Table 5 ADMET prediction for eight extracted compounds from CHEMBL
From: QSAR and molecular docking studies of isatin and indole derivatives as SARS 3CLpro inhibitors
Compound | Human intestinal absorption | ClogP | Ames test | Acute oral toxicity | Drug likeness | Drug score |
|---|---|---|---|---|---|---|
CHEMBL4524939 |  + (0.9816) | 5.36 | No | III | − 2.47 | 0.16 |
CHEMBL4458417 |  + (0.9816) | 4.02 | No | III | 6.12 | 0.56 |
CHEMBL4452760 |  + (0.9792) | 3.85 | No | III | 1.76 | 0.46 |
CHEMBL4565907 |  + (0.9774) | 4.00 | No | III | 2.59 | 0.51 |
CHEMBL4443007 |  + (0.9816) | 4.05 | Yes | III | 6.75 | 0.48 |
CHEMBL383761 |  + (0.9670) | 2.67 | No | III | − 3.73 | 0.34 |
CHEMBL210543 |  + (0.9914) | 3.10 | No | III | − 4.66 | 0.32 |
CHEMBL3103276 |  + (0.9761) | 3.43 | No | III | − 5.60 | 0.17 |