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Table 6 Data of the analysis of nicotinamide and tretinoin in the synthetic pharmaceutical preparation with the Proposed Method

From: Development and validation of derivative UV spectroscopic method for simultaneous estimation of nicotinamide and tretinoin in their binary mixtures and pharmaceutical preparations

Ingredient/labeled concentration (w/w%)

Nicotinamide (4%)

Tretinoin (0.1%)

 Wavelength (nm)/deriv. order

 253/D1

 245/D2

 269/D2

 348/D0

Recovery ± RSD %a

101.00 ± 0.90

100.40 ± 1.22

99.30 ± 0.88

93.70 ± 1.39

Recovery ± RSD %b

101.70 ± 1.42

–

101.16 ± 1.62

98.37 ± 0.90

  1. aIn solution preparation
  2. bIn cream preparation
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BMC Chemistry

ISSN: 2661-801X

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