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Table 5 Determination of MOL by the proposed Ag–NPs method in Molnupiravir® capsules and application of standard addition technique

From: Earth-friendly-assessed silver-nanoparticles spectrophotometric method for rapid and sensitive analysis of Molnupiravir, an FDA-approved candidate for COVID-19: application on pharmaceutical formulation and dissolution test

Product

Recovery%b ± RSD

Standard addition

Taken (ng/mL)

Added (ng/mL)

Found (ng/mL)

Recovery (%)c

Molnupiravir® capsulesa

100.46 ± 0.76

500

100

99.13

99.13

300

304.23

101.41

500

506.95

101.39

700

698.13

99.73

900

893.99

99.33

Mean ± RSD

100.20 ± 1.12

  1. aMolnupiravir® capsules, labeled to contain 200 mg of MOL per capsule, batch number (HH2112584)
  2. bMean of five determinations
  3. cMean of three determinations
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BMC Chemistry

ISSN: 2661-801X

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