Skip to main content

Advertisement

  • Research article
  • Open Access

Synthesis, characterization, electrospinning and antibacterial studies on triphenylphosphine-dithiphosphonates Copper(I) and Silver(I) complexes

  • 1Email author,
  • 2,
  • 3 and
  • 3
Chemistry Central Journal20148:18

https://doi.org/10.1186/1752-153X-8-18

©  Karakus et al.; licensee Chemistry Central Ltd. 2014

  • Received: 17 December 2013
  • Accepted: 5 March 2014
  • Published:

Abstract

Background

The novel amido and O-ferrocenyldithiophosphonates [FcP(S)(SH)(NHR1)] (Fc = Fe(η5-C5H5)(η5-C5H4), R1 = 1-(4-fluorophenylethyl and benzyloxycyclopentyl) and [FcP(S)(OR2)S−][H3N+C(CH3)3] (R2 = myrtanyl) were synthesized by the reaction of [(FcPS2)]2 (Fc = Fe(η5-C5H5)(η5-C5H4)) and chiral amines, such as (S)–(−)-1-(4-fluorophenylethyl) amine and (1S,2S)-(+)-benzyloxycyclopentyl amine, and of (1S), (2S), (5S)-myrtanol in toluene. The reaction of ferrocenyldithiophosphonates and [Cu(PPh3)2]NO3 or AgNO3 and PPh3 gave rise to copper(I) and silver(I) complexes in THF. [Ag2{FcP(OMe)S2}2(PPh3)2] and [Cu(PPh3)2]NO3 were embedded into nanofibers and their antimicrobial activities on fibers were also investigated.

Results

The compounds have been characterized by elemental analyses, IR, NMR (1H-, 31P-) spectroscopy as well as MS measurements. Nanofibers were obtained by electrospinning method which is the simplest and most effective method to produce nanoscale fibers under strong electrical field. Antimicrobial activity of the compound 5, [Ag2{FcP(OMe)S2}2(PPh3)2], and [Cu(PPh3)2]NO3 on fibers were studied.

Conclusions

In this study, the new dithiophosphonate ligands were synthesized and utilized in the preparation of copper(I) and silver(I) complexes with ferrocenyldithiophosphonate and triphenylphosphine. Then, the compounds [Ag2{FcP(OMe)S2}2(PPh3)2] and [Cu(PPh3)2]NO3 were added into the PAN solutions (Co-PAN dissolved in dimethylacetamide) and the solutions were electrospun onto microscope slides and PP meltblown surfaces. Antimicrobial activity of the compounds [Ag2{FcP(OMe)S2}2(PPh3)2] and [Cu(PPh3)2]NO3 on fibers were determined in vitro against two indicator strains; M. luteus NCIB and E. coli ATCC25922. The obtained results indicated that these metals showed moderate level antimicrobial activities.

Graphical Abstract image

Keywords

  • Dithiophosphonates
  • Triphenylphosphine
  • Copper(I) and Silver(I) complexes
  • Nanofiber
  • Electrospinning
  • Antibacterial

Introduction

Metallic silver and copper are natural antimicrobial agents and historically recognized [1, 2]. These agents have been added into many polymer solutions, such as polyacrilonitrile (PAN), polyvinyl alcohol (PVA), Poly(N-vinylpyrrolidone), polylactic acid (PLA), to produce nanofibers with electrospinning method [3–10].

Electrospinning is a simple method to produce micro or nanoscale fibers. Nanofibers, due to their high surface area and porosity, find applications in energy storage, healthcare, biotechnology, environmental engineering, defense and especially filtration [11]. Electrospinning process uses a high voltage electric field to produce electrically charged jets from polymer solution. Polymer solution on tip of a syringe or pipette ejects toward opposite charged collector when overcome surface tension. Polymer chain entanglements prevent jets from breaking off and create fiber form. Because of evaporation and air drag, jets split into smaller diameters [12]. Process parameters are divided into; solution parameters which include viscosity, surface tension, electrical conductivity; processing conditions which include applied voltage, tip to collector distance, feeding amount and type; and ambient conditions which include temperature and moisture [13].

Dithiophosphonates are an important class in organophosphorus chemistry due to utilising in agricultural, medicinal and technological field [14–35]. It has been known that a considerable number of dithiophosphonates and their metal complexes have been easily synthesized by the reaction Lawesson’s reagent or Ferrocenyl Lawesson’s reagent and the respective alcohols or amines due to a ring opening reaction by nucleophilic attack [30–32]. However, there is no study on nanofibers of dithiophosphonates by using electrospinning method.

