BMC Chemistry

Table 4 Assay results for the determination of the studied drugs in pure form by the proposed and comparison methods

From: Green quality by design HPLC approach for the simultaneous determination of Bilastine and Montelukast

Compound	Proposed method			Comparison methods [17]
Compound	Amount taken (µg/mL)	Amount found (µg/mL)	% Found	% Found
BIL	1.0	1.00	100.29	101.30
	3.0	2.97	99.09	98.70
	15.0	14.89	99.30	100.43
	20.0	20.01	100.06
	30.0	30.22	100.74
	50.0	49.89	99.79
Mean	99.88			100.14
± S.D	0.62			1.32
t-test	0.31 (2.31)*
F-test	4.53 (5.41)*
MNT (PDA detector)	3.0	2.96	2.96	99.06
	7.0	6.86	6.89	100.94
	15.0	14.96	14.96	99.69
	30.0	30.09	30.09
	40.0	40.65	40.62
	50.0	49.44	49.48
Mean	99.59			99.90
± S.D	1.21			0.96
t-test	0.38 (2.31)*
F-test	1.49 (5.41)*
MNT (Fluorescence detector)	0.2	0.20	101.65	99.06
	0.7	0.68	98.04	100.94
	1.0	1.00	100.89	99.69
	3.0	3.00	100.13
	5.0	4.99	99.95
Mean	100.13			99.90
± S.D	1.35			0.96
t-test	0.34 (2.31)*
F-test	1.98 (9.01)*

Each result is the average of three separate determinations
^*The figures between parentheses are the tabulated t and F values at P = 0.05 [29]

Back to article page

ISSN: 2661-801X

Contact us

Submission enquiries: bmcchemistry@biomedcentral.com
General enquiries: ORSupport@springernature.com