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Table 2 Evaluation of cytotoxicity of some chosen synthesized compounds against hepatocellular carcinoma cells lines (HepG-2)

From: Synthesis, screening as potential antitumor of new poly heterocyclic compounds based on pyrimidine-2-thiones

Sample conc. (µg ml−1) Cell viability (%)
4a 6a 7a 9a 10a 13a 14a Vinblastine standard
50.000 23.34 30.79 34.92 37.26 19.85 39.61 28.60 15.12
25.000 32.67 40.42 43.43 48.67 24.57 52.16 39.09 17.33
12.500 41.82 52.87 56.33 61.15 35.87 66.03 44.88 24.18
6.250 60.09 69.32 61.38 68.71 52.49 73.52 62.94 46.87
3.125 72.57 84.17 86.89 88.34 61.22 89.56 76.14 55.18
1.560 86.53 94.37 97.09 98.03 78.86 99.12 88.25 73.98
0.000 (DMSO) 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00