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Table 4 Greenness assessment by AGREE tool and methods comparison

From: Classical versus chemometrics tools for spectrophotometric determination of fluocinolone acetonide, ciprofloxacin HCl and ciprofloxacin impurity-A in their ternary mixture

Method

Linearity rangea (μg/mL)

Analyzed samples

Solvent used

AGREE assessment

CIP

FLU

Reference [28]

1–15

CIP and FLU

Methanol

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Reference [30]

3–15

This work

1–40

0.6–20

CIP, FLU and CIP imp-A

Phosphate buffer, pH 3.6

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  1. aThe widest range was chosen for each work