem A. Ghabbour, Abdelkader Zarrouk and Ismail Warad

    Citation: BMC Chemistry 2019 13:11

    Content type: Research article

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  3. Dyes are ranked as an important class of pollutants which affect the aesthetic property of the environment when present even in very low concentrations. This study was carried out to explore the potential use ...

    Authors: Joshua N. Edokpayi, Stanley S. Ndlovu and John O. Odiyo

    Citation: BMC Chemistry 2019 13:10

    Content type: Research article

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  4. In recent decades, incorporating polypropylene (PP) within flame retardants has proved to be an effective method of improving the thermal stabilities of PP, but too much adversely affects the mechanical proper...

    Authors: Yi-jun Liao, Xiao-li Wu, Xin Peng, Zheng Zhou, Ju-zhen Wu, Fang Wu, Tao Jiang, Jia-xuan Chen, Lin Zhu and Tao Yi

    Citation: BMC Chemistry 2019 13:9

    Content type: Research article

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  5. There are many molecules used as a drug carrier. TUD-1 is a newly synthesized mesoporous silica (SM) molecule possess two important features; consists of mesoporous so it is very suitable to be drug carrier in...

    Authors: Kamel A. Saleh, Sharah A. A. Aldulmani, Nasser S. Awwad, Hala A. Ibrahium, Tahani H. Asiri and Mohamed S. Hamdy

    Citation: BMC Chemistry 2019 13:8

    Content type: Research article

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  6. Chaenomelis Fructus is a type of traditional medicine used in China. At present, the quality standard of Chaenomelis Fructus is mainly based on the content of each component as a control index, lacking overall...

    Authors: Lili Zhu, Lexia Fang, Zongjin Li, Xiaomei Xie and Ling Zhang

    Citation: BMC Chemistry 2019 13:7

    Content type: Research article

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  8. Laser Engineered Net Shaping (LENS™) was used to produce a compositionally graded Ti-xMo (0 ≤ x ≤ 12 wt %) specimen and nine Ti-15Mo (fixed composition) specimens at different energy densities to understand th...

    Authors: Michael. Y. Mendoza, Peyman Samimi, David. A. Brice, Iman Ghamarian, Matt Rolchigo, Richard LeSar and Peter. C. Collins

    Citation: BMC Chemistry 2019 13:5

    Content type: Research article

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  10. Recent studies have suggested that aldose reductase inhibition preferentially inhibits the growth of cancer cells. However, the investigations of this issue are not many. Novel nine substituted- 4′-iminospiro[...

    Authors: Mohammed A. Khedr, Reem I. Al-Wabli, Maha S. Almutairi and Wafaa A. Zaghary

    Citation: BMC Chemistry 2019 13:3

    Content type: Research article

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  11. Glucokinase (GK) is the key enzyme expressed in β-cells of pancreas and liver hepatocytes and helps in the maintenance of blood glucose levels in normal range. Activators of GK are the novel category of drug c...

    Authors: Ajmer Singh Grewal, Rajeev Kharb, Deo Nandan Prasad, Jagdeep Singh Dua and Viney Lather

    Citation: BMC Chemistry 2019 13:2

    Content type: Research article

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  12. The resinous exudates from Escallonia illinita by products was characterized by FT-IR, NMR and HRMS. Six compounds were isolated and identified as follows: 1,5-diphenylpent-1-en-3-one (1), 4-(5-hydroxy-3,7-dimeth...

    Authors: Iván Montenegro, Elizabeth Sánchez, Enrique Werner, Patricio Godoy, Yusser Olguín, Nelson Caro, Nicole Ehrenfeld and Alejandro Madrid

    Citation: BMC Chemistry 2019 13:1

    Content type: Research article

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  14. Although the development of antibiotic and antioxidant manufacturing, the problem of bacterial resistance and food and/or cosmetics oxidation still needs more efforts to design new derivatives which can help t...

