BMC Chemistry

Table 3 Application of the proposed method for the determination of OMG, MET, and EZT in pure forms

From: Analytical quality-by-design approach for development and validation of HPLC method for the simultaneous estimation of omarigliptin, metformin, and ezetimibe: application to human plasma and dosage forms

Parameter	OMG		MET		EZT
Parameter	Conc. taken (µg/mL)	%Found^a	Conc. taken (µg/mL)	%Found^a	Conc. taken (µg/mL)	%Found^a
	0.2	97.5	0.5	97.2	0.1	100.7
	0.25	100.44	1.0	99.54	0.2	104.15
	0.3	96.8	2.5	98.2	0.3	100.2
	0.5	102.82	5.0	101.21	0.4	99.2
	0.75	100.97	10.0	99.83	0.5	100.52
	1.0	98.83	15.0	100.97	1.0	97.67
	1.5	100.79	20.0	99.06	1.5	100.93
	2.0	99.65	25.0	100.25	2.0	100.01
Mean		99.73		99.53		100.42
± SD		1.97		1.36		1.83
%RSD		1.972		1.365		1.825
% Error		0.695		0.48		0.648

^a Mean of three determinations.

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