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Table 3  Significance probability (p-value and F-value) of regression coefficients in the second-order polynomial models

From: Enhancing the efficacy of nano-curcumin on cancer cells through mixture design optimization of three emulsifiers

 

Main effects

Quadratic effects

X1X2

X1X3

X2X3

X1X2X3

Particle size (Y1,nm)

p-value

0.022

0.006

0.005

0.001

F-value

13.34

29.58

33.03

61.37

Zeta-potential (Y2, mV)

p-value

0.022

0.061

0.042

0.043

F-value

19.25

0.32

11.69

0.81