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  1. Type III beta phosphatidylinositol 4-kinase (PI4KIIIβ) is the only clinically validated drug target in Plasmodium kinases and therefore a critical target in developing novel drugs for malaria. Current PI4KIIIβ in...

    Authors: Akachukwu Ibezim, Mbanefo S. Madukaife, Sochi C. Osigwe, Nadja Engel, Ramanathan Karuppasamy and Fidele Ntie-Kang
    Citation: BMC Chemistry 2022 16:19
  2. The ethyl 2-[2-(2-nitrobenzylidene)hydrazinyl]thiazole-4-carboxylate (1), a thiazole ester, was synthesized by refluxing 1-(2-nitrobenzylidene)thiosemicarbazide and ethyl bromopyruvate. The compound is characteri...

    Authors: Muhammad Haroon, Tashfeen Akhtar, Muhammad Yousuf, Muhammad Nawaz Tahir, Lubna Rasheed, Syeda Saniya Zahra, Ihsan ul Haq and Muhammad Ashfaq
    Citation: BMC Chemistry 2022 16:18
  3. Human and veterinary antibiotics are typically discharged as parent chemicals in urine or feces and are known to be released into the environment via wastewater treatment plants (WWTPs). Several research inves...

    Authors: Shehdeh Jodeh, Ahlam Jaber, Ghadir Hanbali, Younes Massad, Zaki S. Safi, Smaail Radi, Valbonë Mehmeti, Avni Berisha, Said Tighadouini and Omar Dagdag
    Citation: BMC Chemistry 2022 16:17
  4. An accurate, precise, sensitive, and simple spectroscopic method was developed and validated for simultaneous quantification analysis of tretinoin (TRT) and nicotinamide (NCT) with a ratio of 1:40 (TRT: NCT) i...

    Authors: Nazira Sarkis and Abdulkader Sawan
    Citation: BMC Chemistry 2022 16:15
  5. In this research, a molecularly imprinted polymer (MIP) was synthesized and employed as a sorbent for pipette-tip micro solid phase extraction of profenofos insecticide in seawater, rice, and fish samples. The...

    Authors: Mahsa Tamandani, Sayyed Hossein Hashemi, Massoud Kaykhaii, Ahmad Jamali Keikha and Ali Nasiriyan
    Citation: BMC Chemistry 2022 16:12
  6. Excess agrochemicals input from agricultural activities and industrial effluent around Lake Ziway catchment can pose a serious threat on the lake ecosystem. Lake Ziway is a shallow freshwater lake found in the...

    Authors: Dessie Tibebe, Feleke Zewge, Brook Lemma and Yezbie Kassa
    Citation: BMC Chemistry 2022 16:11
  7. The ultrasonic assisted reverse micelle method (UARM) was used to synthesize Cu-MOF from Cu(NO3)2·3H2O and 2,6-pyridine dicarboxylic acid in a 1:1 molar proportion. It has been characterized using FT-IR, XRD, nit...

    Authors: Reza Akhavan-Sigari, Malihe Zeraati, Mohammadreza Moghaddam-Manesh, Parya Kazemzadeh, Sara Hosseinzadegan, Narendra Pal Singh Chauhan and Ghasem Sargazi
    Citation: BMC Chemistry 2022 16:10
  8. A new, green and environmentally friendly protocol has been developed for the synthesis of tetrahydrodipyrazolopyridine derivatives. The structures of these products were determined in terms of melting point, ...

    Authors: Mina Keihanfar and Bi Bi Fatemeh Mirjalili
    Citation: BMC Chemistry 2022 16:9
  9. A new diazo derivative of a pyrrolidine-2,5-dione (8) fused at position-3,4 to a dibenzobarrelene backbone has been prepared by coupling the previously reported N-arylsuccinimid (5) precursor with aryldiazonium i...

    Authors: Emmanuel Sopbué Fondjo, Abdou Salamou Njoya, Jean-de-Dieu Tamokou, Giscard Doungmo, Bruno Ndjakou Lenta, Peter F. W. Simon, Apollinaire Tsopmo and Jules-Roger Kuiate
    Citation: BMC Chemistry 2022 16:8
  10. The loss of cholinergic neurotransmission in Alzheimer's disease (AD) patients' brain is accompanied by a reduced concentration of Acetylcholine (ACh) within synaptic clefts. Thus, the use of acetylcholinester...

