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  1. Computer-Aided Drug Design tools are now an indispensable part of drug discovery that have made key contributions to the development of drugs. In this editorial, I briefly provide an overview of CADD emphasizi...

    Authors: Abdulilah Ece
    Citation: BMC Chemistry 2023 17:26
  2. Carbon quantum dots (CQDs) are new class of carbon nanoparticles. Recently, they have been widely used as fluorescent probes due to their easy accessibility, optical properties and chemical inertness. Many ava...

    Authors: Mona H. Abo Zaid, Nahed El-Enany, Aziza E. Mostafa, Ghada M. Hadad and Fathalla Belal
    Citation: BMC Chemistry 2023 17:25
  3. A sequential spectrophotometric resolution technique (SSRT) was developed in this study without the use of systematic separation procedures to determine drug of a quaternary combination; caffeine (CAF), pseudo...

    Authors: Khadiga M. Kelani, Mohamed S. Emara, Ahmed W. Madkour, Hany A. Batakoushy and Rehab M. Tony
    Citation: BMC Chemistry 2023 17:24
  4. The SARS-CoV-2 virus sets up a global catastrophe, and countries all around the world made significant efforts to halt the spread. Nirmatrelvir (NMV) was lately approved by the FDA as a safe and well-tolerated...

    Authors: Sara I. Aboras and Hadir M. Maher
    Citation: BMC Chemistry 2023 17:23
  5. Enantioseparation of five β-adrenergic blockers was studied using two mobile phases on a cellulose tris(3‐chloro‐4‐methylphenylcarbamate) (Lux-Cellulose-2) chiral column in normal phase mode. The first mobile ...

    Authors: Ola Ahmed Saleh, Amr Mohamed Badawey, Hassan Y. Aboul-Enein and Marwa Ahmed Fouad
    Citation: BMC Chemistry 2023 17:22
  6. The optimization of the radiolabeling yield of carvedilol with iodine-131 was described. Dependence of the labeling yield of [131I]iodocarvedilol on the concentration of carvedilol, chloramine-T content, pH of th...

    Authors: M. A. Motaleb, K M Attalah, H A Shweeta and I. T. Ibrahim
    Citation: BMC Chemistry 2023 17:21
  7. Daclatasvir dihydrochloride has important roles not only in the management of COVID-19 pandemic symptoms but also in the treatment of chronic hepatitis C infection.

    Authors: Rania A. Sayed, Ahmed R. Mohamed, Wafaa S. Hassan and Manal S. Elmasry
    Citation: BMC Chemistry 2023 17:20
  8. Cardiovascular disease medications such as aspirin (ASP), statins like atorvastatin (ATR), and blood pressure-lowering drugs including ACE inhibitors like ramipril (RAM) have been included in the World Health ...

    Authors: Nora A. Abdallah, Amina M. El-Brashy, Fawzia A. Ibrahim and Mohamed I. El-Awady
    Citation: BMC Chemistry 2023 17:19
  9. Gliflozins and gliptins are two distinct groups of pharmacological drugs that reduce blood glucose levels in individuals with type II diabetes in various ways that may perform their functions harmoniously. Tri...

    Authors: Eman A. Bahgat, Hisham Hashem, Hanaa Saleh, Ebraam B. Kamel and Maya S. Eissa
    Citation: BMC Chemistry 2023 17:18
  10. Simple, direct, rapid, and sensitive HPLC and spectrophotometric methods were established for simultaneous estimation of a novel combination of budesonide and azelastine (BUD/AZL) in their laboratory-prepared ...

    Authors: Mohammed E. A. Hammouda, Amal A. El-Masry, Saadia M. El-Ashry and Dalia R. El-Wasseef
    Citation: BMC Chemistry 2023 17:17
  11. This work is dedicated to the greenness estimation of three proposed spectrophotometric techniques [e.g., ratio difference (RD), mean centering of ratio spectra (MCR) and continuous wavelet transform of ratio ...

    Authors: Khadiga M. Kelani, Asmaa G. Gad, Yasmin M. Fayez, Amr M. Mahmoud and Ahmed M. Abdel-Raoof
    Citation: BMC Chemistry 2023 17:16
  12. Nucleic acid is the carrier of genetic information and the keymolecule in life science. It is important to establish a simple and feasible method for nucleic acid quantification in complex biological samples.

