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Table 6 Anticancer screening results of the synthesized compounds (T1–T20)

From: Synthesis and biological evaluation of heterocyclic 1,2,4-triazole scaffolds as promising pharmacological agents

Compounds

IC50 (μM)

Compounds

IC50 (μM)

T1

> 241.16

T12

> 206.80

T2

3.84

T13

> 202.61

T3

16.56

T14

128.25

T4

7.79

T15

> 217.55

T5

> 198.12

T16

169.25

T6

112.00

T17

> 217.55

T7

3.25

T18

> 208.02

T8

> 232.20

T19

> 226.91

T9

> 218.47

T20

> 247.15

T10

173.90

5-FU

25.36

T11

> 222.66

DMSO

1.50%

  1. Italics signifies the most active compound in comparison to the standard compound
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BMC Chemistry

ISSN: 2661-801X

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