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Table 4 Determination of atorvastatin calcium and vitamin D3 by the proposed method in comparison with the reported method [30]

From: Development and validation of an eco-friendly HPLC–UV method for determination of atorvastatin and vitamin D3 in pure form and pharmaceutical formulation

Parameter

Proposed method

Reported method [30]

Atorvastatin calcium

Vitamin D3

Atorvastatin calcium

Vitamin D3

Mean recovery$ % ± SD

102.87 ± 0.97

101.35 ± 2.24

100.5 ± 0.04

101.7 ± 0.15

RSD (%)

0.95

2.21

0.04

0.15

Student-t-test*

0.072

0.878

F-test*

0.003

0.009

N

5

3

  1. $Mean of five determinations for proposed method and three determinations for reported method
  2. *Tabulated values of t and F values at p = 0.05 are 2.776 and 19.2
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BMC Chemistry

ISSN: 2661-801X

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