    Authors: Jia Xu, Yuan Yang, Juan Du, Hui Lu, Wenqi Gao, Hongjian Gong and HanXiao
    Citation: BMC Chemistry 2023 17:15
  13. Designing new, verified methodologies with a focus on sustainability, analytical efficiency, simplicity, and the environment has become a major priority for pharmaceutical quality control units. In this way, s...

    Authors: Hoda M. Marzouk, Nada S. Ayish, Badr A. El-Zeany and Ahmed S. Fayed
    Citation: BMC Chemistry 2023 17:14
  14. Molnupiravir is the first oral direct-acting antiviral prodrug recently approved for the COVID-19 pandemic. Here and for the first time, we present a novel, sensitive, robust, and simple silver-nanoparticles s...

    Authors: Ahmed R. Mohamed, Ebrahim Abolmagd, Israa M. Nour, Mohamed Badrawy and Mohamed A. Hasan
    Citation: BMC Chemistry 2023 17:13
  15. Nano graphene oxide/3-aminopyridine has been introduced as a new, efficient and robust heterogeneous organic catalyst for synthesis of spiro-indoline-pyranochromene derivatives. Nano graphene oxide/3-aminopyri...

    Authors: Soghra Khabnadideh, Khashayar Khorshidi and Leila Amiri-Zirtol
    Citation: BMC Chemistry 2023 17:12
  16. Nonsteroidal anti-inflammatory drugs (NSAIDs) have been the most commonly used class of medications worldwide for the last three decades.

    Authors: Mohammed Hawash, Nidal Jaradat, Murad Abualhasan, Murat Kadır Şüküroğlu, Mohammed T. Qaoud, Deniz Cansen Kahraman, Heba Daraghmeh, Leen Maslamani, Mais Sawafta, Ala Ratrout and Linda Issa
    Citation: BMC Chemistry 2023 17:11
  17. Ball mill is an effective, and green method for the synthesis of heterocyclic compounds in very good yields. This method is a simple, economical, and environmentally friendly process. In this work, an efficien...

    Authors: Dina Mallah and Bi Bi Fatemeh Mirjalili
    Citation: BMC Chemistry 2023 17:10
  18. Tobacco-free nicotine pouches is a novel category of oral nicotine-delivery products. Among current tobacco users such pouches may serve as a low-risk alternative to cigarettes or conventional, tobacco-based o...

    Authors: Susanne Back, Anna E. Masser, Lars E. Rutqvist and Johan Lindholm
    Citation: BMC Chemistry 2023 17:9
  19. The present work aims to investigate the ultrastructural changes in the fat body of fifth instar nymphs Schistocerca gregaria (Orthoptera: Acrididae) treated with zinc chromium oxide (ZnCrO). The nanoparticles (N...

    Authors: Fatma M. Hashem, Elsayed Elgazzar and Wageha A. Mostafa
    Citation: BMC Chemistry 2023 17:7
  20. Synthetic strategy for the synthesis of thiophene 2-carboxamide derivatives substituted with hydroxyl, methyl and amino groups at position-3 was proposed. The strategy includes the cyclization of the precursor...

    Authors: Heba M. Metwally, Norhan A. Khalaf, Ehab Abdel-Latif and Mohamed A. Ismail
    Citation: BMC Chemistry 2023 17:6
  21. Tannery industries’ effluent contains a high concentration of Cr (VI) which has the potential to affect the environment and public health. Therefore, this study aimed to investigate the optimization of Cr (VI)...

    Authors: Jemal Fito, Solomon Tibebu and Thabo T. I. Nkambule
    Citation: BMC Chemistry 2023 17:4
  22. In this study, Superparamagnetic magnetite nanoparticles (SPMNPs) are used in a new way as direct nanocarrier for Doxorubicin hydrochloride (DOX) via the functionalization of their surface with tri-sodium citr...

    Authors: Magda Ali Akl, Amira Mostafa Kamel and Mahmoud Ahmed Abd El-Ghaffar
    Citation: BMC Chemistry 2023 17:3
  23. The Knoevenagel-Michael cyclocondensation of barbituric acid/1,3-dimethylbarbituric acid, malononitrile, and arylaldehyde derivatives was used to construct a multicomponent green tandem method for the metal-fr...

    Authors: Farzaneh Mohamadpour
    Citation: BMC Chemistry 2023 17:2
  24. Converting seed coat peas (hulls) (SCP) into beneficial products provides a solution for waste treatment. This study aimed to investigate the phytoconstituents and biological activities of SCP extract. Phytoch...