In the present work, we report the synthesis of novel dithiophosphonates and their metals complexes with dithiophosphonates and triphenylphosphine. All compounds were characterized by elemental analyses, IR, NMR (1H-, 31P-) spectroscopy as well as MS measurements. The compounds [Ag2{FcP(OMe)S2}2(PPh3)2] and [Cu(PPh3)2]NO3 added into PAN polymer solutions and mixed. Mixed polymer solutions were electrospun onto microscope slides and PP (polypropylene) meltblown surfaces. Meltblown is very commonly used textile nonwoven structure to support and protect fine fibers, especially in filtration. Antibacterial activities of those nanofibers were investigated.

Result and discussion

Synthesis and characterization

Amido and O-ferrocenyldithiophosphonates have been synthesized from Ferrocenyl Lawesson’s reagent and amines or (1S,2S,5S)- (−)- O-myrtanol (Scheme 1). The Ferrocenyl Lawesson’s reagent was reacted with (1S,2S,5S)- (−)- O-myrtanol and a crude dithiophosphonic acid was formed and then was treated with tert-butyl amine in order to convert it to its suitable salt 1. In the case of amidodithiophoshonates 2 and 3 (Scheme 1), they were obtained as air stable solids [35]. The compound 5 was prepared by the reaction of (R) - (+) – 1 - phenylethyl amidoferrocenyldithiophosphonate [35] and AgNO3 in toluene and MeOH mixture (Scheme 2).
Scheme 1
Scheme 1

Synthesis of 1–3 and assigment scheme for ferrocene group.

Scheme 2
Scheme 2

Synthesis of [Ag 2 {FcP(OMe)S 2 } 2 (PPh 3 ) 2 ] 5.

The IR spectrum of the ligands and their complexes showed two characteristic bands at around 692–642 cm−1 and 582 – 515 cm −1 which are assigned to νas(PS2) and νs(PS2), respectively [36, 37].

Mass spectra of the compound 1 – 5 exhibited m/z values for identifiable certain fragments. Specific rotations of all compounds showed that only one optical isomer was formed.

The 31P NMR spectra of the ligands 2 and 3 were measured in DMSO-d6 and showed two separate sets of signals which were shifted to 61.80 ppm (JPN-H = 41.7 Hz for 2) and 62.09 ppm (JPN-H = 38.2 Hz for 3) [35, 38]. A very small signal was observed in the 31P NMR spectra of the ligands 2 and 3 due to probably neutral and zwitter ion form in the DMSO-d6 solution (see Scheme 1 for two isomer of 2 and 3).

All ligands 1–3 reported here have been characterized by elemental analysis, IR, NMR and mass spectroscopy (Additional file 1). However, the 31C-NMR spectra of the ligands 2 and 3 did not measured due to decomposed in the DMSO-d6.

The synthesis of copper(I) and silver(I) complexes with ferrocenyldithiophosphonate and triphenylphosphine have been described and also characterized by elemental analyses, IR, NMR and MS spectroscopies (Additional file 1). The synthesis of copper(I) complexes were performed by the reaction of [Cu(PPh3)2]NO3 and the ligands (Scheme 3).
Scheme 3
Scheme 3

Synthesis of copper(I) complex 4.

The complex 4 was obtained as yellow-orange solid. The 31P NMR spectrum of 4 showed two signals at 97.8 and −2.9 ppm as expected [36] which were assigned to PS2 and PPh3, respectively. The Cu(I) and Ag(I) complexes of 2 and 3 also showed two signals in the 31P NMR spectrum as expected. However, other spectroscopic data were not satisfied. The 31P NMR spectra of [Ag2{FcP(OMe)S2}2(PPh3)2] 5 was measured in CDCl3 and observed two signal at 92.82 (PS2) and 6.03 (PPh3) ppm.

Electrospinning studies

A comparative study on Silver(I) and Copper(I)- triphenylphosphine derivatives was performed and developed for the application of electrospun nanofibers. Figure 1 shows the compound [Ag2{FcP(OMe)S2}2(PPh3)2] added PAN nanofibers on a microscope slide and PP meltblown surface. Average fiber diameter on microscope slide was measured about 1 micron which was higher than expected average fiber diameter. Occasional electrospraying occurred as in Figure 1-b, because of aggregation of the compound [Ag2{FcP(OMe)S2}2(PPh3)2] particles.
Figure 1
Figure 1

[Ag 2 {FcP(OMe)S 2 } 2 (PPh 3 ) 2 ] added; a) electrospunned PAN fibers on glass, b) electrosprayed PAN particules on nonwoven surface.

Figure 2 shows [Cu(PPh3)2]NO3 added PAN nanofibers on a microscope slide and PP meltblown surface. Cu particles on nanofiber surface can be seen from SEM images as in Figure 2-a. Average PP meltblown fiber diameter was measured about 15 micron.
Figure 2
Figure 2

[Cu(PPh 3 ) 2 ]NO 3 added electrospunned PAN fibers; a) on glass, b) on nonwoven surface.

