Table 4 Antimicrobial activity of the titled compounds (5a-5f) [5]
From: Therapeutic potential of oxadiazole or furadiazole containing compounds
Compound | Diameter of zone of inhibition (mm) | ||||
|---|---|---|---|---|---|
Antibacterial activity | Antifungal activity | ||||
S. aureus | S. pyrogenes | E. coli | P. aeruginosa | C. albicans | |
5a | 10 | 13 | 12 | 08 | 14 |
5b | 13 | 11 | 14 | 09 | 12 |
5c | 12 | 13 | 15 | 09 | 14 |
5d | 12 | 11 | 13 | 10 | 13 |
5e | 09 | 09 | 10 | 07 | 11 |
5f | 08 | 09 | 09 | 06 | 10 |
Amikacin | 16 | 15 | 17 | 18 | – |
Ketoconazole | – | – | – | – | 18 |