Table 5 Best fit alignment score obtained using PharmaGist
From: In-silico and in-vitro studies on the efficacy of mangiferin against colorectal cancer
Score | Features | Spatial features | Aromatic | Hydrophobic | Donors | Acceptors | Negative | Positive | Molecules |
|---|---|---|---|---|---|---|---|---|---|
The best fit alignment score of COX 2 inhibitor drugs | |||||||||
11.906 | 3 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | Bextra, celebrex, nimesulide, indomethacin, vioxx |
Best fit alignment score of COX 2 inhibitor drugs + Mangiferin | |||||||||
12.728 | 3 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | Bextra, celebrex, nimesulide, indomethacin, vioxx, mangiferin |