Fig. 4
From: In-silico engineering of RNA nanoplatforms to promote the diabetic wound healing
The snapshots of MD simulations among (A-C) miRNA antisense 1/PLGA carrier, and (D-F) miRNA antisense 3/PLGA carrier in the (A and D) input, (B and E) middle, and (C and F) output modes of the simulation. Figures (G-I) show the output interaction modes of (G) miRNA antisense 1, (H) miRNA antisense 2, (I) miRNA antisense 3, (J) SiRNA 1, (K) SiRNA 2, (L) SiRNA 3, with PLGA carrier. In this figures, dark green, red, and light green molecules represent PLGA polymer, Oxygen atoms, and Carbon atoms, while white, blue, and light brown represent Hydrogen, Nitrogen, and Phosphorus atoms, respectively. Figures (M-R) show the output interaction modes of (M) miRNA antisense 1, (N) miRNA antisense 2, (O) miRNA antisense 3, (P) SiRNA 1, (Q) SiRNA 2, (R) SiRNA 3, with PEI carrier, while Figures (S-X) show the output interaction modes of (S) miRNA antisense 1, (T) miRNA antisense 2, (U) miRNA antisense 3, (V) SiRNA 1, (W) SiRNA 2, (X) SiRNA 3, with Chitosan carrier. In this Figures, silver, yellow, red, and light green molecules represent PEI polymer, Chitosan polymer, Oxygen, and Carbon atoms, while white, blue, and light brown represent Hydrogen, Nitrogen, and Phosphorus atoms, respectively