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Scheme 1 | BMC Chemistry

Scheme 1

From: Synthesis, α-Glucosidase inhibitory activity and docking studies of Novel Ethyl 1,2,3-triazol-4-ylmethylthio-5,6-diphenylpyridazine-4-carboxylate derivatives

Scheme 1

Synthesis of target compounds. Synthesis of target compounds. Reagents and conditions: (a) hydrazine hydrate, methanol, reflux, 15 min.; (b) Na, EtOH, diethyl malonate, reflux; (c) Lawesson’s reagent, toluene, reflux, 18 h; (d) propargyl bromide, DMF, K2CO3, 50 °C; (e) Et3N, DCE, r.t.; (f) NaN3, DMSO, r.t.; (g) Et3N, DMF, CuI, r.t

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BMC Chemistry

ISSN: 2661-801X

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