Table 7 Comparison of the proposed HPLC method to the reported HPLC methods
Reported methods | Analytes separated | Linearity (µg/mL) of the drugs | Retention time | |
|---|---|---|---|---|
Impurities | Drugs | |||
Ref (49) | – | PCM | 5–30 | 3.07 |
ETO | 5–30 | 5.72 | ||
Ref (50) | – | PCM | 50–150 | 3.27 |
ETO | 6–18 | 6.12 | ||
Ref (51) | – | PCM | 8.3–41.5 | 3.12 |
ETO | 1–5 | 6.82 | ||
Ref (52) | – | PCM | 48–146 | 8.34 |
ETO | 6 -19 | 18.45 | ||
Ref (53) | – | PCM | 1200–3600 | 2.460 |
ETO | 1000 -3000 | 1.189 | ||
Proposed method | PAP, PHA | PCM | 1.5–30 μg /mL | 3.41 |
ETO | 1.5–30 μg /mL | 7.27 | ||