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Table 5 Comparison between the proposed method and other reported methods for repaglinide determination in different matrices

From: Response surface optimization of a vortex-assisted dispersive liquid–liquid microextraction method for highly sensitive determination of repaglinide in environmental water by HPLC/UV

Sample Sample preparation Method LOD (ng/mL) LOQ (ng/mL) Refs.
Human plasma LLE HPLC–UV 10 20 [2]
Human plasma LLE ESI-LC–MS 1 1 [47]
Human plasma SPE HPLC–UV NR 20 [8]
Monkey plasma Protein precipitation LC–MS/MS NR 1 [6]
Rabbit plasma Protein precipitation HPLC–UV 18 55 [48]
Human urine - UPLC-MS/MS 0.10 0.40 [7]
Human urine Salting out HILIC-MS/MS NR 2 [10]
Urine SPE LC–MS/MS 5 NR [11]
Tablet Filtration and dilution Ion pair HPLC–UV 27 81 [49]
Tablet Filtration and dilution HPLC–UV NR 100 [50]
Tablet Filtration and dilution HPLC–UV 100 310 [51]
Tablet Filtration and dilution HPLC–UV 278 840 [52]
Tap water vortex assisted-DLLME HPLC–UV 0.40 1 This work
  1. LLE: liquid–liquid extraction; SPE: solid-phase extraction; ESI: electrospray ionization; NR: not reported