    Authors: Hiba Ali Hasan, Emilia Abdulmalek, Mohd Basyaruddin Abdul Rahman, Khozirah Binti Shaari, Bohari Mohd. Yamin and Kim Wei Chan

    Citation: Chemistry Central Journal 2018 12:145

    Content type: Research Article

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  15. Etravirine (ETV) was approved as the second generation drug for use in individuals infected with HIV-1 in 2008 by the U.S. FDA with its unique antiviral activity, high specificity, and low toxicity. However, t...

    Authors: Da Feng, Fenju Wei, Zhao Wang, Dongwei Kang, Peng Zhan and Xinyong Liu

    Citation: Chemistry Central Journal 2018 12:144

    Content type: Research Article

    Published on:

  16. Ligand exchange method is introduced as an alternative to Job’s and mole ratio methods for studying the stoichiometry of relatively weak metal complexes in solutions. The method involves adding varying amounts...

    Authors: Mokhtar Mabrouk, Sherin F. Hammad, Mohamed A. Abdelaziz and Fotouh R. Mansour

    Citation: Chemistry Central Journal 2018 12:143

    Content type: Research Article

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  17. Differences in health risks between different styles of smokeless tobacco products (STPs) have prompted interest in their relative levels of toxic chemicals. We report here the development of methods for the a...

    Authors: Kevin McAdam, Trevor Enos, Carol Goss, Harriet Kimpton, Arif Faizi, Steve Edwards, Christopher Wright, Andrew Porter and Brad Rodu

    Citation: Chemistry Central Journal 2018 12:142

    Content type: Research Article

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  18. An alarming requirement for finding newer antidiabetic glitazones as agonists to PPARγ are on its utmost need from past few years as the side effects associated with the available drug therapy is dreadful. In ...

    Authors: Subhankar P. Mandal, Aakriti Garg, P. Prabitha, Ashish D. Wadhwani, Laxmi Adhikary and B. R. Prashantha Kumar

    Citation: Chemistry Central Journal 2018 12:141

    Content type: Research Article

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  19. Pineapple is highly relished for its attractive sweet flavour and it is widely consumed in both fresh and canned forms. Pineapple flavour is a blend of a number of volatile and non-volatile compounds that are ...

    Authors: Ola Lasekan and Fatma Khalifa Hussein

    Citation: Chemistry Central Journal 2018 12:140

    Content type: Research Article

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  20. The emergence of bacterial resistance is a major public health problem. It is essential to develop and synthesize new therapeutic agents with better activity. The mode of actions of certain newly developed ant...

    Authors: Sumit Tahlan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Vasudevan Mani and Balasubramanian Narasimhan

    Citation: Chemistry Central Journal 2018 12:139

    Content type: Research Article

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  21. Tuberculosis is an air-borne disease, mostly affecting young adults in their productive years. Here, Ligand-based drug design approach yielded a series of 23 novel 6-(4-nitrophenoxy)-1H-imidazo[4,5-b]pyridine der...

    Authors: Jineetkumar Gawad and Chandrakant Bonde

    Citation: Chemistry Central Journal 2018 12:138

    Content type: Research Article

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  22. Thiophene and its substituted derivatives are very important class of heterocyclic compounds which shows interesting applications in the field of medicinal chemistry. It has made an indispensable anchor for me...

    Authors: Rashmi Shah and Prabhakar Kumar Verma

    Citation: Chemistry Central Journal 2018 12:137

    Content type: Review

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  23. A facile and efficient palladium-catalyzed borylation of aryl (pseudo)halides at room temperature has been developed. Arylboronic esters were expeditiously assembled in good yields and with a broad substrate s...

    Authors: Hong Ji, Jianghong Cai, Nana Gan, Zhaohua Wang, Liyang Wu, Guorong Li and Tao Yi

    Citation: Chemistry Central Journal 2018 12:136

    Content type: Research Article

    Published on:

  24. This research work was executed to determine chemical composition, anti-oxidant and anti-microbial potential of the essential oils extracted from the leaves and stem of Daphne mucronata Royle. From leaves and ste...

