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Table 6 Antiviral activity of compound 15 N against Hepatitis A virus

From: Attractive study of the antimicrobial, antiviral, and cytotoxic activity of novel synthesized silver chromite nanocomposites

Treatment

MNCC

(µg/ml)

Antiviral

effect on HAV

(%)

Antiviral

effect on HAV

(Qualitative)#

Antiviral Efficiency

EC50

CC50

SI

Amantadine

(control)

130

86.91 ± 5.57

++++

8.48 ± 0.50

325.61 ± 16.9

38.39

15 N

60

7.24 ± 0.64*

+

408.14 ± 21.60*

280.36 ± 19.3*

0.69

  1. Data is displayed as mean (n = 3) ± standard deviation
  2. *: represents significant difference (P < 0.05), as compared to the corresponding controls, according to independent t-test. #Where: (+): Weak antiviral activity (1- < 25%), and (++++): Excellent antiviral activity (75–100%)
  3. Where: ( +): Weak antiviral activity (1– < 25%), and (++++): Excellent antiviral activity (75–100%)