Antibacterial activities

Antimicrobial activities of the compounds [Ag2{FcP(OMe)S2}2(PPh3)2] and [Cu(PPh3)2]NO3 were determined first on agar media against two indicator strains; M. luteus NCIBM and E. coli ATCC25922. According to the well diffusion assay on agar media, [Ag2{FcP(OMe)S2}2(PPh3)2] and [Cu(PPh3)2]NO3 showed medium level of antimicrobial activities against both strains (Figure 3). When the control compounds (not including Cu or Ag derivatives) were used for the same method, no inhibition zone or no antibacterial activity was occurred meaning that the relevant antimicrobial activities were mainly due to incorporated elements of Cu or Ag.
Figure 3
Figure 3

Antimicrobial activity of [Ag 2 {FcP(OMe)S 2 } 2 (PPh 3 ) 2 ] and [Cu(PPh 3 ) 2 ]NO 3 .

The control compounds and the compounds embedded fibers on meltblown surfaces were tested for inhibition of E. coli ATCC25922 in submerged bacterial solution. The highest inhibition (32.5 ± 2.1%) on E. coli was achieved with the compound [Ag2{FcPS2(OMe)}2(PPh3)2]. On the other hand, [Cu(PPh3)2]NO3 provided 19.4 ± 3.2% inhibition on E. coli while the control compounds showed no inhibition.

In this study, the compounds showed better antibacterial activities on agar media because of diffusion. However when the compounds embedded into fibers, they showed antibacterial activities only in contact with bacteria. Even though there was limited antibacterial activity, these metals could be used on fibers with dithiphosphonate and phosphine complexes for antibacterial applications.

It is generally believed that heavy metals react with proteins by combining the thiol (SH) groups, which leads to the inactivation of the proteins [39]. Therefore Ag and Cu could maintain their antimicrobial activity in the complexes of dithiphosphonate and phosphine. This is significant especially for using these metals as embedded in fibers, although they have limited antibacterial activity [40, 41].

Experimental

Materials and method

Solvents were distilled before used. The compounds 4 and 5 were carried out under N2 atmosphere. All other chemicals were purchased from commercial sources and used directly without further purification. [FcPS2]2 (Fc: Fe(η5-C5H5)(η5-C5H4) and [Cu(PPh3)2]NO3 were prepared as described in the literature [32, 42], respectively. Elemental analyses were determined with a GmbH varioMICRO CHNS apparatus. Melting points were determined by using Electrotermal apparatus. NMR spectra were recorded on a Bruker AVANCE DRX 400 NMR spectrometer and Jeol GSX 270 in CDCl3 and d6-DMSO. IR spectra was measured on a Perkin-Elmer 2000 FTIR spectrophotometer (4000 – 400 cm−1). Mass spectra were recorded with an AGILENT 1100 MSD and Waters machines. Optical rotation values were determined with an automatic digital ADP 440+ polarimeter.

Electrospinning

The co-polymer polyacrylonitrile (PAN) and solvent dimethylacetamide (DMAc) were obtained from “AKSA acrylic chemistry company”. 15% polymer was dissolved in 85% solvent (w/w-weight by weight basis) at 80–100°C and stirred at least 4 hours. Polymer solution was prepared for electrospinning process by feeding into a pipette. Matsusada AU-40-0.75 high voltage supply were used to create electric field. Tip to collector distance was adjusted for 12 cm and voltage was adjusted 30 kV between the electrodes (Figure 4).
Figure 4
Figure 4

Electrospinning method.

Antibacterial activity

Two different antimicrobial test methods were used. Firstly the antimicrobial activity of synthesized compounds was determined by using well diffusion assay [43]. After filter sterilization of relevant compounds, approximately 100 μl was filled to the wells which had been prepared previously by overlaying LB soft agar including the indicator strains Micrococcus luteus NCBI8166 and Escherichia coliATCC25922 on to the Müller-Hilton agar plates, then 5 mm wells were created with cork borer respectively. DSMO was used for controlling. To test antimicrobial efficiency of relevant compounds on fibers, the dynamic assessment of antimicrobial activity was carried out according to the standard test method released from American Society for Testing and Materials (ASTM) for immobilized antimicrobial agents under dynamic contact (E2149-01). Test bacteria (Escherichia coli ATCC25922) were cultured in LB broth (Fluka) overnight inoculations at 37°C. Subsequently, bacterial culture was diluted in 0.3 mM KH2PO4 buffer until the solution has an absorbance of 0.28 ± 0.02 at 475 nm as measured spectrophotometrically to reach bacterial suspension (1.5-3.0×105 CFU ml−1). Rounds of fibers having total 4 in.2 treated surface area were inoculated with 50 ± 0.5 ml of bacterial suspension and incubated at 37°C 1 h ±5 min. Standard plate counts were performed after decimal dilution of the samples in 9 ml of 0.1% peptone water. The percent inhibition rate (%) was calculated as formula of (N1-N2/N1) × 100, where N1 and N2 represent the number of colonies on the plates before and after inhibition, respectively. Untreated fibers were used as a negative control.