    Authors: Iqra Ashraf, Muhammad Zubair, Komal Rizwan, Nasir Rasool, Muhammad Jamil, Shakeel Ahmad Khan, Rasool Bakhsh Tareen, Viqar Uddin Ahmad, Abid Mahmood, Muhammad Riaz, M. Zia-Ul-Haq and Hawa ZE Jaafar

    Citation: Chemistry Central Journal 2018 12:135

    Content type: Research Article

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  25. In this study dibenzylidene ketone derivatives (2E,5E)-2-(4-methoxybenzylidene)-5-(4-nitrobenzylidene) cyclopentanone (AK-1a) and (1E,4E)-4-(4-nitrobenzylidene)-1-(4-nitrophenyl) oct-1-en-3-one (AK-2a) were newly...

    Authors: Tauqeer Ahmed, Arif-ullah Khan, Muzaffar Abbass, Edson Rodrigues Filho, Zia Ud Din and Aslam Khan

    Citation: Chemistry Central Journal 2018 12:134

    Content type: Research Article

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  26. In this study, sago starch was modified in order to enhance its physicochemical properties. Carboxymethylation was used to introduce a carboxymethyl group into a starch compound. The carboxymethyl sago starch ...

    Authors: Nur Fattima’ Al-Zahara’ Tuan Mohamood, Norhazlin Zainuddin, Mansor Ahmad@Ayob and Sheau Wei Tan

    Citation: Chemistry Central Journal 2018 12:133

    Content type: Research Article

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  27. In spite of the development of new measurement techniques in recent years, the rapid and accurate speciation of thallium in environmental aqueous samples remains a challenge. In this context, a novel method of...

    Authors: Qingxiang Xiao, Atta Rasool, Tangfu Xiao and Philippe C. Baveye

    Citation: Chemistry Central Journal 2018 12:132

    Content type: Methodology article

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  28. Banana as a typical climacteric fruit soften rapidly, resulting in a very short shelf life after harvest. Sodium dichloroisocyanurate (NaDCC) is reported to be an effectively antibacterial compound. Here, we i...

    Authors: Qixian Wu, Taotao Li, Xi Chen, Lingrong Wen, Ze Yun and Yueming Jiang

    Citation: Chemistry Central Journal 2018 12:131

    Content type: Research Article

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  29. In view of wide range of biological activities of oxazole, a new series of oxazole analogues was synthesized and its chemical structures were confirmed by spectral data (Proton/Carbon-NMR, IR, MS etc.). The sy...

    Authors: Saloni Kakkar, Sanjiv Kumar, Siong Meng Lim, Kalavathy Ramasamy, Vasudevan Mani, Syed Adnan Ali Shah and Balasubramanian Narasimhan

    Citation: Chemistry Central Journal 2018 12:130

    Content type: Research Article

    Published on:

  31. Coumarins are the phytochemicals, which belong to the family of benzopyrone, that display interesting pharmacological properties. Several natural, synthetic and semisynthetic coumarin derivatives have been dis...

    Authors: Samina Khan Yusufzai, Mohammad Shaheen Khan, Othman Sulaiman, Hasnah Osman and Dalily Nabilah Lamjin

    Citation: Chemistry Central Journal 2018 12:128

    Content type: Review

    Published on:

  32. Using a mass-loss method, we investigated the solubility change of gallium nitride (GaN) in supercritical ammonia with mixed mineralizers [ammonium chloride (NH4Cl) + ammonium bromide (NH4Br) and NH4Cl + ammonium...

    Authors: Daisuke Tomida, Kiyoshi Kuroda, Kentaro Nakamura, Kun Qiao and Chiaki Yokoyama

    Citation: Chemistry Central Journal 2018 12:127

    Content type: Research Article

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  33. The flowers of Malus pumila Mill (Rosaceae) is rich in resources, but lack of medicinal value research. Chemical constituents of the same family M. pumila have coagulatory activity. Considering the coagulatory ac...

