Table 22 HIV inhibition activities (reverse transcriptase inhibitor) with therapeutic index [60]
From: Therapeutic potential of oxadiazole or furadiazole containing compounds
Compound | EC50 (μM) | IC50 (μM) | Therapeutic index |
|---|---|---|---|
45 | 3.24. 10–3 | 1.88 | 2.88. 10–7 |
47a | 1.1. 10–5 | 12.89 | 66.24. 10–8 |
47b | 5.26. 10–4 | 1.44 | 3.15. 10–7 |
48a | 5.23. 10–4 | 12.44 | 5.78. 10–6 |
48b | 1.56. 10–3 | 3.11 | 3.45. 10–6 |
49a | 3.81. 10–3 | 2.12 | 8.14. 10–6 |
52 | 2.72. 10–3 | 2.9 | 5.12. 10–6 |