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Table 1 Cytotoxicity of synthesized compounds against A-549, MDA-MB-231, and MRC-5 cell lines

From: Synthesis, biological evaluation and molecular docking of new triphenylamine-linked pyridine, thiazole and pyrazole analogues as anticancer agents

Cpd. No

IC50 (μM)

CC50 (μM)

 

A-549 cell line

MDA-MB-231 cell line

MRC-5 cell line

4a

0.04685

0.055

0.1372

4b

0.00803

0.0103

0.0971

4c

0.1536

0.193

0.864

4d

0.2328

0.318

1.0956

4e

0.0095

0.0147

0.0823

6a

0.141

0.172

0.9852

6b

0.0792

0.123

0.768

6c

0.0485

0.051

0.1432

6d

0.0954

0.139

0.6829

8

0.219

0.136

1.1046

9

0.127

0.268

1.295

10

0.128

0.111

0.973

Cisplatin

0.0244

0.012

0.0876

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BMC Chemistry

ISSN: 2661-801X

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