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Table 3 Result of antimicrobial activity of aesculin derivatives (pMIC values)

From: Aesculin based glucosamine-6-phosphate synthase inhibitors as novel preservatives for food and pharmaceutical products: in-silico studies, antioxidant, antimicrobial and preservative efficacy evaluation

Compound(s)

pMIC values in µM/mL

P. mirabilis

P. aeruginosa

S. aureus

E. coli

C. albicans

A. niger

Compound 1

1.53

1.23

1.23

2.13

1.83

1.53

Compound 2

1.26

1.26

1.26

1.57

1.57

0.96

Aesculin

 < 0.83

 < 0.83

 < 0.83

 < 0.83

 < 0.83

 < 0.83

Streptomycin

1.06

1.36

1.06

1.96

–

–

Ciprofloxacin

1.12

1.42

1.12

1.42

–

–

Ampicillin

1.14

0.84

0.84

1.74

–

–

Fluconazole

–

–

–

–

1.08

1.38

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BMC Chemistry

ISSN: 2661-801X

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