    Authors: Hanaa S. S. Gazwi, Maha O. A. Omar and Magda E. Mahmoud
    Citation: BMC Chemistry 2023 17:1
  25. Desmopressin acetate (DPA) is a synthetic analogue of vasopressin used in the treatment of diabetes insipidus, bedwetting, hemophilia A, and elevated levels of urea in the blood. Sensitive and selective stabil...

    Authors: Khadiga M. Kelani, Ahmed M. Wafaa Nassar, Gamal A. Omran, Samir Morshedy and Wael Talaat
    Citation: BMC Chemistry 2022 16:117
  26. The discoveries recommend that the photoinduced conditions of fluorescein-determined go about as impetus for photochemically combining polysubstituted quinolines in ethanol at room temperature under air enviro...

    Authors: Farzaneh Mohamadpour
    Citation: BMC Chemistry 2022 16:116
  27. A simple and precise analytical approach developed for single and simultaneous determination of resorcinol (RC) and hydroquinone (HQ) in pharmaceutical samples using carbon paste electrode (CPE) modified with ...

    Authors: Ebrahim Nabatian, Mahdi Mousavi, Mostafa Pournamdari, Mehdi Yoosefian and Saeid Ahmadzadeh
    Citation: BMC Chemistry 2022 16:115
  28. An isocratic RP-HPLC method has been developed for the separation and determination of methocarbamol (MTL), indomethacin (IND), and betamethasone (BET) in combined dosage form using an Inertsil ODS-3v C18 (250...

    Authors: Ehab F. Elkady, Marwa A. Fouad and Ayoub N. Mozayad
    Citation: BMC Chemistry 2022 16:114
  29. In this study, we have used hydroxyethyl cellulose (HEC) to prepare antimicrobial films for multipurpose applications. Using HEC gives mangiferin powder (M) mechanical properties, while mangiferin powder gives...

    Authors: Hebat-Allah S. Tohamy, Mohamed El-Sakhawy, Hossam M. El-Masry, Ibrahim A. Saleh and Mona M. AbdelMohsen
    Citation: BMC Chemistry 2022 16:113
  30. Ludwigia adscendens subsp. diffusa (Onagraceae), an important aquatic herb widely distributed in the Nile River and canals in Egypt. The goal of the current study is to investigate the phytochemical composition o...

    Authors: Mostafa H. Baky, Mohamed R. Elgindi, Enas M. Shawky and Haitham A. Ibrahim
    Citation: BMC Chemistry 2022 16:112
  31. Quinolone is a privileged scaffold in medicinal chemistry and 4-Quinolone-3-Carboxamides have been reported to harbor vast therapeutic potential. However, conversion of N-1 substituted 4-Quinolone 3-Carboxylat...

    Authors: Muhammad Shoaib Ali Gill, Nursyuhada Azzman, Sharifah Syed Hassan, Syed Adnan Ali Shah and Nafees Ahemad
    Citation: BMC Chemistry 2022 16:111
  32. In the present study, a green surface modification of gold nanoparticles (GNPs) using chondroitin sulfate (CHS) and chitosan (CS) to deliver an extended-release of doxorubicin (DOX) was proposed. Following syn...

    Authors: Maryam Asariha, Seyed Hossein Kiaie, Sepideh Izadi, Faezeh H. Pirhayati, Mehdi Fouladi and Maryam Gholamhosseinpour
    Citation: BMC Chemistry 2022 16:110
  33. This research work focuses on the synthesis, characterization through spectra (FT-IR, UV–vis, and 1H-NMR) investigations, and the use of density functional theory (DFT) along with time-dependent density functiona...

    Authors: Mbang I. Ofem, Hitler Louis, John A. Agwupuye, Umar S. Ameuru, Gloria C. Apebende, Terkumbur E. Gber, Joseph O. Odey, Neksumi Musa and Ayi A. Ayi
    Citation: BMC Chemistry 2022 16:109
  34. Etoricoxib (ETO), Paracetamol (PCM), and two toxic impurities for Paracetamol impurity K (4-aminophenol (PAP)) and impurity E (para-hydroxy acetophenone (PHA)) were separated using a simple and selective HPLC ...

    Authors: Mona A. Abdel Rahman, Mohamed R. Elghobashy, Hala E. Zaazaa, Shimaa A. Atty and Sally S. El-Mosallamy
    Citation: BMC Chemistry 2022 16:108
  35. Quinazolinones are a diverse group of nitrogen-containing heterocyclic compounds with promising antimalarial and antileishmanial activities. Herein, some 3-aryl-2-styryl substituted-4(3H)-quinazolinones were synt...

