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Table 2 Evaluation of cytotoxicity of some chosen synthesized compounds against hepatocellular carcinoma cells lines (HepG-2)

From: Synthesis, screening as potential antitumor of new poly heterocyclic compounds based on pyrimidine-2-thiones

Sample conc. (µg ml−1)

Cell viability (%)

4a

6a

7a

9a

10a

13a

14a

Vinblastine standard

50.000

23.34

30.79

34.92

37.26

19.85

39.61

28.60

15.12

25.000

32.67

40.42

43.43

48.67

24.57

52.16

39.09

17.33

12.500

41.82

52.87

56.33

61.15

35.87

66.03

44.88

24.18

6.250

60.09

69.32

61.38

68.71

52.49

73.52

62.94

46.87

3.125

72.57

84.17

86.89

88.34

61.22

89.56

76.14

55.18

1.560

86.53

94.37

97.09

98.03

78.86

99.12

88.25

73.98

0.000 (DMSO)

100.00

100.00

100.00

100.00

100.00

100.00

100.00

100.00