    Authors: Maryam Taheri, Samira Aslani, Hossein Ghafouri, Asadollah Mohammadi, Vaha Akbary Moghaddam, Nastarn Moradi and Hananeh Naeimi
    Citation: BMC Chemistry 2022 16:7
  11. Antibiotics are routinely used on poultry for therapy and prevention of diseases and to enhance animal growth. The objective of this study was to develop and validate a sensitive and reliable liquid chromatogr...

    Authors: Aynalem Lakew, Teshome Assefa, Meseret Woldeyohannes, Negussie Megersa and Bhagwan Singh Chandravanshi
    Citation: BMC Chemistry 2022 16:5
  12. The reaction process of gaseous 1,3-butadiene following ultraviolet irradiation at the temperature range from 298 to 323 K under nitrogen atmosphere was monitored by UV–vis spectrophotometry. A gaseous mini-re...

    Authors: Min Liang, Chang Yu, Suyi Dai, Haijun Cheng, Weiguang Li, Fang Lai, Li Ma and Xiongmin Liu
    Citation: BMC Chemistry 2022 16:4
  13. The subcontinent is famous for its variety of seasonal foods cooked in vegetable seed cooking oils at elevated heating. Oils are often of poor quality that effect to consumer health. The work, therefore, plann...

    Authors: Ayesha Baig, Muhammad Zubair, Sajjad Hussain Sumrra, Muhammad Faizan Nazar, Muhammad Nadeem Zafar, Kausar Jabeen, Muhammad Bilal Hassan and Umer Rashid
    Citation: BMC Chemistry 2022 16:3
  14. Paracetamol compound remains the most used pharmaceutical as an analgesic and antipyretic for pain and fever, often identified in aquatic environments. The elimination of this compound from wastewater is one o...

    Authors: Sanae Tarhouchi, Rkia Louafy, El Houssine El Atmani and Miloudi Hlaïbi
    Citation: BMC Chemistry 2022 16:2
  15. Quinolines have demonstrated various biological activities such as antimalarial, antibacterial and anticancer. Hence, compounds with such scaffold have been used as lead in drug development. This project is, t...

    Authors: Mona Fekadu, Digafie Zeleke, Bayan Abdi, Anuradha Guttula, Rajalakshmanan Eswaramoorthy and Yadessa Melaku
    Citation: BMC Chemistry 2022 16:1
  16. Thiazole-based Schiff base compounds display significant pharmacological potential with an ability to modulate the activity of many enzymes involved in metabolism. They also demonstrated to have antibacterial,...

    Authors: Fitsum Lemilemu, Mamaru Bitew, Taye B. Demissie, Rajalakshmanan Eswaramoorthy and Milkyas Endale
    Citation: BMC Chemistry 2021 15:67
  17. Liver cancer is predicted to be the sixth most diagnosed cancer globally and fourth leading cause of cancer deaths. In this study, a series of indole-3-isoxazole-5-carboxamide derivatives were designed, synthe...

    Authors: Mohammed Hawash, Deniz Cansen Kahraman, Sezen Guntekin Ergun, Rengul Cetin-Atalay and Sultan Nacak Baytas
    Citation: BMC Chemistry 2021 15:66
  18. A large volume of dye molecules finds its way into the environment, accumulates in water bodies, and makes the aquatic system unsafe to human health. Due to the complex nature of these dye materials, most of t...

    Authors: Violet M. Nkwe, Damian C. Onwudiwe and Mayowa A. Azeez
    Citation: BMC Chemistry 2021 15:65
  19. Diabetes mellitus is a systemic disease mainly caused by the disorder of metabolism, which has become huge threat to human health. Polysaccharides are the main active substance from Inonotus obliquus (I. obliquus...

    Authors: Tanye Xu, Guodao Li, Xiaobo Wang, Chongning Lv and Yuanyong Tian
    Citation: BMC Chemistry 2021 15:64
  20. A multi-class and multi-residue/contaminant method for the determination of veterinary drug and pesticide residues and mycotoxins in bovine meat has been developed and validated. The veterinary drug residues/c...

