Antibacterial and antioxidant activities of extracts and isolated compounds from the roots extract of Cucumis prophetarum and in silico study on DNA gyrase and human peroxiredoxin 5

Table 6 In silico drug-likeness predictions of isolated compounds computed by SwissADME

Compounds	Formula	Mol. Wt. (g/mol)	NHD	NHA	NRB	TPSA (A^°2)	LogP iLogP)	Lipinski’s rule of Five Violation
1	C₄₆H₆₆O₆	715.01	1	6	10	105.58	5.19	Yes
2	C₂₂H₃₀O₄	358.47	1	4	0	71.44	2.4	0
3	C₁₄H₂₈O₂	228.37	1	2	12	37.3	3.32	0
4	C₂₉H₄₈O	412.69	1	1	6	20.23	5.1	Yes
5	C₂₉H₄₈O	412.69	1	1	5	20.23	4.79	0
5	Ciprofloxacin	401.45	2	9	5	136.13	0.963	0

NHD: Number of Hydrogen donor; NHA: Number of Hydrogen acceptor; NRB: Number of rotatable bonds; TPSA: total polar surface area

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