Synthesis of t-Butyl ammonium salt of (1S,2S,5S)- (−)- O-myrtanyl ferrocenyl dithiophosphonate (1)

2,4-Bis(ferrocenyl)-1,3,2,4-dithiadiphosphetane-2,4-disulfide [FcPS(μ-S)]2 (1.80 g, 3.21 mmol) was reacted with 1S,2S,5S)-(−)-myrtanol (1.05 g, 6.42 mmol) in toluene (20 mL). The mixture was refluxed until all solids had dissolved. The dark brown solution was cooled to rt, filtered and treated with excess tert-butyl amine. The product was precipitated in freezer from toluene as a yellow solid, which was isolated by filtration, washed with toluene and n-hexane and then dried in air. Yield: 2.10 g 65%, m.p.: >187(dec.)°C. [α]58925 = −3.61 (c = 0.55 in THF). IR(KBr, cm−1) νmax: 648 (s,PS2, asym) and 582 (m, PS2, sym). 1H NMR (DMSO-d6, ppm) δ: 4.42 (br, 2H, C5H4), 4.23 (s, 5H, C5H5), 4.21 (br, 2H, C5H5), 4.18 (br, 2H, OCH2), 1.80-1.25 (m, 9H in myrtanyl group), 1.18 (s, 9H, tBu), 1.02 (s, 3H, CH3), 1.01(s, 3H, CH3). 13C NMR (DMSO-d6, ppm) δ: 90.94 (d, C1; ipso-C in C5H4, 1JP,C = 124.7 Hz), 84.23(d, 2JP,C = 7.9 Hz), 71.30 (d, C2 and C2′, 2JP,C = 13.9 Hz), 70.06 (s, C5H5), 69.71(d, 4JP,C = 2.7 Hz), 68.91 (d, C3 and C3′, 3JP,C = 4.9 Hz), 49.81 (s, tBut), 49.12 (d, 3JP,C = 5.2 Hz), 48.37, 41.50, 29.95 (s, tBu), 29.71, 26.78, 26.41, 22.23, 20.8 ppm. 31P NMR (DMSO-d6 ppm) δ: 105.46. MS (ESI): m/z 433.1 [M–(H3N+C(CH3)3]. Anal. Calcd. for C24H38FeNOPS2: C, 56.80; H, 7.55; N, 2.76; S, 12.64%. Found: C, 57.08; H, 7.38; N, 2.72; S, 12.18%.

Synthesis of (S) –(−)-1-(4-fluorophenylethyl)–amidoferrocenyldithiophoshonate (2)

[FcP(S)(μ-S)]2 1.50 g (2.67 mmol) was treated with (S) – (−)-1-(4-fluorophenylethyl) amine (0.745 g, 5.35 mmol) in a 1:2 ratio in toluene (25 mL) to give the corresponding amidoferrocenyldithiophosphonate. The reaction was carefully heated until all the solids dissolved and a brown solution was obtained and then a solid product was formed, which was isolated by filtration. The product was washed with petroleum ether (40–60°C). The yellow crystalline product was dried under vacuum. Yield: 1.57 g, 70%, m.p.: 169°C. [α]58925 = 75 (c = 0.08 in THF). IR(KBr, cm−1) νmax: 645 (s, PS2, asym) and 526 (m, PS2, sym). 1H NMR (DMSO-d6 ppm) δ: 7.63 (br, 2H, arom.), 7.25 (br, 2H, arom.), 4.56 (br, 2H, C5H4), 4.43 (br, 2H, C5H4), 4.37 (s, 5H, C5H5), 2.50 (s, 3H, CH3), 1.59 (s, 1H, CH). 31P NMR (DMSO-d6 ppm) δ: 61.80 (d, JPNH = 41.7 Hz) ppm. MS (ESI): m/z = 401.95 [M-F]+. Anal. Calcd. for C18H19NFPS2Fe: C, 51.56; H, 4.57; N, 3.34; S, 15.29%. Found: C, 51.71; H, 5.07; N, 3.54; S, 14.20%.

