Fig. 5
From: In-silico engineering of RNA nanoplatforms to promote the diabetic wound healing
Energy analysis in bioresponsive polymeric nanocarriers and RNAis interaction. (A) van der Waals interaction energy of PLGA, PEI, and Chitosan with miRNA antisenses and siRNAs, (B) Electrostatic interaction energy of PLGA, PEI, and Chitosan with miRNA antisenses and siRNAs, (C) Total interaction energy of PLGA, PEI, and Chitosan with miRNA antisenses and siRNAs, (D) Different between initial and final Gyration radius of loaded miRNA antisenses and siRNAs, (E) Average SASA of loaded miRNA antisenses and siRNAs, (F) RMSD of loaded miRNA antisenses (1) during the MD simulation