    Authors: Zhenhua Yin, Yong Zhang, Juanjuan Zhang, Jinmei Wang and Wenyi Kang

    Citation: Chemistry Central Journal 2018 12:126

    Content type: Research Article

    Published on:

  34. A series of benzimidazole derivatives was developed and its chemical scaffolds were authenticated by NMR, IR, elemental analyses and physicochemical properties. The synthesized compounds were screened for thei...

    Authors: Neelam Vashist, Surinder Singh Sambi, Balasubramanian Narasimhan, Sanjiv Kumar, Siong Meng Lim, Syed Adnan Ali Shah, Kalavathy Ramasamy and Vasudevan Mani

    Citation: Chemistry Central Journal 2018 12:125

    Content type: Research Article

    Published on:

  35. Most chemical reactions produce unwanted by-products. In an effort to reduce environmental problems these by-products could be used to produce valuable organic chemicals. In biodiesel industry a huge amount of...

    Authors: Eva-H. Dulf, Dan Cristian Vodnar and Francisc-V. Dulf

    Citation: Chemistry Central Journal 2018 12:124

    Content type: Research Article

    Published on:

  36. A novel series of 1,2,3-triazole derivatives containing 1,4-benzothiazin-3-one ring (7a–9a, 7b–9b), (10a–12a, 10b–12b) and (13–15) were synthesized by 1,3-dipolar cycloaddition reactions of azides α-d-galactopyra...

    Authors: Mohamed Ellouz, Nada Kheira Sebbar, Ismail Fichtali, Younes Ouzidan, Zakaria Mennane, Reda Charof, Joel T. Mague, Martine Urrutigoïty and El Mokhtar Essassi

    Citation: Chemistry Central Journal 2018 12:123

    Content type: Research Article

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  37. Nowadays, is emerging a new generation of highly promising inhibitors bearing the β-ketoenol functionality. The present work relates to the first synthesis, the structure determination, the DFT studies and the...

    Authors: Said Tighadouini, Redouane Benabbes, Monique Tillard, Driss Eddike, Khadija Haboubi, Khalid Karrouchi and Smaail Radi

    Citation: Chemistry Central Journal 2018 12:122

    Content type: Research Article

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  38. This study aims to synthesise and characterise novel compounds containing 2-amino-1,3,4-thiadiazole and their acyl derivatives and to investigate antifungal activities. Similarity search, molecular dynamics an...

    Authors: Mustafa Er, Abdulati Miftah Abounakhla, Hakan Tahtaci, Ali Hasin Bawah, Süleyman Selim Çınaroğlu, Abdurrahman Onaran and Abdulilah Ece

    Citation: Chemistry Central Journal 2018 12:121

    Content type: Research Article

    Published on:

  40. Ample attention has been devoted to the construction of anti-cancer drug delivery systems with increased stability, and controlled and targeted delivery, minimizing toxic effects. In this study we have designe...

    Authors: Danushika C. Manatunga, Rohini M. de Silva, K. M. Nalin de Silva, Dulharie T. Wijeratne, Gathsaurie Neelika Malavige and Gareth Williams

    Citation: Chemistry Central Journal 2018 12:119

    Content type: Research Article

    Published on:

  41. Pyridinium Schiff bases and ionic liquids have attracted increasing interest in medicinal chemistry.

    Authors: Fawzia Faleh Al-Blewi, Nadjet Rezki, Salsabeel Abdullah Al-Sodies, Sanaa K. Bardaweel, Dima A. Sabbah, Mouslim Messali and Mohamed Reda Aouad

    Citation: Chemistry Central Journal 2018 12:118

    Content type: Research Article

    Published on:

  42. The transition metal complexes formed from Schiff base is regarded as leading molecules in medicinal chemistry. Because of the preparative availability and diversity in the structure of central group, the tran...