Synthesis of (1S,2S)-(+)-benzyloxycyclopentyl–amidoferrocenyldithiophoshonate (3)

Compound 3 was prepared in the same manner as compound 2, from [FcP(S)(μ-S)]2 (1.00 g, 1.78 mmol) and 1S,2S-(+)-benzyloxycyclopentyl amine 0.68 g (3.56 mmol) in toluene (25 mL). Yield: 1.19 g (76%), m.p.: 174–176°C. [α]58925 = 53.33 (c = 0.15 in THF). IR(KBr, cm−1) νmax: 645 (s, PS2, asym) and 525 (m, PS2, sym). 1H NMR (DMSO-d6 ppm) δ: 8.29(br, 1H, NH), 7.37(br, 5H, arom.), 4.54 (br, s, 2H, C5H4), 4.21 (br, s, 5H, C5H5), 4.18 (br, s, 2H, C5H4), 3.99 (br, 2H, OCH2), 3.80 – 1.69(br, m, 8H, C5H8 group). 31P NMR (DMSO-d6 ppm) δ: 62.09 ppm (JPN-H = 38.2 Hz) ppm. MS (ESI): m/z = 296.86 [M-C5H8OCH2C6H5]+. Anal. Calcd. for C22H27NOPS2Fe: C, 56.06; H, 5.59; N, 2.97%. Found: C, 60.07; H, 6.34; N, 3.30%.

Synthesis of [Cu{Fe(η5-C5H5)(η5-C5H4P(OR)S2)(PPh3)2}] (R = myrtanyl) (4)

A solution of [Cu(PPh3)2NO3] (0.13 g, 0.20 mmol) in THF(10 mL) was added dropwise to a solution of (1S, 2S, 5S)–O-myrtanyl-ferrocenyldithiophoshonate 1 (0.10 g, 0.20 mmol) in THF (10 mL) and stirred at r.t. for 2 h. A yellow-orange solution was observed. The reaction mixture was filtered and the solvent was removed under reduced pressure. A yellow-orange crystalline product was isolated. Yield: 0.12 g, 60%, m.p.: 179–180°C. [α]58925 = 120 (c = 0.05 in THF). IR (KBr, cm−1) νmax: 642 (s, PS2, asym) and 515 (m, PS2, sym). 1H NMR (CDCl3, ppm) δ: 7.43 – 7.25 (m, 30H, arom.), 4.36 (br, 2H, C5H4), 4.25 (s, 2H, C5H5), 4.21 (s, 2H, C5H4), 3.80 (m, 2H, OCH2), 2.40–1.10 (m, 9H, in myrtanyl group), 1.24 (s, 3H,CH3), 0.87 (s, 3H, −CH3). 31P NMR (CDCl3, ppm) δ: 97.85 (PS2) and −2.87 (PPh3) ppm. Anal. Calcd. for C56H56OP3S2FeCu (1021.51 g.mol−1): C, 65.84; H, 5.52; S, 6.27%. Found: C, 65.49; H, 5.54; S, 5.93%.

Synthesis of [Ag{Fe(η5-C5H5)(η5-C5H4P(OR)S2)(PPh3)2}]2 (R = CH3) (5)

A mixture of AgNO3 (0.12 g, 0.70 mmol) and PPh3 (0.18 g, 0.70 mmol) in MeOH (20 mL) was added dropwise to a solution of the compound (R) - (+) – 1 - Phenylethyl amidoferrocenyldithiophosphonate [35] (0.28 g, 0.70 mmol) in toluene (25 mL) and stirred for 2 h. A yellow precipitate product was immediately formed. The product was filtered, washed with petroleum ether(40–60°C) and dried in air. Yield: 0.38 g (79%). M.p.:>160°C(dec.). IR(KBr, cm−1) νmax: 649 (νasym PS2) and 560 (νsym PS2). 1H NMR (CDCl3, ppm) δ: 7.36 – 7.02 (m, 30H, arom.), 4.55 (br, 4H, 2× C5H4), 4.36 (br, 4H, 2xC5H4), 4.16 (s, br, 10H, 2xC5H5), 1.39 (d, br, 6H, 2xOCH3, 3JP,H = 5.4 Hz). 31P NMR (CDCl, ppm) δ: 97.82 (PS2) and 6.03 (PPh3). MS (ESI) (m/z): 279.1 [FcPS2]+. Anal. Calc. for C58H54O2P4S4Fe2Ag2: C, 51.12; H, 3.99; S, 9.41. Found: C, 50.76; H, 3.96; S, 9.87%.

Conclusions

The new dithiophosphonate ligands were synthesized and utilized in the preparation of copper(I) and silver(I) complexes with ferrocenyldithiophosphonate and triphenylphosphine. Then, the compounds [Ag2{FcP(OMe)S2}2PPh3)2] and [Cu(PPh3)2NO3] were added into the PAN polymer solution (Co-PAN dissolved in dimethylacetamide) and the solution was electrospun onto microscope slide and PP meltblown surface producing fibers, average about 1 micron diameter. SEM images of these fibers show that compounds did not evenly distribute on fiber surface along the fiber length, meaning also not evenly distributed in polymer solution because of particles aggregation which caused electrospraying, as well. Antimicrobial activity of the compounds ([Ag2{FcPS2(OMe)}2(PPh3)2] and [Cu(PPh3)2]NO3) on fibers were determined in vitro against two indicator strains; M. luteus NCIB and E. coli ATCC25922. The obtained results indicated that these metals could be immobilized with the dithiophosphonate-phophine and showed moderate level antimicrobial activity.

