Table 9 Preliminary cytotoxicity screening of synthesized 1,3,4-oxadiazole derivatives [31]
From: Therapeutic potential of oxadiazole or furadiazole containing compounds
Compound | IC50 μM | |
|---|---|---|
HeLa | MCF-7 | |
12a | 79.7 | 81.6 |
12b | 30.4 | 23.5 |
12c | 45.6 | 28.6 |
13a |  ≥ 100 |  ≥ 100 |
13b |  ≥ 100 |  ≥ 100 |
13c | 80.1 | 78.3 |
13d | 58.8 | 62.4 |
13e |  ≥ 100 |  ≥ 100 |
13f | 100.3 |  ≥ 100 |
13 g |  ≥ 100 |  ≥ 100 |
13 h |  ≥ 100 |  ≥ 100 |
13i |  ≥ 100 |  ≥ 100 |
14a |  ≥ 100 |  ≥ 100 |
14b | 62.9 | 60.9 |
14c |  ≥ 100 |  ≥ 100 |
Standard | 3.5 | 3.5 |