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Table 5 Stability studies of compound 1 in aloe vera juice and White Lotion USP for pH

From: Aesculin based glucosamine-6-phosphate synthase inhibitors as novel preservatives for food and pharmaceutical products: in-silico studies, antioxidant, antimicrobial and preservative efficacy evaluation

Compound(s)

Change in pH with time

0 month

1 month

2 month

3 month

4 month

5 month

6 month

Compound 1

#

5.8 ± 0.45a

6.0 ± 0.50b

5.9 ± 0.04c

5.7 ± 0.21d

5.8 ± 0.34e

5.9 ± 0.02f

5.8 ± 0.44 g

@

5.6 ± 0.23a

5.9 ± 0.44b

5.7 ± 0.44c

5.8 ± 0.23d

5.7 ± 0.39e

5.8 ± 0.29f

6.0 ± 0.43 g

Sodium benzoate

#

5.6 ± 0.23

6.9 ± 0.44

5.7 ± 0.44

5.8 ± 0.23

6.7 ± 0.39

6.8 ± 0.29

7.0 ± 0.43

@

5.7 ± 0.55

5.6 ± 0.89

5.6 ± 0.34

5.6 ± 0.46

6.0 ± 0.59

6.0 ± 0.93

5.6 ± 0.18

Propyl paraben

#

5.8 ± 0.07

5.7 ± 0.67

5.6 ± 0.67

5.7 ± 0.79

5.8 ± 0.35

5.9 ± 0.59

5.8 ± 0.28

@

5.9 ± 0.56

5.6 ± 0.98

6.0 ± 0.89

5.8 ± 0.19

5.6 ± 0.18

5.5 ± 0.78

5.7 ± 0.82

Ethyl paraben

#

5.6 ± 0.23

6.9 ± 0.44

5.7 ± 0.44

5.8 ± 0.23

6.7 ± 0.39

6.8 ± 0.29

7.0 ± 0.43

@

5.7 ± 0.55

5.6 ± 0.89

5.6 ± 0.34

5.6 ± 0.46

6.0 ± 0.59

6.0 ± 0.93

5.6 ± 0.18

  1. # Aloe vera juice; @ White lotion USP
  2. All pH values were recorded in triplicate (n = 3) and the mean values are presented. Different letters mean p < 0.05 in each line by One-way ANOVA test
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BMC Chemistry

ISSN: 2661-801X

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