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Table 5 Comparison and statistical assessment of the results obtained by the proposed and the reported methods

From: Application of green first derivative synchronous spectrofluorometric method for quantitative analysis of fexofenadine hydrochloride and pseudoephedrine hydrochloride in pharmaceutical preparation and spiked human plasma

Parameters Proposed method Reported method [9]
FEX PSE FEX PSE
Linearity range 100─1500 (ng/mL) 50─1000 (ng/mL) 10–80 (µg/mL) 5–40 (µg/mL)
LOD 24.15 (ng/mL) 12.88 (ng/mL) 0.75 (µg/mL) 0.27 (µg/mL)
% Ra 99.49 98.67 99.02 99.63
RSD 0.931 0.634 1.072 1.257
Student’s t-test (2.306)b 0.759 1.540
F-test (6.388)b 1.312 4.006
  1. a Average of five determinations
  2. b The values in parenthesis are tabulated values of “t “and “F” at (P = 0.05)