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Table 3 Application of the proposed method to the determination of the studied drugs in spiked human plasma.

From: Development and validation of a repharsed phase- HPLC method for simultaneous determination of rosiglitazone and glimepiride in combined dosage forms and human plasma

Compound

Concentration taken (μg/mL)

Concentration found (μg/mL)

% Found

Rosiglitazone

0.10

0.1058

105.80

 

0.25

0.2398

95.92

 

0.50

0.5017

100.34

 

0.75

0.7574

100.99

 

1.0

0.9964

99.64

X'

  

100.54

± SD

  

± 3.54

% RSD

  

3.52

% Error

  

1.57

Glimepiride

0.10

0.1072

107.20

 

0.25

0.2487

99.48

 

0.50

0.4925

98.50

 

0.75

0.7440

99.20

 

1.0

1.008

100.80

X'

  

101.04

± SD

  

± 3.55

% RSD

  

3.51

% Error

  

1.57