Scheme 2From: Design and synthesis of novel ureido and thioureido conjugated hydrazone derivatives with potent anticancer activitySynthesis of compounds 4a–4i. Reagents and conditions: i NH2NH2.H2O, Absolute EtOH, r.t., 96 h ii Ar-CHO, HCl, EtOH, r.t., 30 min; iii Ar′–N=C=X or Ar′–SO2–N=C=O, Acetone/DMF, reflux, 1 hBack to article page