- Poster presentation
- Open Access
Theoretical structural metabolomics
© Apostolakis et al; licensee BioMed Central Ltd. 2009
- Published: 05 June 2009
- Reaction Center
- Molecular Modelling
- Specific Protein
- Single Molecule
The metabolome consists of all the low molecular weight molecules that are taken up, transformed and degraded by the cell. In many ways it represents the cells' interface with its chemical environment: It allows communication with the surroundings, and the gain of energy and building blocks. The metabolic state of the cell is mainly regulated by specific proteins, the enzymes, which catalyze the metabolic reactions, i.e. the transformation between different metabolites. Current developments in modelling may lead the way towards a cell wide analysis of the interaction between the proteome and the metabolome. This is the aim of theoretical structural metabolomics. In this talk I will outline a novel theoretical framework for analysing metabolic reactions and how they are catalysed by enzymes.
This article is published under license to BioMed Central Ltd.