Table 5 Greenness evaluation and comparison of the developed methods and reported one
| Â | Developed spectrophotometric methods | Reported UPLC method [26] | ||
|---|---|---|---|---|
NEMI |
|
| ||
Analytical Eco-scale | Parameters | PPs | Parameters | PPs |
Reagents | Reagents | |||
Ethanol | 4 | Methanol | 6 | |
Acetonitrile | 4 | |||
Water | 0 | |||
Orthophosphoric acid | 1 | |||
Instrument spectrophotometer | Instrument UPLC | |||
Energy: <0.1kWh per sample | 0 | Energy: <0.1kWh per sample | 0 | |
Occupational hazards | 0 | Occupational hazards | 3 | |
Waste < 10 mL | 3 | Waste (1–10 mL) | 3 | |
Total PPs | 7 | Total PPs | 17 | |
Analytical Eco-scale score | 93 | Analytical Eco-scale score | 83 | |
AGREE tool |
| Â | ||
