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Table 2 Determination of TCB and LVM in laboratory prepared mixtures and in Eradex Forte® suspension by the proposed methods

From: Spectrum subtraction as a complementary method for six resolution techniques resolving overlapping spectra; application to multicomponent veterinary formulation with greenness and whiteness assessment

TCB:LVM ratio

TCB

D0(304 nm)

D0(220 nm)

D1(310 nm)

D1(P 228–216 nm)

DD1(P230-220 nm)

RS-SS

RS-SS

CM-SS

FC-SS

DS-SS

DS-SS

D1 CM-SS

D1 FC-SS

 

R% ± S.D

2

3

98.49 ± 0.56

98.06 ± 0.05

98.01 ± 0.12

98.06 ± 0.06

101.33 ± 0.42

100.75 ± 0.41

100.80 ± 0.43

100.67 ± 0.53

99.93 ± 1.23

3

4

98.84 ± 0.33

98.18 ± 0.13

98.25 ± 0.14

98.26 ± 0.19

101.2 ± 0.34

100.28 ± 0.62

100.47 ± 0.43

99.57 ± 0.53

99.85 ± 1.29

1

1

99.86 ± 1.94

98.29 ± 1.99

100.58 ± 1.78

101.09 ± 1.94

101.18 ± 0.98

100.43 ± 0.69

100.99 ± 0.59

100.81 ± 0.49

99.99 ± 1.07

4.5

2.5

99.82 ± 0.17

98.61 ± 0.12

98.71 ± 0.21

98.54 ± 0.09

101.89 ± 0.35

100.41 ± 0.94

101.08 ± 0.96

101.53 ± 0.53

101.72 ± 0.72

*4

*2.5

98.57 ± 0.75

101.06 ± 1.97

100.3 ± 1.76

101.12 ± 1.94

100.31 ± 1.53

100.49 ± 0.62

101.81 ± 0.66

99.34 ± 0.53

99.53 ± 0.99

Eradex Forte® Suspension

 R% ± S.D

*4

*2.5

99.97 ± 1.42

100.19 ± 1.98

100.19

 ± 1.99

100.26 ± 1.53

100.55 ± 1.99

100.53 ± 1.99

100.47 ± 1.98

100.58 ± 1.89

98.819 ± 0.827

TCB:LVM ratio

TCB

LVM

CV

CNV

D0(214 nm)

FC-SS

D1(P221 nm)

DD1(P219 nm)

  

RS-SS

CM-SS

 

DS-SS

D1 CM-SS

D1 FC-SS

 

R% ± S.D

2

3

98.49 ± 0.55

99.13 ± 0.56

99.05 ± 0.89

100.12 ± 1.014

99.92 ± 1.35

101.2 ± 0.69

101.91 ± 0.41

101.76 ± 0.62

100.46 ± 0.85

3

4

98.88 ± 0.09

99.49 ± 0.09

99.31 ± 0.96

98.85 ± 1.29

98.88 ± 1.40

99.03 ± 0.89

98.96 ± 0.67

99.06 ± 0.51

99.102 ± 1.29

1

1

98.93 ± 1.83

99.61 ± 1.83

101.7 ± 0.50

101.2 ± 0.59

101.46 ± 0.97

100.77 ± 0.77

100.51 ± 0.97

100.39 ± 1.39

100.14 ± 1.44

4.5

2.5

100.11 ± 0.42

100.74 ± 0.42

101.68 ± 1.44

101.99 ± 1.35

101.76 ± 1.46

101.8 ± 0.83

100.54 ± 0.54

100.18 ± 0.83

100.61 ± 1.07

*4

*2.5

100.47 ± 1.19

101.13 ± 1.19

101.93 ± 1.07

101.48 ± 1.26

101.44 ± 0.96

100 ± 1.95

100.72 ± 1.65

100.3 ± 1.65

100.21 ± 0.94

Eradex Forte® Suspension

 R% ± S.D

*4

*2.5

99.09 ± 1.21

99.78 ± 1.32

100.25 ± 1.96

99.39 ± 1.74

100.004 ± 1.53

100.62 ± 1.94

99.24 ± 1.83

99.45 ± 1.77

101.98 ± 0.39

  1. *Dosage form ratio