    Authors: Zehra Hajrulai-Musliu, Risto Uzunov, Stefan Jovanov, Dean Jankuloski, Velimir Stojkovski, Lazo Pendovski and James Jacob Sasanya
    Citation: BMC Chemistry 2021 15:62
  21. A chromium-based metal organic framework was synthesized and employed as an efficient sorbent for pipette tip micro-solid phase extraction and preconcentration of parabens from wastewater and shampoo samples u...

    Authors: Massoud Kaykhaii, Sayyed Hossein Hashemi, Fariba Andarz, Amin Piri and Ghasem Sargazi
    Citation: BMC Chemistry 2021 15:60

    The Correction to this article has been published in BMC Chemistry 2021 15:63

  22. Two series of benzimidazole based thio-oxadiazole and thio-thiadiazole analogues were designed and synthesised as novel antimicrobial drugs through inhibition of phenylalanyl-tRNA synthetase (PheRS), which is ...

    Authors: Nada A. Noureldin, Jennifer Richards, Hend Kothayer, Mohammed M. Baraka, Sobhy M. Eladl, Mandy Wootton and Claire Simons
    Citation: BMC Chemistry 2021 15:58
  23. In order to stabilize the whole wheat flour and extend its shelf life, microwave was employed to heat the wheat bran to inactivate the lipase in this paper. The effects of microwave heating of wheat bran on th...

    Authors: Chenling Qu, Qiankui Yang, Lina Ding, Xueke Wang, Shengqiang Liu and Min Wei
    Citation: BMC Chemistry 2021 15:57
  24. Solid-phase microextraction (SPME) is a versatile sampling and sample preparation technology that possess a significant application in the extraction and pre-concentration of a broad range of micro-pollutants ...

    Authors: Yalda Pasandideh and Habib Razmi
    Citation: BMC Chemistry 2021 15:56
  25. Juniperus Phoenicea (JP) and Calicotome Villosa (CV) are used by Jordanian populations as herbal remedies in traditional medicine. Herein, the phytochemical contents of their methanolic extracts were analyzed and...

    Authors: Ahmed Al-Mustafa, Mohammad Al-Tawarah, Mohammed Sharif Al-Sheraideh and Fatema Attia Al-Zahrany
    Citation: BMC Chemistry 2021 15:55
  26. A series of symmetrical azine derivatives containing different substituted benzyl moieties were designed, synthesized, and evaluated for their inhibitory activity against tyrosinase. The results showed that co...

    Authors: Somaye Karimian, Fatemeh Kazemi, Mahshid Attarroshan, Maryam Gholampour, Shiva Hemmati, Amirhossein Sakhteman, Yasaman Behzadipour, Maryam Kabiri, Aida Iraji and Mehdi Khoshneviszadeh
    Citation: BMC Chemistry 2021 15:54
  27. Carbon dots (C-dots) are photoluminescent nanoparticles with less than 10 nm in size. Today, many studies are performed to exploit the photoluminescence (PL) property of carbon dots, and our focus in this stud...

    Authors: Parisa Mohammad-Jafarieh, Abolfazl Akbarzadeh, Rahman Salamat-Ahangari, Mohammad Pourhassan-Moghaddam and Kazem Jamshidi-Ghaleh
    Citation: BMC Chemistry 2021 15:53
  28. Water solubility is perhaps the single most important physical–chemical property determining the environmental fate and effects of organic compounds. Its determination is particularly challenging for compounds...

    Authors: Daniel J. Letinski, Aaron D. Redman, Heidi Birch and Philipp Mayer
    Citation: BMC Chemistry 2021 15:52
  29. Local sequence context is known to have an impact on the mutational pattern seen in cancer. The RAS genes and a smoking carcinogen, Benzo[a]pyrene diol epoxide (BPDE), have been utilised to explore these context ...

    Authors: Georgina E. Menzies, Ian A. Prior, Andrea Brancale, Simon H. Reed and Paul D. Lewis
    Citation: BMC Chemistry 2021 15:51
  30. Iron phosphate, Fe2 (HPO4)3*4H2O, is synthesized at ambient temperature, using the inorganic sol–gel method coupled to the microwave route. The experimental conditions for the gelling of Fe (III)-H3PO4 system are...

