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Table 5 Comparison between the proposed method and other reported methods for repaglinide determination in different matrices

From: Response surface optimization of a vortex-assisted dispersive liquid–liquid microextraction method for highly sensitive determination of repaglinide in environmental water by HPLC/UV

Sample

Sample preparation

Method

LOD (ng/mL)

LOQ (ng/mL)

Refs.

Human plasma

LLE

HPLC–UV

10

20

[2]

Human plasma

LLE

ESI-LC–MS

1

1

[47]

Human plasma

SPE

HPLC–UV

NR

20

[8]

Monkey plasma

Protein precipitation

LC–MS/MS

NR

1

[6]

Rabbit plasma

Protein precipitation

HPLC–UV

18

55

[48]

Human urine

-

UPLC-MS/MS

0.10

0.40

[7]

Human urine

Salting out

HILIC-MS/MS

NR

2

[10]

Urine

SPE

LC–MS/MS

5

NR

[11]

Tablet

Filtration and dilution

Ion pair HPLC–UV

27

81

[49]

Tablet

Filtration and dilution

HPLC–UV

NR

100

[50]

Tablet

Filtration and dilution

HPLC–UV

100

310

[51]

Tablet

Filtration and dilution

HPLC–UV

278

840

[52]

Tap water

vortex assisted-DLLME

HPLC–UV

0.40

1

This work

  1. LLE: liquid–liquid extraction; SPE: solid-phase extraction; ESI: electrospray ionization; NR: not reported