From: Design, synthesis, and bioactivity of ferulic acid derivatives containing an β-amino alcohol
Compd | Xoo | Xac | ||||
---|---|---|---|---|---|---|
Regression equation | R2 | EC50 (μg/mL) | Regression equation | R2 | EC50 (μg/mL) | |
D1 | y = 0.54x + 3.8 | 0.94 | 122.9 ± 4.9 | |||
D2 | y = 0.78x + 3.5 | 0.97 | 74.2 ± 3.9 | |||
D3 | y = 0.84x + 3.9 | 0.99 | 20.3 ± 0.9 | y = 0.92x + 3.5 | 0.96 | 37.3 ± 1.4 |
D5 | y = 0.87x + 3.7 | 0.93 | 27.1 ± 2.5 | |||
D7 | y = 1.16x + 3.0 | 0.98 | 45.4 ± 1.3 | y = 1.13x + 3.3 | 0.99 | 29.4 ± 4.1 |
D11 | y = 0.99x + 3.3 | 0.93 | 45.6 ± 0.5 | |||
D15 | y = 0.99x + 3.3 | 0.96 | 66.1 ± 4.7 | |||
D22 | y = 1.33x + 3.3 | 0.95 | 16.2 ± 1.5 | |||
D23 | y = 1.02x + 3.6 | 0.94 | 19.5 ± 0.6 | |||
D24 | y = 1.46x + 3.2 | 0.95 | 14.5 ± 0.8 | |||
BTa | y = 1.62x + 3.0 | 0.98 | 16.2 ± 3.4 | y = 0.83x + 3.6 | 0.95 | 46.8 ± 5.0 |
TCa | y = 0.93x + 3.4 | 0.97 | 44.5 ± 3.4 | y = 1.04x + 3.5 | 0.95 | 23.8 ± 4.9 |