    Authors: Fz. Maarouf, S. Saoiabi, K. Azzaoui, C. Chrika, H. Khalil, S. Elkaouni, S. Lhimr, O. Boubker, B. Hammouti and S. Jodeh
    Citation: BMC Chemistry 2021 15:48
  31. Thiamine (vitamin B1) is an essential micronutrient in the human diet, found both naturally and as a fortification ingredient in many foods and supplements. However, it is susceptible to degradation due to heat, ...

    Authors: Adrienne L. Voelker, Lynne S. Taylor and Lisa J. Mauer
    Citation: BMC Chemistry 2021 15:47
  32. Edible insects constitute a potential source of alternative proteins as a food supplement. The present study aimed to investigate the chemical composition, energy and nutritional values, the digestibility and ...

    Authors: Aminata Séré, Adjima Bougma, Bazoin Sylvain Raoul Bazié, Esther Traoré, Charles Parkouda, Olivier Gnankiné and Imael Henri Nestor Bassolé
    Citation: BMC Chemistry 2021 15:46
  33. Presently available chemical based synthetic preservative have emerged with various side effects, so the aspiration of natural and side effect free novel preservative has been greatly increased. As the natural...

    Authors: Amit Lather, Sunil Sharma and Anurag Khatkar
    Citation: BMC Chemistry 2021 15:45
  34. Zanthoxylum nitidium (Roxb.) DC (Rutaceae) is well known for inhibiting the proliferation of human gastric, liver, kidney and lung cancer cells, though research on its potential use in treating leukaemia is relat...

    Authors: Ying Deng, Tongtong Ding, Lulu Deng, Xiaojiang Hao and Shuzhen Mu
    Citation: BMC Chemistry 2021 15:44
  35. The present study evaluated the compost quality from municipal solid waste (MSW) and organic additives of coffee by-products and leaf of Millettia ferruginea. Compost sample (n = 30) was taken from fresh compost ...

    Authors: Masresha Mamo, Henok Kassa, Lalit Ingale and Stefaan Dondeyne
    Citation: BMC Chemistry 2021 15:43
  36. Silver orthophosphate (Ag3PO4) has received enormous attention over the past few years for its higher visible light photocatalytic performance as well as for various organic pollutants degradation in aqueous medi...

    Authors: Karim Dânoun, Rida Tabit, Abdelaziz Laghzizil and Mohamed Zahouily
    Citation: BMC Chemistry 2021 15:42
  37. Discovering and screening for potential anti-obesity, anti-diabetic, anticancer, and antioxidant treatments from natural products still in recent times the main goal for many pharmaceutical scientists. The pre...

    Authors: Nidal Jaradat, Hanaa Dacca, Mohammed Hawash and Murad N. Abualhasan
    Citation: BMC Chemistry 2021 15:41
  38. Currently, available therapies for diabetes could not achieve normal sugar values in a high percentage of treated patients. In this research project, a series of 17 benzodioxole derivatives were evaluated as a...

    Authors: Mohammed Hawash, Nidal Jaradat, Suhaib Shekfeh, Murad Abualhasan, Ahmad M. Eid and Linda Issa
    Citation: BMC Chemistry 2021 15:40
  39. Loop diuretics are commonly used in clinical practice to manage high fluid loads and to control fluid balance. In this paper, a novel quantitative analysis method for multiple components with a single marker (...

    Authors: Fuchao Chen, Baoxia Fang, Peng Li and Sicen Wang
    Citation: BMC Chemistry 2021 15:39
  40. Pyrazoles have attracted particular attention due to the diverse biological activities associated with this heterocyclic system, and some have been shown to be cytotoxic to several human cell lines. Several dr...

    Authors: José Eduardo Cadena-Cruz, Luis M. Guamán-Ortiz, Juan Carlos Romero-Benavides, Natalia Bailon-Moscoso, Kevin E. Murillo-Sotomayor, Nadia V. Ortiz-Guamán and Jorge Heredia-Moya
    Citation: BMC Chemistry 2021 15:38
  41. This mini-review assesses supercritical carbon dioxide (scCO2) extraction and high-pressure carbon dioxide pre-treatment technologies for valorisation of corn stover agricultural residues with particular focus on...

    Authors: Pakin Noppawan, Adrienne Gallant Lanctôt, Maria Magro, Pablo Gil Navarro, Nontipa Supanchaiyamat, Thomas M. Attard and Andrew J. Hunt
    Citation: BMC Chemistry 2021 15:37

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