Table 3 Precision and accuracy for zanubrutinib of QC samples in rat plasma (n = 6)
Analyte | Concentration (ng/mL) | Intraday | Interday | ||||
|---|---|---|---|---|---|---|---|
Mean ± SD | RSD(%) | RE(%) | Mean ± SD | RSD(%) | RE(%) | ||
Zanubrutinib | 1 | 0.97 ± 0.10 | 9.8 | -2.7 | 1.00 ± 0.06 | 5.8 | -0.2 |
2 | 2.04 ± 0.11 | 5.2 | 2.2 | 2.02 ± 0.03 | 1.4 | 1.1 | |
40 | 40.29 ± 1.25 | 3.1 | 0.7 | 40.87 ± 0.62 | 1.5 | 2.2 | |
800 | 786.41 ± 68.89 | 8.8 | -1.7 | 803.16 ± 15.34 | 1.9 | 0.4 | |