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Table 3 Result of antimicrobial activity of aesculin derivatives (pMIC values)

From: Aesculin based glucosamine-6-phosphate synthase inhibitors as novel preservatives for food and pharmaceutical products: in-silico studies, antioxidant, antimicrobial and preservative efficacy evaluation

Compound(s) pMIC values in µM/mL
P. mirabilis P. aeruginosa S. aureus E. coli C. albicans A. niger
Compound 1 1.53 1.23 1.23 2.13 1.83 1.53
Compound 2 1.26 1.26 1.26 1.57 1.57 0.96
Aesculin  < 0.83  < 0.83  < 0.83  < 0.83  < 0.83  < 0.83
Streptomycin 1.06 1.36 1.06 1.96
Ciprofloxacin 1.12 1.42 1.12 1.42
Ampicillin 1.14 0.84 0.84 1.74
Fluconazole 1.08 1.38