Declarations

Acknowledgment

This study was supported by Turkish Council of Research and Technology, TUBITAK (Grant no: 107 T817).

Authors’ Affiliations

(1)
Department of Chemistry, Faculty of Arts&Sciences, Pamukkale University, Kinikli, 20075, Denizli, Turkey
(2)
Department of Textile Engineering, Faculty of Engineering, Pamukkale University, Kinikli, 20075, Denizli, Turkey
(3)
Department of Food Engineering, Faculty of Engineering, Pamukkale University, Kinikli, 20075, Denizli, Turkey

References

  1. Silvestry-Rodrigues N, Sicairos-Ruelas EE, Gerba EE, Bright KR: Silver as a disinfectant. Rev Environ Contam Toxicol. 2007, 191: 23-45.Google Scholar
  2. Grass G, Rensing C, Solioz M: Metallic copper as an antimicrobial surface. Appl Environ Microb. 2011, 77: 1541-1547. 10.1128/AEM.02766-10.View ArticleGoogle Scholar
  3. Yang QB, Li DM, Hong YL, Li ZY, Wang C, Qiu SL, Wei Y: Preparation and characterization of a pan nanofibre containing Ag nanoparticles via electrospinning. Synthetic Met. 2003, 137: 973-974. 10.1016/S0379-6779(02)00963-3.View ArticleGoogle Scholar
  4. Lee HK, Jeong EH, Baek CK, Youk JH: One-step preparation of ultrafine poly(acrylonitrile) fibers containing silver nanoparticles. Mater Lett. 2005, 59: 2977-2980. 10.1016/j.matlet.2005.05.005.View ArticleGoogle Scholar
  5. Jin WJ, Jeon HJ, Kim JH, Youk JH: A study on the preparation of poly(vinyl alcohol) nanofibers containing silver nanoparticles. Synthetic Met. 2007, 157: 454-459. 10.1016/j.synthmet.2007.05.011.View ArticleGoogle Scholar
  6. Hong KH: Preparation and properties of electrospun poly (vinyl alcohol)/silver fiber web as wound dressings. Polym Eng Sci. 2007, 47: 43-49. 10.1002/pen.20660.View ArticleGoogle Scholar
  7. Jin WJ, Lee HK, Jeong EH, Park WH, Youk JH: Preparation of polymer nanofibers containing silver nanoparticles by using poly (N- vinylpyrrolidone). Macromol Rapid Comm. 2005, 26: 1903-1907. 10.1002/marc.200500569.View ArticleGoogle Scholar
  8. Yousef A, Barakat NAM, Amna T, Al-Deyab SS, Hassan MS, Abdel-hay A, Kim HY: Inactivation of pathogenic Klebsiella pneumoniae by CuO/TiO2 nanofibers: A multifunctional nanomaterial via one-step electrospinning. Ceram Int. 2012, 38: 4525-4532. 10.1016/j.ceramint.2012.02.029.View ArticleGoogle Scholar
  9. Xu X, Yang Q, Wang Y, Yu H, Chen X, Jing X: Biodegradable electrospun poly(L-lactide) fibers containing antibacterial silver nanoparticles. Eur Polym J. 2006, 42: 2081-2087. 10.1016/j.eurpolymj.2006.03.032.View ArticleGoogle Scholar
  10. Han XJ, Huang ZM, Huang C, Du ZF, Wang H, Wang J, He CL, Wu QS: Preparation and characterization of electrospun polyurethane/inorganic-particles nanofibers. Polym Composites. 2045, 2012: 33-Google Scholar
  11. Ramakrishna S, Fujihara K, Teo WE, Yong T, Ma Z, Ramaseshan R: Electrospun nanofibers solving global issues. Mater Today. 2006, 9: 40-57.View ArticleGoogle Scholar
  12. Reneker DH, Chun I: Nanometre diameter fibres of polymer, produced by electrospinning. Nanotechnology. 1996, 7: 216-223. 10.1088/0957-4484/7/3/009.View ArticleGoogle Scholar
  13. Ramakrishna S: Introduction to Electrospinning and Nanofibers. 2005, Singapore: World Scientific PublishingView ArticleGoogle Scholar
  14. Contarini S, Tripaldi G, Ponti G, Lizzit S, Baraldi A, Paolucci G: Surface investigation of lubricant-metal interactions by synchrotron photoemission spectroscopy. Appl Surf Sci. 1997, 108: 359-364. 10.1016/S0169-4332(96)00678-2.View ArticleGoogle Scholar
