BMC Chemistry

Table 1 Optimization of the formation of 4a^a

From: Synthesis of N,O-bidentate organic difluoroboron complexes and their photophysical studies


Entry	Base	Temp (^oC)	Solvent	Yields^b
1	^tBuOK	rt	THF	73%
2	K₂CO₃	rt	THF	None
3	KOH	rt	THF	None
4	Et₃N	rt	THF	None
5	^tBuOK	60	THF	31%
6	^tBuOK	80	THF	10%
7	^tBuOK	100	THF	trace
8	^tBuOK	rt	DCM	10%
9	^tBuOK	rt	1,4-Dioxane	trace
10	^tBuOK	rt	DMF	None

^aReaction conditions: 1a (0.20 mmol), 2 (0.30 mmol), base, solvent, BF₃∙THF (0.60 mmol), N₂. ^bYields were determined by ¹H NMR analysis of the crude product using 1,3,5-trimethoxybenzene as the internal standard. Temp, Temperature

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ISSN: 2661-801X

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