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Table 5 Comparison and statistical assessment of the results obtained by the proposed and the reported methods

From: Application of green first derivative synchronous spectrofluorometric method for quantitative analysis of fexofenadine hydrochloride and pseudoephedrine hydrochloride in pharmaceutical preparation and spiked human plasma

Parameters

Proposed method

Reported method [9]

FEX

PSE

FEX

PSE

Linearity range

100─1500 (ng/mL)

50─1000 (ng/mL)

10–80 (µg/mL)

5–40 (µg/mL)

LOD

24.15 (ng/mL)

12.88 (ng/mL)

0.75 (µg/mL)

0.27 (µg/mL)

% Ra

99.49

98.67

99.02

99.63

RSD

0.931

0.634

1.072

1.257

Student’s t-test (2.306)b

0.759

1.540

F-test (6.388)b

1.312

4.006

  1. a Average of five determinations
  2. b The values in parenthesis are tabulated values of “t “and “F” at (P = 0.05)