Adjusted green spectrophotometric determination of favipiravir and remdesivir in pharmaceutical form and spiked human plasma sample using different chemometric supported models

Table 4 Performance and validation data of the described models for determination of FV and RV

Parameters	CLS		PCR		PLS
Parameters	FV	RD	FV	RD	FV	RD
Wavelength scanning range	220–400	220–400	220–400	220–400	220–400	220–400
Linearity range (µg/mL)	1–17	1–17	1–17	1–17	1–17	1–17
LOD (µg/mL)	0.133	0.356	0.132	0.215	0.265	0.177
LOQ (µg/mL)	0.407	1.079	0.401	0.652	0.804	0.537
Accuracy (%R)^a	100.79	100.94	99.78	99.69	98.77	100.23
Precision (%RSD)^b
Repeatability	0.934	0.870	0.870	0.721	0.658	0.524
Intermediate Precision	1.043	0.987	0.987	1.023	0.871	0.742

ISSN: 2661-801X