Development and validation of a novel Spectrofluorimetric method of oral anticoagulant Edoxaban via derivatization with 9-fluorenyl methyl chloroformate: green assessment of the method by Eco-Scale and ComplexGAPI

Table 5 Comparison between the suggested method and the recently reported methods

Method	Linear range	LOD	References
Spectrophotometric	5–25 µg/mL	0.654 μg/mL	[2]
HPLC–UV	2–10 µg/mL	0.225 μg/mL	[5]
Potentiometric	3.288–548.056 µg/mL	1.858 μg/mL	[15]
Our suggested method	5–25 ng/mL	1.49 ng/mL

ISSN: 2661-801X