    Authors: Girma Worku Seifu, Yihenew Simegniew Birhan, Botros Youssef Beshay, Ariaya Hymete and Adnan Ahmed Bekhit
    Citation: BMC Chemistry 2022 16:107
  36. In this study, the ethyl acetate fraction of Myristica fragrans Houtt. was investigated for its in vitro anticholinesterase activity as well as neuroprotectivity against H2O2-induced cell death in PC12 neuronal c...

    Authors: Arezoo Rastegari, Azadeh Manayi, Mahdi Rezakazemi, Mahdieh Eftekhari, Mahnaz Khanavi, Tahmineh Akbarzadeh and Mina Saeedi
    Citation: BMC Chemistry 2022 16:106
  37. In this work, nickel oxide nanoparticles were prepared by polyol mediated aqueous route of sol–gel process using nickel nitrate hexahydrate as precursor, a mixture of isopropyl alcohol and water as solvent and...

    Authors: Samreen Zahra, Waneeza Shahid, Chaudhry Athar Amin, Sarwat Zahra and Bushra Kanwal
    Citation: BMC Chemistry 2022 16:105
  38. A new series of (E)-2-(3-(substitutedstyryl)-5-(substitutedphenyl)-4,5-dihydropyrazol-1-yl)benzo[d]thiazole derivatives was synthesized and the chemical structures of synthesized compounds were deduced by IR and ...

    Authors: Manoj Kumar, Vijay Kumar, Vikramjeet Singh and Samridhi Thakral
    Citation: BMC Chemistry 2022 16:103
  39. A precise, sensitive eco-friendly, simple, rapid, and derivative spectrofluorimetric method was developed to quantify edoxaban tosylate monohydrate in pure form and pharmaceutical dosage form. Sudden death due...

    Authors: Mohamed Rizk, Maha Mahmoud Abou El-Alamin, Ola Abd Elkhalek and Aliaa I. Shallan
    Citation: BMC Chemistry 2022 16:102
  40. Turkevich gold nanospheres are the original nanospheres that have been modified over time. Its combination with targeting medications such as alendronate, memantine, and tobramycin will provide additional bene...

    Authors: Dina M. Eissa, Mokhtar M. Mabrouk, El Zeiny M. Ebeid and Mohamed A. Abdel Hamid
    Citation: BMC Chemistry 2022 16:101
  41. A series of quinazolinone derivatives (7a7h) were synthesized as antiproliferative agents. All compounds, were synthesized through three steps method and structurally evaluated by FTIR, 1H-NMR, 13CNMR and Mass s...

    Authors: Leila Emami, Soghra Khabnadideh, Zahra Faghih, Farnoosh Farahvasi, Fatemeh Zonobi, Saman Zare Gheshlaghi, Shadi Daili, Ali Ebrahimi and Zeinab Faghih
    Citation: BMC Chemistry 2022 16:100
  42. A validated, sensitive, and simple spectrofluorimetric method was developed for the analysis of two important CNS-acting drugs, olanzapine and diazepam, in their commercial tablets without the need for any pre...

    Authors: Galal Magdy, Noura Said, Ramadan A. El-Domany and Fathalla Belal
    Citation: BMC Chemistry 2022 16:98
  43. The development of new antidiabetes agents is necessary to obtain optimal glycemic control and overcome its complications. Different quinazolin-4(3H)-one bearing phenoxy-acetamide derivatives (7a–r) were designed...

    Authors: Mahshid Moheb, Aida Iraji, Navid Dastyafteh, Minoo Khalili Ghomi, Milad Noori, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Fatemeh Rasekh, Bagher Larijani, Kamiar Zomorodian, Seyed Esmaeil Sadat-Ebrahimi and Mohammad Mahdavi
    Citation: BMC Chemistry 2022 16:97
  44. Isodon amethystoides (Lamiaceae) is a popular plant in folk medicine in the southern provinces of China. Our phytochemical investigation of the twigs and leaves of this plant led to the discovery of five new dite...

    Authors: Chenliang Zhao, Lang Zhou, Wenjian Xie, Lihan Zhao, Chiyuan Zhang, Kang He, Jianghai Ye, Jingjie Zhang, Lutai Pan, Juan Zou and Hongjie Zhang
    Citation: BMC Chemistry 2022 16:96

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