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Table 6 Assay results for the determination of the ASP, ATR and RAM in prepared tablet

From: Micellar eco-friendly HPLC method for simultaneous analysis of ternary combination of aspirin, atorvastatin and ramipril: application to content uniformity testing

Compound

Proposed method

Comparison method [9]

Amount taken, (µg/mL)

% Found, %

% Found, %

ASP

62.5

98.95

100.52

125

101.02

99.45

187.5

99.77

100.18

Mean ± SD

 

99.91 ± 1.31

100.05 ± 0.547

t-test

0.20 (2.78)

 

F- test

3.64 (19.00)

ATR

25

99.16

98.54

50

99.91

101.18

75

99.67

99.63

Mean ± SD

 

99.58 ± 0.383

99.78 ± 1.33

t-test

 

0.26 (2.68)

 

F-test

 

11.99 (19.00)

RAM

6.25

99.44

100.67

12.5

101.22

99.42

18.75

100.11

100.18

Mean ± SD

 

100.26 ± 0.90

100.09 ± 0.63

t-test

 

0.26 (2.78)

 

F-test

 

2.04 (19.00)