Table 2 show the comparison between inhibition rate (IR %) of Cs/DOX-Cit-MNPs with different concentrations (6.5, 12.5, 25, 50 μg/ml) after 24, 48 and 72 h toward MCF-7 & WISH
Sample | Cells | IR, % | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | After 24Â h | After 48Â h | After 72Â h | |||||||||
| Â | Â | Drug concentration (mg) | |||||||||||
| Â | Â | 6.5 | 12.5 | 25 | 50 | 6.5 | 12.5 | 25 | 50 | 6.5 | 12.5 | 25 | 50 |
Cs/DOX-Cit-MNPs | Tumor cells (MCF-7) | 15 | 24 | 33 | 40 | 25 | 38 | 45 | 60 | 31 | 45 | 60 | 76 |
Normal cell (WISH) | 3 | 6 | 10 | 12 | 5 | 5 | 12 | 17 | 5 | 8 | 13 | 22 | |
Free DOX | Tumor cells (MCF-7) | 20 | 31 | 50 | 75 | 24 | 46 | 72 | 88 | 25 | 46 | 75 | 91 |
Normal cell (WISH) | 12 | 25 | 36 | 59 | 18 | 36 | 55 | 72 | 18 | 38 | 60 | 76 | |