Table 2 Results of eco-scale analysis for the determination of MOL employing the proposed Ag–NPs method and the reported LC method

Parameters

 Reagents

  Methanol

–

12

  Acetonitrile

–

4

  Ammonium acetate

–

4

  AgNO₃

0

–

  PVP

0

–

  NaOH

2

–

  Phosphate buffer

0

–

 Instruments

  Spectrophotometer/LC–MS/MS

  Energy

0

[≤ 0.1 kWh/sample]

2

[> 0.1 kWh/sample]

  Occupational hazard

0

0

  Waste

3

6

  Total penalty points

Σ 5

Σ 28

  Analytical eco-scale total score^a,b

95

72

Excellent green analysis

Acceptable green analysis