  15. Fuller M, Yin Z, Kasrai M, Bancroft GM, Yamaguchi ES, Ryason PR, Willermet PA, Tan KH: Chemical characterization of tribochemical and thermal films generated from neutral and basic ZDDPs using X-ray absorption spectroscopy. Tribol Int. 1997, 30: 305-315. 10.1016/S0301-679X(96)00059-X.View ArticleGoogle Scholar
  16. Ma Q, Wang X-Y, Chen Q, Leung W-H, Zhang Q-F: Dinuclear ruthenium complexes containing tripodal dithiophosphonate ligands. Inorg Chimica Acta. 2011, 378: 148-153. 10.1016/j.ica.2011.08.044.View ArticleGoogle Scholar
  17. Karakus M, Loennecke P, Hildebrand M, Hey-Hawkins E: Chiral Heterobimetallic Gold(I) Ferrocenyldithiophosphonato Complexes. Z Anorg Allg Chem. 2011, 637: 983-987. 10.1002/zaac.201100004.View ArticleGoogle Scholar
  18. Karakus M, Lönnecke P, Hey-Hawkins E: Zwitterionic ferrocenyldithiophosphonates: the molecular structure of [FcP(S)S(OCH2CH2NH2Me)] [Fc = Fe(η5-C5H4)(η5-C5H5)]. Polyhedron. 2004, 23: 2281-2284. 10.1016/j.poly.2004.07.003.View ArticleGoogle Scholar
  19. Karakus M: Synthesis and characterization of novel organothiophosphorus compounds: X-ray crystal structure of H3COC6H4P(OC2H4S)(S) synthesized by a new method. Z Anorg Allg Chem. 2006, 632 (8–9): 1549-1553.View ArticleGoogle Scholar
  20. Karakus M, Yilmaz H, Bulak E, Lönnecke P: Bis{μ-[O–cyclopenthyl(4-methoxyphenyl)dithiophosphonato]1κ:S 2κ S -[O–cyclopenthyl(4-methoxyphenyl)dithiophosphonato]-1κ2S, S’}dizinc(II). Appl Organomet Chem. 2005, 19: 396-397. 10.1002/aoc.850.View ArticleGoogle Scholar
  21. van Zyl WE, Woollins JD: The coordination chemistry of dithiophosphonates: An emerging and versatile ligand class. Coord Chem Rev. 2013, 257: 718-731. 10.1016/j.ccr.2012.10.010.View ArticleGoogle Scholar
  22. van Zyl WE: Dithiophosphonates and related P/S-type ligands of group 11 metals. Comments Inorg Chem. 2010, 31: 13-45. 10.1080/02603590903510474.View ArticleGoogle Scholar
  23. van Zyl WE, Fackler JP: A general and convenient route to dithiophosphonate salt derivatives. Phosphorus, Sulfur, Silicon Relat Elem. 2000, 167: 117-132. 10.1080/10426500008082393.View ArticleGoogle Scholar
  24. van Zyl WE, López-de-Luzuriaga JM, Fackler JP: Luminescence studies of dinuclear gold(I) phosphor-1,1-dithiolate complexes. J Mol Struct. 2000, 516: 99-106. 10.1016/S0022-2860(99)00231-8.View ArticleGoogle Scholar
  25. van Zyl WE, Staples RJ, Fackler JP: Dinuclear gold(I) dithiophosphonate complexes: formation, structure, and reactivity. Inorg Chem Commun. 1998, 1: 51-54. 10.1016/S1387-7003(98)00013-6.View ArticleGoogle Scholar
  26. Pillay MN, Omondi B, Staples RJ, van Zyl WE: A hexanuclear gold(I) metallatriangle derived from a chiral dithiophosphate: synthesis, structure, luminescence and oxidative bromination reactivity. CrystEngComm. 2013, 15: 4417-4421. 10.1039/c3ce40496j.View ArticleGoogle Scholar
  27. Pollnitz A, Silvestru A, Gimeno MC, Laguna A: New gold(I) and silver(I) complexes with organophosphorus ligands with SPNSO skeleton. Crystal and molecular structures of monomeric [Au{(SPPh2)(O2SR)N}(PPh3)] (R = Me, C6H4Me-4) and dimeric [Ag{(SPPh2)(O2SPh)N}(PPh3)]2 · 2CH2Cl2]. Inorg Chimica Acta. 2010, 363: 346-352. 10.1016/j.ica.2009.10.022.View ArticleGoogle Scholar
  28. Liu S-L, Wang X-Y, Duan T, Leung W-H, Zhang Q-F: Hydrolysis and coordination behavior of ferrocenyl-phosphonodithiolate: Synthesis and structure of Cu4[FcP(OCH3)(μ-S)(μ3- S)]4 [Fc = Fe(η5-C5H4)(η5-C5H5)]. J Mol Struct. 2010, 964: 78-81. 10.1016/j.molstruc.2009.11.014.View ArticleGoogle Scholar