    Authors: Shubham Kashyap, Sanjiv Kumar, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Hari Om and Balasubramanian Narasimhan

    Citation: Chemistry Central Journal 2018 12:117

    Content type: Research Article

    Published on:

  43. The purpose of this study was to investigate the feasibility of simultaneous optimization and removal of dyes, Malachite green (MG), Rhodamine B (RhB) and Cresol Red (CR) from aqueous solutions by using Sistan...

    Authors: Sahar Marghzari, Mojtaba Sasani, Massoud Kaykhaii, Mona Sargazi and Mohammad Hashemi

    Citation: Chemistry Central Journal 2018 12:116

    Content type: Research Article

    Published on:

  44. Tubulysins family is a kind of natural compound with potent, antitumor activity. To simplify the synthesis route and find new antitumor compounds is becoming a hotspot of research recent years.

    Authors: Mingsha Shao, Xinfa Bai, Xuan Ma, Ning Yan and Lei Yao

    Citation: Chemistry Central Journal 2018 12:115

    Content type: Research Article

    Published on:

  45. Design and synthesis of new inhibitor agents to deal with pathogenic microorganisms is expanding. In this project, an efficient, environmentally friendly, economical, rapid and mild procedure was developed for...

    Authors: Hamid Beyzaei, Mahboubeh Kamali Deljoo, Reza Aryan, Behzad Ghasemi, Mohammad Mehdi Zahedi and Mohammadreza Moghaddam-Manesh

    Citation: Chemistry Central Journal 2018 12:114

    Content type: Research Article

    Published on:

  46. The oil and extracts of Lippia thymoides have been used for various medicinal and food applications. Entrepreneurs in the Amazon have been considering the economic exploitation of this plant. The present study ev...

    Authors: Sebastião G. Silva, Pablo Luis B. Figueiredo, Lidiane D. Nascimento, Wanessa A. da Costa, José Guilherme S. Maia and Eloisa Helena A. Andrade

    Citation: Chemistry Central Journal 2018 12:113

    Content type: Research Article

    Published on:

  47. Monoamine oxidase has been implicated in numerous neurological disorders. Although synthetic monoamine oxidase inhibitors (MAOI) have emerged with many side effects, the aspiration of natural based MAOI has gr...

    Authors: Priyanka Dhiman, Neelam Malik and Anurag Khatkar

    Citation: Chemistry Central Journal 2018 12:112

    Content type: Research Article

    Published on:

  48. We prepared 16 novel hydroxybenzoic acid ester conjugates of phenazine-1-carboxylic acid (PCA) and investigated their biological activity. Most of the synthesized conjugates displayed some level of fungicidal ...

    Authors: Xiang Zhu, Linhua Yu, Min Zhang, Zhihong Xu, Zongli Yao, Qinglai Wu, Xiaoying Du and Junkai Li

    Citation: Chemistry Central Journal 2018 12:111

    Content type: Research Article

    Published on:

  49. Nitrogen heterocyclic rings and sulfonamides have attracted attention of several researchers.

    Authors: Fawzia Faleh Al-blewi, Meshal A. Almehmadi, Mohamed Reda Aouad, Sanaa K. Bardaweel, Pramod K. Sahu, Mouslim Messali, Nadjet Rezki and El Sayed H. El Ashry

    Citation: Chemistry Central Journal 2018 12:110

    Content type: Research Article

    Published on:

  50. Dendrobium officinale stem is rich in polysaccharides, which play a great role in the medicinal effects of this plant. However, little was known about the polysaccharides from Dendrobium officinale leaves. Two ki...

    Authors: Min Zhang, Junwen Wu, Juanjuan Han, Hongmei Shu and Kehai Liu

    Citation: Chemistry Central Journal 2018 12:109

    Content type: Research Article

    Published on:

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  • ISSN: 2661-801X (electronic)

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BMC Chemistry

ISSN: 2661-801X

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