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Fig. 2 | BMC Chemistry

Fig. 2

From: A novel UHPLC‒MS/MS method for quantitative analysis of zanubrutinib in rat plasma: application to an in vivo interaction study between zanubrutinib and triazole antifungal

Fig. 2

Representative UHPLC–MS/MS chromatograms of zanubrutinib and ibrutinib (IS). (A) blank plasma; (B) a blank plasma sample spiked with LLOQ concentration levels of zanubrutinib and IS; (C) a rat plasma sample obtained 1 h after oral administration of zanubrutinib. The plasma concentration of zanubrutinib was 230 ng/mL

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