Table 2 Recovery and matrix effect of zanubrutinib in rat plasma (n = 6)
Analyte | Concentration (ng/mL) | Recovery (%) | Matrix effect (%) | ||
|---|---|---|---|---|---|
Mean ± SD | RSD(%) | Mean ± SD | RSD(%) | ||
Zanubrutinib | 2 | 92.0 ± 10.2 | 11.1 | 104.4 ± 9.9 | 9.5 |
40 | 98.2 ± 11.4 | 11.6 | 97.5 ± 6.0 | 6.1 | |
800 | 97.0 ± 5.8 | 6.0 | 106.3 ± 6.6 | 6.2 | |