  29. Barranco EM, Crespo O, Gimeno MC, Jones PG, Laguna A: Unprecedented formation of novel phosphonodithioate ligands from diferrocenyldithiadiphosphetane disulfide. Inorg Chem. 2008, 47: 6913-6918. 10.1021/ic800470e.View ArticleGoogle Scholar
  30. Gray IP, Milton HL, Slawin AMZ, Woollins JD: Synthesis and structure of [Fc(RO)PS2]− complexes. Dalton Trans. 2003, 17: 3450-3457.View ArticleGoogle Scholar
  31. Gray IP, Milton HL, Slawin AMZ, Woollins JD: Synthesis and structure of [An(RO)PS2]− complexes. Dalton Trans. 2004, 16: 2477-2486.View ArticleGoogle Scholar
  32. Foreman MRSJ, Slawin AMZ, Woollins JD: The reaction of dithiadiphosphetane disulfides with dienes, alkenes and thioaldehydes. J Chem Soc Dalton Trans. 1999, 7: 1175-1184.View ArticleGoogle Scholar
  33. Solak S, Aydemir C, Karakus M, Lönnecke P: Novel Gold(I) and Silver(I) Complexes of Phosphorus-1,1,-dithiolates and Molecular Structure of [O, O’-(Bornyl)2PS2]H3NC(CH3). Chem Cen J. 2013, 7: 89-10.1186/1752-153X-7-89.View ArticleGoogle Scholar
  34. Herna’ndez-Galindo M del C, Jancik V, Moya-Cabrera MM, Toscano RA, Cea-Olivares R: 2D hydrogen bond networks in the crystals of [(NH4 center dot H2O)(2)][(RO)(Fc)P(S)(2)](2) (R = 3-(BzO)-Bz, 4-(n-Bu)-Bz, Bz = benzyl). J Organomet Chem. 2007, 692: 5295-5304. 10.1016/j.jorganchem.2007.08.014.View ArticleGoogle Scholar
  35. Karakus M: Synthesis and Characterization of Chiral Gold(I) Phosphine Complexes with New Dithiophosphorus Ligands. Phosphorus, Sulfur, Silicon Relat Elem. 2011, 186: 1523-1530. 10.1080/10426507.2010.521214.View ArticleGoogle Scholar
  36. Haiduc I, Mezei G, Micu – Semeniuc R, Edelman FT, Fisher A: Differing coordination modes of (O-alkyl)-p-ethoxyphenyldithiophosphonato ligands in copper(I), silver(I) and gold(I) triphenylphosphine complexes. Z Anorg Allg Chem. 2006, 632: 295-300. 10.1002/zaac.200500356.View ArticleGoogle Scholar
  37. Haiduc I, Sowerby DB, Lu S-F: Stereochemical aspects of phosphor-1,1- dithiolato metal complexes (dithiophosphates, dithiophosphinates): coordination patterns, molecular structures and supramolecular associations – I. Polyhedron. 1995, 14: 3389-3472. 10.1016/0277-5387(95)00108-5.View ArticleGoogle Scholar
  38. Cui Z, Miao Z, Zhang J, Chen R-Y: Synthesis of Diphenyl alpha-(O-phenyl bis(2-chloroethyl) amidophosphorylamino)- phosphonates. Phosphorus, Sulfur, Silicon Relat Elem. 2008, 183: 720-725. 10.1080/10426500701807616.View ArticleGoogle Scholar
  39. Silver S, Phung LT: Bacterial heavy metal resistance: new surprises Annu Rev Microbiol. Annu Rev Microbiol. 1996, 50: 753-789. 10.1146/annurev.micro.50.1.753.View ArticleGoogle Scholar
  40. Windler L, Height M, Nowack B: Comparative evaluation of antimicrobials for textile applications. Environ Int. 2013, 53: 62-73.View ArticleGoogle Scholar
  41. McArthur JV, Tuckfield RC, Baker-Austin C: Antimicrobial textiles. Handb Exp Pharmacol. 2012, 211: 135-152. 10.1007/978-3-642-28951-4_9.View ArticleGoogle Scholar
  42. Cotton FA, Goodgame DML: Tetrakis(triphenylphosphine)-Silver(I) and (Triphenylphosphine)-Copper(I) Complexes. J Chem Soc. 1960, 5267-5269.Google Scholar
  43. Schillinger U, Lücke FK: Lactic Acid Bacteria as Protective Cultures in Meat Products. Fleischwirtsch. 1990, 70: 1296-1299.Google Scholar

Copyright

© Karakus et al.; licensee Chemistry Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Advertisement

BMC Chemistry

ISSN: 2661-801X

Contact us